894
HLAVNÍ42522701005185134178232252
TÉMA69222701003981147194
Specifika42533701003775111142157176194228264
diagnostiky7053370100375287125163202231259275309347
a1068337010034
léčby11183370100155082120156
multimorbidních129033701005996112139155215254278317332370408423453491
pacientů179733701003773103118153191218257
18019622701002869114
|350227010019
VNITŘNÍ4268043010746106127172220280301
LÉKAŘSTVÍ748804301074185130188236280325378400
/11948043010731
Vnitř1270804301074693112140166
Lék.1456804301074083122140
2023;69(3):173-1801615804301074487129173186232274298341362376414450493521559598643
/23038043010732
www.casopisvnitrnilekarstvi.cz442680430107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
of4255540833757
atrial49655408332547591123138
fibrillation64955408317347394110125140173194210248286
of9505540833756
the1021554083226095
European1131554083326990127167202234272
Society14185540833371104119153176209
of16425540833757
Cardiology1713554083407394132148186202240279311
(ESC)2039554083195185126146
Developed22005540834581113147163201241276316
with2530554083516789127
the2672554083226095
spe‑27825540832665100123
cial42565408331467894
contribution5376540833168107128150165204243265280318357
of9126540833857
the987654083226095
European1101654083326990127167202234272
Heart13926540834479111132156
Rhythm15676540833574104129167225
Association1810654083416996134167182214236251289327
(EHRA)2156654083185195131174193
of23686540833756
the2443654083215994
ESC,25566540833366107120
Eur2694654083336991
He‑28036540834479102
art425754083325378
J.5187540832437
20215707540833468101132
Feb7187540833266105
1;42(5):373-498.839754083344277109127160179190226258292314350384419432
3.4258530853651
Farmer494854083326283141176198
C,7108540833952
et7808540833456
al.854854083324860
Clinical932854083405570108123155188203
assessment1153854083325985120147174231266304326
and14978540833270109
management16248540835789127160199233291326365386
of20288540833756
multimorbidity:21028540835895111133148206244266306321360375398431445
summary25658540832663121179211232266
of28498540833757
NICE4259540834560101134
guidance.574954083387691130162200232266278
BMJ.8679540833691117129
201610119540833569100132
Sep11589540833267107
21;354:i4843.1280954083346674109142177189204239275311344357
4.42510530853550
Barnett4881054083356788126160182205
K,70510540833549
Mercer76610540835488109139172193
SW,9711054083329099
Norbury108210540834482103142179200233
M,132710540835467
et140610540833455
al.14741054083314658
Epidemiology15451054083327085123157214229266281319357389
of194610540833755
multimorbidity201410540835693108130144201239260299314352366388421
and244710540833269107
implications256610540831572110125140171203224239276314340
for4251154083185576
health51411540833771102117139177
care,7031154083316384118129
research,8441154083215481115146167198235247
and110411540833168107
medical122311540835791130145176209224
education:145911540833472109141173194209247285296
A1768115408340
cross‑sectional18211154083305188114140161187222254277292330367399414
study.22471154083264986125156166
Lancet,380,37-43.242511540833164101133166188201235269304316350382400436468480
5.42512530853650
Valderas4931254083366782121156177210237
JM,7471254083257993
Starfield8581254083325386107127144179194233
B,110912540833548
Sibbald11751254083324786125158174213
B1405125408336
et145812540833457
al.15321254083324760
Defining16101254083458198115153168206245
comorbidity:187312540833168126164186226241280295318351365
implications225512540831573112128143175208229245283321347
for26201254083185678
under‑271512540833775115149171190
standing4251354083264982120159174212251
health69213540833772104119142180
and88713540833270109
health101113540833873105120142181
services.12071354083266182117133165198225239
Ann146113540834179117
Fam159413540833261119
Med.172913540835489129142
2009;7(4):357-363.188613540833468105140152185202235252264299332366384416451485497
6.42514530853652
de49514540833873
Groot58714540834365102141163
V,76814540833645
Beckerman83114540833671103133168189247280318
H,116714540834457
Lankhorst124314540833165103133172210232259282
GJ,15441454083436981
et164414540833456
al.17191454083324760
How179714540834483134
to194914540832259
measure202714540835792124150188209243
comorbidity.228814540833268127165187226242281296318352362
a2669145408331
critical2719145408331526890106138171186
review4251554083215587103137189
of62915540833756
available7011554083326396111126159198214249
methods.96515540835792115153191231257271
J1251155408324
Clin12901554083405570108
Epidemiol.14141554083327187125160218233271287300
2003;56(3):221-229.173015540833468104137148184218237271288300335369401420451485519530
7.42516530853645
Huntley48816540834482120141157192223
AL,7291654083417386
Johnson83316540832462101139165203242
R,109216540833650
Purdy11591654083357294132164
S,134016540833345
et140316540833456
al.14771654083324760
Measures155416540835590122148186207241268
of183916540833757
multimorbidity191316540835895111133148206244266305321360375397431
and236216540833170109
morbidity248816540835796117157173211227249283
bur‑27881654083397798118
den42517540833873111
for5501754083185678
use6421754083376398
in75417540831553
primary8211754083396076133166187221
care10561754083316485119
and118917540833270109
community131217540833269127185222260275298331
settings:16581754083266183107123160199226238
a1910175408332
systematic19561754083265986109143201233255270302
review22721754083215587103137189
and247517540833169108
guide.25981754083387590129164176
Ann278817540834180118
Fam42518540833262120
Med.56018540835489129142
Mar‑Apr71718540835587109128170209231
2012;10(2):134-41.96318540833468100130142172204223257275287317347382405442472481
8.42519530853652
Newschaffer49819540834580132159192230263282301336358
CJ,8761954083406780
Bush97619540833674100139
TL,11351954083336680
Penberthy123619540833569107147183204229267298
LT.15551954083326170
Comorbidity164619540834077136175197237252291307330364
measurement203019540835893125152190211245304339378399
in245019540831553
elderly25241954083345089124145161193
fema‑273819540831953112144167
le42520540831550
breast4902054083396095126153176
cancer68220540833164102134168189
patients8862054083397294109144182203231
with11332054083506688126
administrative127520540833271129144182197223246267300322337370404
and169520540833270109
medical181920540835793132147179212227
records20622054083215587124146184210
data,22882054083387092125138
J2441205408324
Clin24812054083405570108
Epidemiol.26042054083337287126161219234272288301
1997,50:725-733.42521540833464100133138173207221254288323345376411443456
9.42522530853648
Charlson48622540834076107127141166203240
ME,7382254083558799
Charlson84922540834076107127142166203240
RE,11022254083356779
Peterson11932254083366889121141167203240
JC,14462254083246475
et153422540833455
al.16012254083324657
The167122540833270104
Charlson178722540834077108127142167203240
comorbidity204022540833167124161181219233271284305338
index23902254083155189122153
is255522540831539
adapted260722540833269100138159191229
to284922540832157
predict4252354083385890127141171193
costs6272354083316691112138
of77423540833755
chronic8382354083316786121158171201
disease10482354083385176108138163196
in125323540831551
primary13132354083385872127158177209
care15312354083316281113
patients.16542354083386989102135171191217228
J1892235408324
Clin19252354083405366102
Epidemiol.20372354083326982119152208221257271282
2008;61(12):1234-1240.232823540833466100134144178206219249277293303331359392425446475503533566577
10.4252453085367085
Salvi5252454083326581113129
F,66924540833339
Miller7232454083547085100135156
MD,894245408355101112
Grilli1021245408344658196111126
A,116224540834155
et123324540833456
al.13042454083324760
A1380245408340
manual143624540835789127165197213
of166424540833757
guidelines17362454083387591129164180195233268295
to204624540832258
score21202454083265895117151
the22862454083226095
modified239624540835796135150168185220259
cumula‑267124540833169127164179212234
tive4252554083223769104
illness543255408315304583118145171
rating729255408320537590128167
scale9112554083265891106141
and106725540833169108
its11902554083153765
validation1269255408332658095134166188203241280
in156325540831553
acute163025540833264102124158
hospitalized180225540833876103142157180213228243272306346
elderly21622554083345089124145161192
patients.J23692554083387193108143181203230244270
Am265425540834199
Geri‑276725540834479101116138
atr4252654083325475
Soc.51526540833371104117
200864726540833569105140
Oct;56(10):1926-31.80326540834779103116152186205237268286298328358391425448481512521
11.4252753085366678
Donnan52027540834584122160193231
PT,7672754083356978
Dorward86227540834584105159191213251
DW,1129275408346103113
Mutch125927540835492114145183
B,145927540833548
et152327540833457
al.15962754083324760
Development167327540834580113147163201240299334372393
and208327540833270109
validation2208275408332658095134166188203241280
of250427540833857
a2577275408332
model262627540835796135170186
for28282754083195678
predicting4252854083396094134149181205220258297
emergency73628540833492127148186221259291325
admissions107428540833271129144170197211249288314
over140228540833769103124
the15402854083216095
next164828540833873104128
year17902854083316597118
(PEONY):19212854083195587134180216238249
a2184285408332
UK222928540834479
historical23222854083375278102139160176208241256
cohort259128540833268107145167192
stu‑27962854083264987109
dy.4252954083387080
Archives5202954083416394132147179214240
of77629540833756
Internal8482954083145274108129167200215
Medicine.107929540835489129144176191229264276
2008;137029540833468105140152
168(13):1416-1422.153829540833465100119151181198210240271301332356387418450485497
12.4253053085366883
Hippisley‑Cox5213054083445998137153178194228260281324361391
J,92530540832435
Coupland97330540834077115154169201239278
C.126430540834053
Predicting13293054083355690129144176200215253291
risk1633305408321366292
of173830540833756
emergency180730540833491126147185220258290323
admission214330540833170128143169195210247286
to244130540832259
hospital251330540833775101140156178210226
using27523054083376377115154
primary4253154083396076134166187221
care6623154083316485120
data:7983154083387092125137
Derivation95131540834581102117150183205220258296
and126331540833270109
validation1388315408332658095134166188203241280
of168431540833757
QAdmissions175731540834786125183198224250265303342368
score.21413154083265995117151163
BMJ232031540833691117
Open.245331540834786122160173
2013264231540833569100130
Aug278931540834077117
19;3(8):e003482.4253254083346477112130164182194228264300333369405438451
13.4253353085366883
Von52633540833672110
Korff6543354083357294116135
M,80633540835568
Wagner89233540835788127165200222
EH,11313354083337790
Saunders123833540833366103141180215237264
K.151933540833550
A1587335408341
chronic16463354083316990127166181213
disease18763354083385379114146173208
score21013354083275996117151
from22703354083184078136
automated24243354083316991128187219241275314
phar‑275633540833877109130150
macy42534540835790122155
data.5963454083387092125138
J749345408324
Clin7893454083405570108
Epidemiol.9123454083337187126161219234272288301
1992;45(2):197-203.122834540833464100133145180213230264282294324354387405436470504516
14.4253553085366984
Bernabeu‑Wittel5253554083357092130163202237275298355371394418452468
M,100835540835468
Para10913554083356788121
O,122835540834758
Voicehovska13013554083367287119153191229261288318352
J,166835540832436
et171935540833457
al;17913554083324759
EFIM18653554083336580135
Multimorbidity201535540835492108130145203241263303318357372395428
Working245935540835793115146162200239
Group.271335540834466103141180193
Competences42536540834077135174210232266304336370397
of83536540833857
internal9063654083145274108129167200215
medicine113536540835792132147179194232267
specialists141636540832665100133148180196210237260287
for17173654083195678
the18093654083215994
management191736540835890128160199234292327365387
of231836540833756
patients23883654083397293109143181203231
with26323654083516689127
mul‑277336540835795110132
timorbidity.4253754083223795133155194210249264286320330
EFIM7743754083326579134
multimorbidity92737540835795110132148205244265305321359375397431
working137637540835189110141157195234
group16293754083385996135174
position182137540833978105119142157195234
paper.207337540833972111147168178
Eur22703754083336990
J2379375408324
Intern24223754083155374108129168
Med.260837540835590130143
2023276937540833569102136
Mar;109:97-106.42538540835487108122152183218231267299318349380416429
15.4253953085366882
Lyness5203954083315998133159186
JM,7193954083247891
Niculescu8233954083456092129144179205237275
A,111139540834155
Tu117839540833366
X,125739540833851
et132139540833456
al.13893954083324760
The146239540833271106
relationship15813954083215470102123138176214240278293332
of192639540833756
medical199539540835792131146178210225
comorbidity223339540833168126164185225240279294316349
and259539540833270108
depre‑271639540833873112133167189
ssion4254054083265368106144
in58440540831553
older,6524054083375392127148158
primary8264054083386075133165187221
care10624054083316485119
patients.Psychosomatics.11974054083387193108143181203230244281307339371409447474512570603624640672699713
2006;47(5):435-9.192540540833469105140153187219236269288300334367400422457468
16.3047553085366985
European3151554083336990128167203235273
guide3443554083387590129164
for3626554083185678
management37235540835789127160199233291326365386
of41285540833757
frailty420455408318407388103126159
at43825540833254
individual4455554083155291107139155194231264279
level4753554083155082116132
including4904554083145284100137176191229268
recommen‑5191554083215588125183241276314336
dations3047654083387092107145184210
and32746540833270109
roadmap.3400654083215891130188220260272
https://www.advantageja.eu/images/D6.2_EuropeanGuide_Ma‑36896540833859841231501621892102613143673784124514845175555766096486836987307447788168428589169489871022104910751122115711701206124312781315133613731413144814801518156316011616165516901726178318161838
nagement.pdf30477540833870109144202237275296310350389409
17.3047853085366878
Butchart3146854083367497128167200221246
A,34138540834156
Kerr3490854083357091114
EA,3624854083337791
Heisler3736854083458096122138173195
M,39518540835569
et40418540833457
al.4119854083324861
Experience42018540833366106142164180215253286320
and45428540833271110
management46738540835891130162202237296332370392
of50868540833857
chronic5164854083327092130169184217
pain5401854083397388127
among30479540833289127166205
patients3264954083397293108143181202230
with3507954083506588126
other3646954083375997131152
complex38119540833168126165181216247
chronic4071954083316990127165180212
conditions.42969540833167106144160182197235273299313
Clin4622954083395469107
J474295408324
Pain.4779954083356681119132
200949249540833468104139
May;25(4):293-8.50769540835486117130165200217250267279314348381402438451
18.30471053085366985
Boyd314910540833574105143
CM,330910540833995108
Darer34331054083457899133154
J,360310540832436
Boult365610540833573111127149
C,382110540834053
et389010540833456
al.39631054083314760
Clinical40391054083405570108123155188203
practice42581054083396093125150165197230
guidelines45051054083387590129164180195233268294
and481610540833169108
quality494110540833775107123138160194
of515110540833757
care52241054083316485119
for53591054083185678
ol‑54531054083375375
der30471154083387394
patients31571154083387193108143181203230
with34031154083506688126
multiple354511540835795110132148187203237
comorbid379811540833168126165186226241280
diseases.40931154083395480115147173208235249
JAMA.435711540832464120162176
2005;294:716-24.454911540833468104138149184218254266299332363386417449462
19.30471253085366982
Guthrie314812540834482104143164179214
B,338112540833548
Payne34481254083356798137172
K,363912540833549
Alderson37071254083415796131152179217256
P,398212540833539
et404112540833356
al.41161254083324760
Adapting419512540834179112151173188226265
clinical4479125408331476199114146179195
guidelines46931254083387591129164180195233268295
to500712540832158
take50841254083225585119
account52221254083326495132170208229
of547012540833857
multimorbidity.304713540835795110133148206244266305321360375397431441
BMJ.350313540833691116129
2012;345:e6341.364713540833468100130143178213246257291327361396426436
20.30471453085367287
Leśniak31471454083316592130145177207
W,336614540835867
Morbidoni344614540835593114154169208246284299
L,375814540833145
Dicker38161454083456092122156177
D,400614540834556
et407514540833456
al.41441454083324760
EFIM42171454083326579134
Clinical43641454083395469107122154187202
practice45791454083386093125149164196229
guidelines48211454083387691129164180195232267294
adaptation512814540833170102141163196218233271309
for54501454083185677
internists30471554083155374108129168183209232260
–3322155408335
an337215540833270
EFIM34571554083336680135
methodology.Eur360715540835893115153191231269285323363395405439476497
J4119155408324
Intern41591554083145274108129167
Med.434215540835489129142
2020;77:1-5.449915540833469101135148181216226256274308320
21.30471653085367082
Kostev31431654083357299122156188
K,334516540833549
Jacob34081654083245688125165
L.358616540833245
Multimorbidity364516540835492108130145203241263303318357372395428
and408716540833270109
polypharmacy42091654083397894125165204236257316348380414
among463616540833290128167206
elderly48551654083345089124145161193
people506116540833974113153169203
followed5278165408318567287125176211250
in304717540831553
general311517540833873111146167200216
practices33461754083386093125149165197230257
in361817540831553
Germany.368617540834479101159192230260270
Eur39711754083337091
J4077175408324
Intern41171754083145274108129167
Med.430017540835489129142
2018445717540833469100131
Sep;55:66-68.460417540833267106119154186197233268292329364378
22.30471853085367288
Masnoon315418540835487114151190228267
N,343918540834558
Shakib351618540833270102132149188
S,372218540833346
Kalisch‑Ellett3786185408335698499125158196218252267282317340364
L,416918540833145
et423218540833456
al.43071854083324760
What438618540835796128150
is455518540831440
polypharmacy?46141854083397793125165204236257316348380414437
A5070185408341
systematic51291854083265986109143201233255270302
re‑54501854083205578
view30471954083324782133
of319619540833756
definitions.32671954083397391108146161183199237275301315
BMC359719540833691131
Geriatr.374419540834379100116148169191201
2017396019540833569100130
Oct410519540834780104
10;17(1):230.42241954083346679109138155186201213248283317330
23.30472053085367287
Chang314720540834077110147186
TI,33462054083324961
Park34202054083356788118
H,355120540834457
Kim362120540833451108
DW,3742205408345102112
et386720540833456
al.39362054083314760
Polypharmacy,40082054083357288119159197229250309341373406416
hospitalization,443720540833775102140156178211226241270303325340378416429
and487820540833270109
mortality500020540835795116141173189203226259
risk:5272205408321366292106
a5391205408332
na‑54362054083376991
tionwide30472154083223775113164179218253
cohort331521540833269107145167192
study.35222154083264987126158168
Sci37062154083326479
Rep.380121540833570109122
2020393821540833468101135
Nov408921540834483115
3;10(1):18964.42192154083344676107127158173185214246280315352364
24.30472253085367186
Burt31492254083357394119
J,328422540832436
Elmore333622540833247105143165199
N,355122540834457
Campbell362422540834073130170209245260275
SM,391522540833387100
et403122540833456
al.41032254083324760
Developing417922540834580113147163201240256294333
a4527225408332
measure457522540835792124151188209243
of483422540833756
polypharmacy49062254083397793125165204236257315348380414
appro‑533522540833271111132170193
priateness30472354083396177109132166204240267294
in336223540831553
primary34362354083396177136169190225
care:36812354083326587121134
systematic38362354083276087111145204236258274307
review41632354083215689105140192
and437623540833270110
expert450723540833466106142164189
consensus471723540833169108135170209236273300
study.50382354083265088128160171
BMC523023540833591132
Med.538323540835591131144
2018304724540833468100131
Jun319324540832562100
13;16(1):91.33092454083346475105137156187202214249281290
25.30472553085367287
The314725540833271106
2019326625540833468100130
American340825540834199134155170202235273
Geriatrics369325540834479100116148169190206238265
Society397125540833270103118152175208
(AGS)419225540831859102135154
Beers435925540833570105126153
Criteria®4525255408340607698132153168200227
Update476525540834382121153175209
Expert498625540833365105140161185
Panel518425540833567105140155
(2019).53522554083185286118148165176
American304726540834198132153169200232270
Geriatrics33292654083447999115146168189204235263
Society360426540833270102117151173206
201938232654083346799128
Updated396426540834382121152174207246
AGS422326540834082115
Beers435126540833569104125152
Criteria®4515265408340607698131152167199225
for47532654083185576
Potentially48422654083347192125163184199231246260292
Inappropriate51462654083155284123162183220259280295327348381
Medication304727540835490129144176209231246284323
Use338527540834469104
in350527540831452
Older357227540834764102137159
Adults.374627540834179117132154182196
J3957275408324
Am399727540834199
Geriatr411127540834479100116148170191
Soc.431727540833371104117
2019444927540833569100131
Apr;67(4):674-694.459527540834180102115151184200233251263298331361384422455491504
26.30472853085367287
Naugler315528540834577115154169204225
CT,34012854083407584
Brymer35062854083355791149184206
C,373228540834053
Stolee38052854083335491107142177
P,400328540833539
et406328540833456
al.41402854083314760
Development422028540834681113148163201241299335373394
and463528540833170109
validation4764285408332658095134166188203241280
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an514128540833270
improving523228540831472111133170202218256295
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elderly35622954083345089123145161192
tool.37702954083215897113126
Can391129540834073111
J4037295408324
Clin40772954083405570108
Pharmacol.420029540833572105126184217249286302315
2000453029540833468104140
Summer;7(2):103-7.468629540833270127185220242255288304338356368398429462484516522
27.30473053085367180
Barry31443054083356889111145
PJ,33063054083365567
Gallagher33903054083447692107139178216251272
P,368030540833539
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C,389330540834053
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tool46183054083225998114
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doctors497030540833876108133170191218
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the52813054083226095
right53933054083213675113135
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screening39513154083265980114149187202240279
tool42443154083215897113
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elderly53353154083345089124145161193
patients.30473254083397293109143181203231244
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36(6):632-638.37953254083346887121139151186220252273310344378392
28.30473353085367288
O’Mahony315233540834760115148186224262293
D.346233540834556
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criteria3931335408331526890124145161193
for41413354083185677
potentially42353354083397799133171193208240255270302
inappropriate45543354083155285124163185222262283299331353387
medications/poten‑495733540835893132147179212234249287326352378415454476510548571
tial3047345408322376984
prescribing31493454083386094121153174190229244282321
omissions348834540833795110136163178216254280
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people:402134540833874113152168203216
origin42543454083375974113128166
and443734540833270109
progress.45633454083396198137159193219246260
Expert484034540833265105140161186
Rev504334540833671103
Clin51633454083405570108
Pharma‑528834540833573105126185217239
col.3047355408331688497
2020315935540833469101135
Jan;13(1):15-22.33103554083245694106136166184216230242272302324355390402
29.30473653085367285
Pazan31503654083356797130168
F,333536540833339
Weiss339136540835790106132158
C,356636540834053
Wehling363736540835790128144159197236
M.389036540835468
FORTA.397536540833380116150187202
The419436540833372107
FORTA431836540833380116150187
(Fit4522365408319526789
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The474936540833372107
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2021:517736540833468101133141
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2022324738540833468101136
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J.304740540832437
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