1494
PŘEHLEDOVÉ479422701004388130181216258306358404446
ČLÁNKY525622701003973122176223272
Poruchy356033701004079104142173210246
sekrécie38233370100286498123158189204239
rastového40793370100235887115153189224261300
hormónu439633701003675100161200237275
a4687337010034
ich47373370100154583
vplyv48363370100357489126164
na501633701003772
kostnú510433701003471101128167204
kvalitu532533701003371107122137164203
|5584227010018
E19564222701004170112
/35908043010732
Vnitř3667804301074592111139166
Lék.3852804301074184122140
2024;70(5):E16-E204012804301074487128168182224265290332355369412451490520563608651
/47088043010731
VNITŘNÍ48058043010746106127172220280301
LÉKAŘSTVÍ5127804301074185130188236280325378400
www.casopisvnitrnilekarstvi.cz42580430107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
PROHLÁŠENÍ4855510974387144199239292335376430452
AUTORŮ:95455109749101143200245299316
Prohlášení12865490984573119166187229263305352373
o167454909845
původnosti:17355490984693134179227274320354383404423
Publikace21745520954082127144161195233269308
byla2498552095447997133
zpracována26475520953378102139176218254291334371
s303455209529
využitím30795520953775119152169195212277
uvedené33725520954380119163203246286
literatury367455209517335997121158183226249288
a397855209536
nebyla40305520954383127163181217
publikována42635520954487132150166200243279316359396
ani4675552095367996
zaslána47875520953270100117153197233
k503655209534
recenznímu5086552095236299137180213257274340382
řízení485672095244174112156172
do6756720954387
jiného779672095173477117160203
média.100067209565105150167203218
Střet1235669098426998141170
zájmů:14216690983679100169215234
Žádný.16726720954380125168202213
Financování:19036690984161108149195232277318359406427446
Ne.23666720955191104
Registrace24876690984688135156190219248290326368
v287166909841
databázích:29296690984687116158205247284306342389408
Ne.33536720955191104
Projednání34756690984573119141183231278319365387
etickou3878669098417192128170214261
komisí:41556690984186155176210231250
Ano.44226720954790133147
LITERATÚRA426100001234978134189250318368438498567
1.42511600853648
Mirza4891161083547091122155
F,65911610833339
Canalis71311610834073111143158173200
E.92811610833246
Management98911610835487125157196231289324362384
of138811610833757
endocrine146011610833472111149182203219257292
disease:17671161083385379114146173208220
Secondary200311610833267100137175214247268302
osteoporosis:23201161083376487121160199238260297324338365377
pathophysiology2712116108339729413217042512620833977108135150188204242281313
and75612620833270109
management.88212620835890128160199234292327365387400
European13001262083336990127167203234272
journal15901262083155391112151183199
of180612620833857
endocrinology188112620833372111149181203218256295310349388420
/2319126208324
European23611262083336990128167203235273
Federation26511262083336710614116219521723242513620833776
of51613620833757
Endocrine58813620833370109148180201217255290
Societies.89313620833371104119154176191226253266
2015;173(3):R131-51.117513620833468100130140171200234252286303315351383413444463497528537
2.42514600853652
Hans49114620834476114141
D,64614620834556
Goertzen71614620834483118140164195229267
AL,9971462083417387
Krieg10981462083355773107147
MA,125914620835596111
et138414620833456
al.14541462083324760
Bone152814620833674113148
microarchitecture169014620835772104125163196217248286301323357390414452473507
assessed22111462083325985120147174209248
by247314620833970
TBS255714620833370102
predicts26731462083396094134149181205233
osteoporotic4251562083376487121160199238260297319334366
fractures8081562083194174106130168189223250
independent10761562083145291126165201239278313351373
of146615620833756
bone154015620833977116151
density:170815620833873111138153175209222
the19481562083215994
Manitoba206015620835487125140162199239272
study.23491562083265088127159169
J2535156208324
Bone257715620833573112147
Miner274115620835570108143164
Res.4251662083357097111
2011;26(11):2762-9.55116620833468100128136171205224255283297309344377409443463498509
3.42517600853651
Briot4891762083355772110132
K,63417620833550
Paternotte6971762083356789123144183221243267301
S,101117620833345
Kolta10701762083347288110143
S,122617620833346
et128517620833456
al.13541762083324760
Added142817620834179118153192
value16341762083316480117152
of179917620833857
trabecular18691762083224376115151184221237269290
bone217217620833978116151
score23371762083265895116150
to250117620832158
bone257317620833877116150
mineral2737176208357721101454251861083215469
density50718610833873111137152174208
for7281861083185677
prediction8181861083396094134149181205220258296
of112718610833756
osteoporotic11961861083386487121160199238259297318334366
fractures15741861083194174106130168189223250
in183718610831452
postmenopausal190218610833977104127185220258296336369406432465481
women:239618610835088146181219231
the26401861083226095
OPUS274818610834682126158
study.4251961083264987126158168
Bone.60919610833573112147159
2013;57(1):232-6.78319610833469100130142177210227258273285320354387407445458
4.42520600853652
Boutroy49820610833675114137159197229
S,74820610833246
Hans81520610834477116143
D,97920610834657
Sornay-Rendu10572061083337294133166198220258293332372410
E,148820610833347
et155620610833457
al.16342061083324861
Trabecular17162061083335184124161194232248281303
bone204020610833978117153
score22142061083265997119154
improves238920610831573113135173206241268
fracture26782061083194175108132171193227
risk425216108321366393
prediction5382161083396095134149181206221259298
in85621610831553
non-osteoporotic92921610833876115137177204227261300339378400437459475507
women:145621610835189147182221233
the17092161083226095
OFELY182521610834780113144175
study.20212161083264987126158168
Osteoporosis22102161083477497131170210249270308334349376
international260621610831553741081291682012222382764252261083387085
:531226108312
a563226108332
journal6162261083155391112151183199
established8352261083346184117157173188214252287326
as118222610833258
result12612261083205481119134156
of143822610833757
cooperation151522610833168107147182204237259274312351
between18862261083397497150184220258
the21652261083215995
European22802261083336990128167203235273
Foundation257422610833269108146185217239254292331
for4252361083185678
Osteoporosis5172361083477497131170209248270307334348375
and90623610833270109
the10292361083226095
National11392361083447798114152190223238
Osteoporosis13912361083477498131170210248270307334349375
Foundation178023610833370108146185218239255293331
of212623610833756
the21972361083215994
USA.230623610834475116131
2013;24(1):77-85.245223610833468100130141176208227259273285319353372408442454
5.42524600853650
McCloskey49424620835487128143181208238272304
EV,8162462083327079
Oden91324620834787122160
A,109124620834155
Harvey11652462083447697132166198
NC,13812462083458699
et149824620833456
al.15722462083324760
A1651246208341
Meta-Analysis171024620835489112144167208246279294326353368394
of212224620833757
Trabecular21972462083325083122157190228243275297
Bone251224620833574112147
Score267724620833365102124158
in285324620831552
Fracture4252562083325285117141179200235
Risk6752562083355177107
Prediction7972562083355690129145177201216254292
and110525620833270109
Its12292562083153765
Relationship13092562083357086118140155193232258296311350
to167425620832259
FRAX.174825620833368110151165
J1928256208324
Bone196825620833573112147
Miner213025620835570108143164
Res.23092562083367198111
2016;31(5):940-8.243625620833468100131143178209224258276288323359395419455468
6.42526600853651
Rosen49026610833573100135173
T,67626610833241
Wiren7302661083587495129167
L,91026610833145
Wilhelmsen9682661083577388126161176234260295333
L,131426610833145
et137226610833456
al.14412661083324760
Decreased151426610834580113134168200226261301
psychological18272661083396698130167206222260299314346379394
well-being223426610835085100115138178213228266305
in255226610831452
adult261726610833271108124146
patients277626610833871931084252761083347294121
with5622761083506688126
growth7042761083385996147172210
hormone9292761083387698156195233268
deficiency.12122761083387391108140155190228260293303
ClinEndocrinol(Oxf).15312761083405570108141179218256289310325363402418436483514535559570
1994;40(1):111-6.21172761083346499135147182218237269283295325353380399436449
7.42528600853645
Arwert48728620834162116150171196
LI,7002862083314759
Deijen7762862083468196111146184
JB,9772862083246073
Muller106728620835592108123158179
M,126328620835468
et134828620833456
al.14212862083324760
Long-term149828620833269107146169191225246305
growth18202862083385996147172210
hormone20472862083377697156194233267
treatment23322862083214377109130188223262283
preserves26322862083396094121156177212246273
GH-induced42529620834489111127165204242274308347
memory78829620835792150189210244
and104829620833270109
mood117329620835796134174
improvements:136329620831472111133170202236294329367389417429
a1808296208332
10-year18562962083346589121155187208
follow-up2080296208318567287125176199237277
study23722962083275088127159
in254729620831452
GH-deficient2615296208344881111521862042212532684253062083347294
adult53430620833271108124146
men.69530620835893131144
HormBehav.85430620834583104163199234272305336346
2005;47(3):343-9.121530620833569105139150184216233266284295331366399420455466
8.42531600853651
Touskova48931610833266104130159197228261
V,76231610833645
Klouckova8193161083355189127159188226257290
J,112131610832436
Durovcova117031610834583104141172204240272304
V,148731610833644
et154431610833456
al.16123161083324760
The168431610833372106
possible180331610833877103130144183199233
role20493161083205773107
of216931610833756
mRNA223831610835793138179
expression242931610833465105126160186212227265303
changes27443161083326910113942532610833873100
of54532610833756
GH/IGF-1/insulin62232610834388114130174207229260281297335362399414429467
axis11093261083326379105
components123432610833168127166205243278316338365
in162032610831452
subcutaneous169232610832664103135173196229267302340378405
adipose21173261083327186125164190225
tissue2363326108321376389126161
in254432610831553
metabolic261732610835793115148187226242257289
disturbances4253362083385379103140162201234272304338365
of80533620833857
patients8773362083397294109144182203231
with11233362083516689127
acromegaly.12653362083326485123181216256288303335345
Physiological162533620833673104131145183199237277292324357372
research.20133362083205481116148169200238251
2016;65(3):493-503.228033620833468100131143179213231264281293328361394415449484517529
9.42534600853649
Conway49334620834077115166199229
GS,7413462083437689
Szarras-Czapnik8483462083336195116138171197218261292325364403418448
M,131434620835468
et140034620833456
al.14743462083324760
Treatment15523462083335084116138196231269290
for18613462083185677
24195634620833466
months204034620835896134156194220
with22783462083516789127
recombinant24233462083215588125183222238276308346367
human28083462083387642535620835790128
GH56735620834388
has6693562083377096
a779356208332
beneficial82535620833874112147165182214229261276
effect11153562083345473107140164
on129335620833775
bone138235620833978116151
mineral154735620835772110145166199215
density177635620833873111137152174208
in199835620831553
young206435620833169107145184
adults226235620833271108124146174
with24493562083516789127
childhood-25903562083316984100138177215253293315
-onset4253662083216199125160183
GH62336620834488
deficiency.7273662083387390107139154189227259293303
EurJ10453662083336990113
Endocrinol.117336620833371110148181202217255294309322
2009;160(6):899-907.151136620833468104139152182213249268302320332366401436460495530563569
10.4253760085367085
Elbornsson5233762083334887125147186212239277315
M,85237620835468
Gotherstrom93337620834482104142177199226249270308366
G,131237620834457
Franco13833762083325285123155192
C,158837620834053
et165437620833457
al.17243762083324760
Effects17973762083335271105138162190
of200037620833756
3-year20703762083345688122154175
GH225837620834489
replacement23603762083215594110142174208266301339361
therapy2734376208322609511614942538620833970
on51038620833876
bone60238620833877115150
mineral76838620835772110145166199215
density99838620833873111138153175209
in122238620831553
younger129038620833169107145184219240
and154538620833270109
elderly16703862083334988123144160192
adults187738620833271109124146174
with20663862083516789127
adult-onset220938620833170108123146165205243270305327
GH255238620834388
deficiency.265538620833973911081401551902284253962083316575
EurJEndocrinol.5153962083336990113146184223261294315331369407423436
2012;166(2):181-9.96639620833468100130142172204239258292310322352383415433468479
11.4254061085366678
Rota5194062083357496128
F,66240620833339
Savanelli7164062083326597130168203218233248
MC,97940620835595108
Tauchmanova11024062083336199131169226259297335367400
L,151740620833145
et157740620833456
al.16484062083324861
Bone172440620833573112147
density188640620833873111137152175208
and210940620833270109
turnover22334062083226081120158190224245
in249340620831553
young256140620833168106144184
adult276040620833170108123146
patients4254161083397293109143181203230
with6684161083516689127
growth8084161083385996147172210
hormone10314161083377697156194232267
deficiency13114161083387391108140155189227260293
after16174161083325176109130
2-year17604161083355587121153174
growth19474161083385996147172210
hormone21704161083377697156194232267
replacement24504161083215594110142174208266301339360
according2823416108332644254261083316890128143181220
with6604261083516689127
gender.80242610833873111150185207217
J1034426108324
EndocrinolInvest.107442610833270109147180201217255293309324362393428454478491
2008;31(2):94-102.158042610833469105140152187218233267285297332368391422453486499
12.4254360085366884
Krantz5274362083355790128150181
E,72543620833346
Trimpou7894362083335065123162201239
P,104643620833540
Landin-Wilhelmsen110443620833164102142157195217275291306344379394452479514552
K.167343620833551
Effect17414362083335271105138162
of192143620833757
Growth199543620834466103154179217
Hormone223043620834482104162200239274
Treatment25224362083324983115137195230268290
on283043620833775
Fractures4254462083325285117141179200235261
and70244620833270109
Quality82744620834785118133148170204
of104744620833757
Life11204462083314666100
in123644620831553
Postmenopausal13044462083367299122180215254292331364402428461477
Osteoporosis:17974462083477497131169209248269307333348374387
A2200446208341
10-Year22574462083346589122153185206
Follow-Up24794462083327085101139190212258296
Study.279144620833354924254562083387080
J520456208325
Clin5604562083405570108
Endocrinol68345620833370110148180202217255293309
Metab.100845620835489112144184196
2015;100(9):3251-9.121945620833569100130141171203239258291309321356389423455473508519
13.4254660085366883
Mo52546620835493
D,63546620834556
Fleseriu7084662083334782109144165181218
M,94346620835568
Qi102846620834763
R,110846620833549
Jia11744662083254072
N,126346620834457
et133746620833457
al.14114662083314760
Fracture14884662083325285117141179200234
risk1739466208321376393
in184946620831452
adult191846620833271109124146
patients20824662083387193108143181203230
treated23294662083224377109131165204
with25504662083516789127
growth26944662083386097148172211
hormone4254762083387697156194233268
replacement7094762083215594110142175208266301339361
therapy10874762083216095116149188219
for13234762083185678
growth14174762083386097148173211
hormone16454762083377597155194232267
deficiency:19294762083387390107139155189227260293307
a2252476208332
prospective23014762083396097124163199231255271303338
observational2655476208338771041391601952284254862083223775113146161
cohort60148620833269107145167192
study.8084862083264987126158168
Lancet99148620833265103135169191
Diabetes11984862083456193132167190223250
Endocrinol.146448620833270109147180201217255293309322
2015;3(5):331-8.180148620833468100130141176194228246258293326357376411425
14.4254960085367187
Appelman-Dijkstra53449610834182123160176236269309332381397413445475499522556
NM,1112496108345102116
Claessen12514961083405690126154182218258
KM,153149610833593108
Hamdy166149610834578138178211
NA,189549610834587103
et202049610833458
al.21004961083324963
Effects21854961083335372108142167196
of240349610833858
up248449610833778
to258449610832260
15266749610833465
years275549610833166100122150
of42550610833758
recombinant5055061083215689127187227243282316355377
human90450610833877136169208
GH113450610834490
(rhGH)12465061083193979124170190
replacement14585061083215696113146180214273309349371
on185150610833877
bone195050610833979118155
metabolism212750610835793117150191231247263290349
in249850610831554
adults257450610833272111127150179
with27755061083516791130
growth4255161083396199152178217
hormone66451610833878101161200240276
deficiency9635161083387493110143159195235268303
(GHD):128851610831963109156175188
the14985161083226298
Leiden16185161083326884124160199
Cohort184051610834078118158180206
Study.20695161083325594134167178
Clin22705161083405672111
Endocrinol240451610833372112152186208225264303320
(Oxf).27475161083186699121146158
2014;81(5):727-35.42552610833469101133146182214230264283296330365399418451485497
15.4255360085366883
Barake5215362083356889122153187
M,72153620835568
Klibanski8025362083355267106139177203233250
A,106553620834155
Tritos1133536208333506688125152
NA.129853620834586101
Effects14125362083335271105138162190
of161553620833757
recombinant16855362083215587124183222237275308346367
human206553620833876133166204
growth22825362083385997148172210
hormone25065362083377697156194232267
therapy278753620832160954255462083215493124
on56554620833876
bone65754620833978116151
mineral82454620835873111146167200215
density105654620833873111137152174208
in128054620831553
adults134954620833271108124146174
with15395462083516689127
growth16825462083385997148172210
hormone19095462083377597155194232267
deficiency:21925462083397391108140155190228260294307
a2515546208332
meta-analysis.256354620835893115148170203241273288320425556208326416781
J521556208324
Clin5605562083405670108
Endocrinol68455620833270109147180201217255293309
Metab.100855620835590112145184197
2014;99(3):852-60.122055620833468100131143178214233266284295330364397418455490503
16.4255660085367086
Amato532566108341100133155192
G,74556610834458
Carella8245661083407395129145160193
C,103856610834053
Fazio11125661083326292108147
S,127956610833346
et134656610833457
al.14245661083324760
Body150556610833675115147
composition,167356610833269128167207234249272287326365378
bone207156610833979118153
metabolism,224556610835893116149189228244259286344357
and262356610833270110
heart275456610833773105127152
structure4255761083264971109141165203224258
and69857610833270109
function8215761083195795127152167205243
in107957610831452
growth11465761083385996147172210
hormone13715761083377597155194232267
(GH)-deficient165357610831861106125147188223240257289304339377399
adults206657610833271109124146174
before22545761083397594131153187
and245657610833169108
after25795761083325176109131
GH272457610834489
replacement2827576108321554255862083395587119153211246284305
therapy7465862083215994116149188219
at98058620833254
low104958620831553104
doses.116958620833876103138164178
J1362586208324
ClinEndocrinolMetab.14025862083405570108141179218256289310325363402418472508530563602614
1993;77(6):1671-6.20325862083346499132144176211227261279291320352384417436473486
17.4255960085366776
Degerblad51459610834580120154175215230262301
M,82859610835468
Bengtsson90859610833671108147170197224262300
BA,12215961083357690
Bramnert13235961083365790147185220241265
M,160159610835468
et168159610833456
al.17505961083324760
Reduced182359610833570109146178212251
bone208759610833877115150
mineral225059610835772109144165198213
density247659610833873111137151174207
in269659610831552
adults27615961083327110812342560610832249
with4916061083506688126
growth6346061083385996147172210
hormone8606061083387698156195233268
(GH)114460610831962106125
deficiency:12866061083387390107139154189227259293306
increased16096061083145284105140171198233272
bone189860610833877116151
turnover20656061083226081119158190224245
during23266061083397697113151190
12253260610833464
months261260610835896135156194221
of284960610833756
GH42561620834489
substitution52961620832663102129152167190228250266304342
therapy.8876162083215994116149188219229
EurJ11316162083336991113
Endocrinol.125961620833371110148181202218255294310323
1995;133(2):180-8.159761620833464100134144175204237256289307319349380415439475489
18.4256260085366985
Jorgensen5256262083246284122157195221256295
AP,8346262083417781
Fougner93062620833269107147185220241
KJ,11856262083356375
Ueland12756262083447894126164203
T,149362620833241
et154962620833456
al.16196262083324760
Favorable16946262083326293131152185225240275
long-term19846262083155391130153175209230288
effects22876262083345372107139164191
of249362620833756
growth25646262083385996147172210
hormone2789626208337759742563620835796134169
replacement6116362083215594110142174208266301339361
therapy9896362083215994116149188219
on122563620833776
quality131863620833875108123138161194
of152963620833857
life,160363620831530498395
bone171563620833978116151
metabolism,188363620835893115148187226242257283340353
body225363620833978117149
composition241963620833168127166205231246269284322360
and279663620833270109
lipid425646108315317187126
levels5736461083155083118135161
in75564610831554
patients8306461083407396112147186208237
with10886461083516790130
adult-onset123964610833272110126149170210249276312335
growth15956461083396199151176216
hormone18326461083387799159198238273
deficiency.21276461083387492109142158193232265300310
Growth245864610834567105157182222
HormIGFRes.27016461083458410616618242565610834477112147174187
2011;21(2):69-75.62865610833468100127135170202217251269281316350374405438450
19.4256660085366982
Elbornsson5226662083334887125147186212239277315
M,85266620835468
Gotherstrom93466620834483105143178199226249271308366
G,131566620834357
Bosaeus138666620833674101134169207233
I,163366620831528
et167566620833457
al.17466662083324760
Fifteen1821666208332476691125160198
years20346662083316597118145
of219466620833756
GH226566620834388
replacement23686662083205494110142174208266301339360
increases274366620831452841061404256762083325893120
bone55967620833978116151
mineral72467620835873111146167200215
density95467620833873111137152174208
in117667620831553
hypopituitary124367620833768108147186202224262278300333354388
patients16456762083397294109144182203231
with18906762083516689127
adult-onset203167620833271108124146166205244270305328
GH237367620834388
deficiency.24756762083397391108140155190228260294304
EurJ27936762083326990112
Endocrinol.42568620833370109148180202217255293309322
2012;166(5):787-95.76368620833468100129142172203239258291310321355388421440475509521
20.4256960085357084
Davidson52169610834475106121158184221258
P,79169610833438
Milne8416961083536882119152
R,100569610833548
Chase106469610833976107133167
D,124269610834555
et130869610833455
al.13756961083314557
Growth144469610834364100149173210
hormone16656961083377495151189226260
replacement19366961083205391106137168201257291328349
in229669610831451
adults235969610833169105120141168
and253869610833168106
bone265669610833775112146
mineral2814696108356704257061083377293125141
density:57870610833873110136151173206220
a810706108332
systematic8557061083255884107141198230251266298
review11667061083205486101136186
and136570610833269108
meta-analysis.148570610835792114147169201238270285317343358384397
ClinEndocrinol(Oxf).18957061083395469107139177215253286306322359397413431477509529553564
2004;60(1):92-8.247170610833468104140151187222241272287298333366386421435
21.4257160085367082
Clanget5227161083405587125164199222
C,75971610834053
Seck82771610833368100130
T,97371610833241
Hinke10307161083445997127161
V,120771610833544
et126671610833457
al.13387161083324760
Effects14137161083335271105138162190
of161871610833857
61690716108334
years17407161083316597118145
of190171610833756
growth19737161083385996147172210
hormone21987161083387698156194233268
(GH)248171610831962106125
treatment26227161083214377109130189224262283
on42572620833776
bone51672620833978116151
mineral68272620835873111146167200215
density91372620833873111137152174208
in113672620831553
GH-deficient120472620834489111152187204221253268303341363
adults.158272620833271108124146174187
ClinEndocrinol(Oxf).17857262083405570108141179218256289310325363402418436483514535559570
2001;55(1):93-9.237172620833468104136144179212229261275287322355377412423
22.4257360085367288
Biermasz5267362083355185107165197224253
NR,7937362083448094
Hamdy90073620834477135174206
NA,111973620834486100
Janssen12327362083245694121147182220
YJ,14657362083365668
et154773620833456
al.16167362083324760
Additional168973620834179118134156171209248280295
beneficial199873620833874112147164181213229261276
effects22877362083345473107140164191
of249273620833756
alendronate25617362083324782120159181218256289310344
in42574620831553
growth4927462083385997148172210
hormone7177462083377697156194233268
(GH)-deficient99974620831961106125148188223241257290305339377399
adults141274620833271109124147174
with16017462083506688127
osteoporosis17427462083376487121160199238260297324338365
receiving21217462083215588121136169185223262
long-term23977462083155392131153175209230289
recombinant270074620832155881241834257562083395492124162184
human62575620833775133165203
GH84475620834489
replacement9487562083215594110142175208266301339361
therapy:13257562083216095116149188219233
a1574756208331
randomized16217562083215492131169228243272306345
controlled198275620833168107128150187203218253292
trial.2290756208322435991106119
J2425756208324
ClinEndocrinolMetab.2465756208340557010814117921825628931032636440241842576620835490112145184196
2001;86(7):3079-85.63776620833468104136144179215234268288300335369402435459495529541
23.30471160085367287
Kuzma314811620833572101160192
M,335411620835467
Kuzmova343511620833572101160198230263
Z,371111620833851
Zelinkova37761162083387187102140170207239272
Z,406211620833751
et412611620833456
al.41961162083314760
Impact426911620831573112145177201
of448411620833756
the45541162083216095
growth46621162083385997148172210
hormone48861162083377697156194232267
replacement51671162083215594110142174208266301339360
on304712610833776
bone314412610833978117152
status33171261083265083105143170
in350712610831553
growth35811261083386097149174212
hormone38141261083387698157196235270
deficient41051261083387391108140156191229251
adults.437712610833271109125147175189
Growth458712610834465103155179218
hormone48261261083377698157196234270
&5108126108340
IGF51601261083156093
research:52741261083215582118150171203241253
official3047136108337567491124139171186
journal32481361083155391112151183198
of346113610833757
the35331361083215994
Growth364213610834465103154178216
Hormone387313610834483104163201239274
Research41621361083367197132164185216254
Society443113610833371104119154176210
and465513610833270109
the47791361083226095
International48881361083155375109130168201222238276314346362
IGF52651361083145992
Research5372136108335709713230471462083325384122
Society.318414620833371104119154176210220
2014;24(1):22-8.341914620833468100131143178210229261275287322357377413427
24.30471560085367186
Joseph31501562083246289124163202
F,336915620833238
Ahmad342415620834180137170209
AM,365015620834196110
Ul-Haq37771562083445981127159198
M,399215620835568
et407715620833457
al.41511562083324760
Effects42281562083335271105138162189
of443515620833756
growth45081562083385997148172210
hormone47361562083377597155194232267
administration502015620833271129144182197223246268301323338376414
on545115620833876
bone304716620833977116151
mineral321116620835773110145167200215
metabolism,343916620835893115148187226242257283340353
PTH380516620833569115
sensitivity39331662083266199126140163178211226249283
and422916620833270109
PTH435116620833569114
secretory44791662083266193115149171208230264
rhythm47561662083205990114153210
in498016620831452
postmenopausal504516620833978104128186221259297337370407434467482
women304717620835188147182220
with32821762083516689127
established34241762083346184117156172187213251286325
osteoporosis.37651762083376487121159199238259297323338364378
J4158176208324
Bone419817620833573112147
Miner436017620835570108143164
Res.45401762083357097110
2008;23(5):721-9.466617620833468104139152187221239273291303337371402421456467
25.30471860085357185
Bereket31441861083356990123152185207
A,336318610834054
Cesur34291861083397298134155
Y,359618610833442
Ozkan365018610834675105138175
B,383718610833447
et389618610833355
al.39631861083314658
Circulating40331861083395474105141156187208223260298
insulin-like43431861083155177113128142179201217231260293
growth46481861083385895145168206
factor48661861083185081105141162
binding50401861083385390128142179217
protein-452691861083385995117149164201223258
(IGFBP-4)30471961083193478111146182203240257
is331919610831541
not33751961083387698
regulated34881961083215594132147180201235275
by377819610833870
parathyroid38631961083397293126147186216238275291330
hormone42081961083377697156194233268
and449119610833270109
vitamin46151961083314770102160175213
D4843196108346
in490419610831552
vivo:49721961083314780117129
evidence51171961083346682120155193226259
from53911961083194178136
children3047206108331688398136157190228
with32872061083506587125
rickets.3424206108321366897131153180193
Journal362920610832462100120158190205
of384620610833756
clinical3915206108331456097112143176191
research41182061083215480115146167197235
in436520610831552
pediatric442920610833974113127159180201216248
endocrinology.468920610833471110147179200215253290306343382414424
2010;2(1):17-20.51252061083346799130142176193225239250279308326357390403
26.30472160085367187
Soliman31502161083327187102159192230
AT,33952161083417079
Al349021610834156
Khalaf356221610833574107122154173
F,375121610833238
Alhemaidi38052161083415694129187220235274289
N,410921610834558
et418321610833456
al.42552161083314760
Linear43312161083314684119151172
growth45192161083385996147172210
in474521610831553
relation48132161083215571103125140178216
to504521610832259
the51192161083226095
circulating5230216108331466798136151184205221259298
concentrations304722610833168106139172210232253286308323361399426
of348622610833756
insulin-like35552261083155379116131146184206223238268302
growth38702261083385996147172210
factor40932261083185184108144166
I,427222610831527
parathyroid43122261083397293126148186216238276291330
hormone,46552261083377697155194232267279
and494722610833270109
25-hydroxy50692261083346991130160199220257287321
vitamin54032261083314770102304723610835772110
D3174236108345
in323623610831552
children33052361083316984100139160194232
with35542361083506688126
nutritional36972361083377598119135157172210249281297
rickets4010236108321366898133155183
before42092361083397494131153187
and441323610833169108
after45382361083325176110131
treatment:46852361083224478109131189224262284297
endocrine499923610833472111149182203219257292
adaptation53072361083327110414316519830472462083223775113
to317624620832158
vitamin32502462083314769102160175213
D3478246208346
deficiency.35392462083387391108140155189227260293303
Metabolism.385724620835590112145184223239254280338351
2008;57(1):95-102.422324620833469105140152187221237269283295330364387417449482494
27.30472560085367079
Gomez313925610834382140175204
JM,33562561083247891
Maravall346025610835487107140171204219234
FJ,37072561083325163
Gomez378325610834382140174204
N,399925610834557
et406925610833456
al.41382561083314659
Relationship42102561083357085117139154191230256293308347
between45702561083387395148182217255
25-(OH)48382561083346990110156201220
D3,50702561083457890
the51722561083226094
IGF-I52792561083155992113129
system,54212561083265885304726610832255113126
leptin,31912661083154989111126164177
anthropometric33852661083327092130151188228267325360382404419451
and385426610833270109
body398126610833877117149
composition414726610833168127166205231246269284322360
variables45252661083326586101133173189223250
in479326610831552
a4863266108332
healthy,491326610833772104119142180211220
randomly51512661083215492131169227243274
selected54432661083266130472762083155082106140180
population.324727620833877117155170203224240278316329
Hormone359627620834483104163201240275
and389127620833169108
metabolic401927620835893115148187226242257289
research43282762083205581116148169200238
=4586276208342
Hormon-464827620834483104163201239262
und493027620833775114
Stoffwechselforschung5064276208333549111012918321825028831535036538442244430472862083265896134172211
=3273286208342
Hormones333028620834483104163201240275301
et364728620833456
metabolisme.371828620835893115148187226242257283340375388
2004;36(1):48-53.412128620833468104141152187222241273287299333369392426459471
28.30472960085367288
Bogazzi315129620833574113146175206222
F,338929620833238
Rossi344229620833674101127142
G,360029620834357
Lombardi367229620833269127167200221259274
M,396229620835468
et404529620833456
al.41172962083324760
Vitamin41922962083365375108166181219
D4426296208345
status44872962083264982104142168
may467129620835789120
contribute480729620833168106128149165204242265298
to512129620832259
serum51952962083266182121179
insulin-like538929620831553791163047306108315306890106121151185
growth32453061083385997148172210
factor34683061083195284108145167
I3648306108314
concentrations367530610833268107139173211232253286308323361400426
in411430610831552
healthy417930610833873105120142180211
subjects.440330610832663102118153185209237250
Journal466630610832563101122161193208
of488730610833757
endocrinological495730610833472111149181203218256294310348388403435467483
investigation.54533061083145230473161083326693116131170202224239277316329
2011;34(8):e200-3.339131610833469100128136171207226260278290324359393429453485498
29.30473260085367387
Halupczok-Zyla31553261083457894132172205236274306327363394410443
J,361932610832537
Jawiarczyk-Przybylowska367732610832557109125158179211243277309329367388420454495527543582634662692726
A,442532610834156
Bolanowski45023261083357591124163202254281312329
M.485232610835569
Patients49423261083366991107142181203231
with51943261083526891130
Active53453261083417398114147182
Acromegaly30473361083417294131189224264296311343
are34033361083325387
at350333610833254
High35703361083445998136
Risk37193361083355177107
of383933610833756
25(OH)D39093361083346986133178197242
Deficiency.41643361083468198115147163197235268301311
Frontiers44883361083325289128149165199221248
in474933610831452
endocrinology.481433610833472112150182204219257295311349389421431
2015;6:89.525833610833468100130141177189224258269
30.30473460085367287
Ameri314934620834199134155171
P,333434620833540
Giusti33883462083445997123146162
A,356434620834155
Boschetti363334620833674101133171206228253268
M,391534620835568
et399834620833456
al.40683462083324760
Vitamin41433462083355274107165180218
D4375346208345
increases44353462083145284106140172198233260
circulating4709346208332476899137152184206221259298
IGF150213462083156093124
in516034620831452
adults:522734620833170108123146173186
potential54273462083397830473562083225593115130162178
implication324135620831472111127142174207229244282321
for35783562083185677
the36713562083226095
treatment37823562083224378109131189224262284
of408235620833757
GH415535620834488
deficiency.42603562083387390107139154189227259293303
European45793562083326990127167202234272
journal48683562083155391112150183198
of508235620833857
endocrinology515535620833472111149182203219257295311349304736620833870
/3132366208325
European31723662083337091128167203235273
Federation346036620833367106141162195217232270309
of378436620833757
Endocrine385636620833370109148180202217255290
Societies.416136620833371104119154176191226253266
2013;169(6):767-72.444336620833468100130141171202236255289307319352384417435467501513
31.30473760085366981
Kuzma314837620833572101160192
M,336037620835467
Binkley34473762083355188119135170202
N,366837620834558
Bednarova374537620833571110148180202239271304
A,406837620834155
et414337620833456
al.42183762083324860
Trabecular42983762083325083122157190228243275297
Bone461437620833574112147
Score478137620833265101123157
Change495837620833977110148187222
Differs51993762083456181100134155182
with54013762083506688127
Regard304738620833570110142163201
to326238620832259
25(Oh)D33343862083356987133172189235
Levels35833862083316598132147173
in377038620831553
Patients38363862083356789104139177199226
Treated40763862083335084116137171211
for43003862083195678
Adult-Onset439238620834179116132154174224262289324346
Growth475238620834365102153178216
Hormone498238620834482104162200239274
Deficiency.5270386208345809811514716219723530473961083316575
Endocrine313539610833270109147180201217254289
practice34373961083396194126150165197231
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official3706396108337567491123138170186
journal39053961083155391112151183198
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the41863961083215994
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College45803961083407793108143182217
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Endocrinology487939610833371110148181202217255293309347387419
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the54333961083216095
American304740610834199134155171203236274
Association33364061083416995134166181213235251288327
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Clinical37504061083405570108123155188203
Endocrinologists.396940610833270109147180201217255293309347387402428451479492
2016;22(8):951-8.447740610833468100131143178213230264282294329363394413449462
32.30474160085367186
Vestergaard31514162083366895118152173211244276297335
P,350341620833540
Mosekilde356041620835593120155185201216255290
L.386741620833245
Fracture39294162083335285118142180201235
risk4181416208321366292
is429041620831541
decreased434841620833873106127161193219254294
in465941620831552
acromegaly--a47284162083326486123181216256288303335357381413
potential51584162083397799133171193208240255
beneficial54304162083397530474262083387390107139154186202
effect32674262083345473107140164
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growth35254262083385997148172210
hormone.37544262083387698156194233268280
Osteoporosis40534262083477497131169209248269307333348374
international44464262083155374108129168200222237275313346361
:4826426208312
a4857426208332
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as546942620833258
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cooperation329143620833168107146182203236258273311350
between36564362083397497150184220258
the39294362083226095
European40394362083337091128168203235273
Foundation432743620833370108146185218239255293331
for46744362083185677
Osteoporosis47674362083477497131169209248269306333348374
and515743620833169108
the52814362083226095
National53914362083457799114304744620833776108123
Osteoporosis31864462083477497131169209248269307333348374
Foundation357644620833269107145184217238254292330
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the39934462083226095
USA.410444620834375116131
2004;15(2):155-9.425044620833468104141153183213230264282294324354386408443454
33.30474560085367186
Riggs31534562083355190129155
BL,33284562083366881
Randall343045620833568106145177192208
RV,36584562083357281
Wahner375945620835789127165200221
HW,4000456208344102112
et413245620833457
al.42094562083324760
The428945620833372107
nature44174562083376991129150184
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the46984562083226095
metabolic481445620835792114147186225241256288
bone512245620833978116151
disorder52934562083385480118140178213234
in304746620831553
acromegaly.31154662083326485122181216255287303335345
The347546620833372107
Journal359746620832463101122160193208
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clinical38924662083324762100115147180195
endocrinology410246620833472111150182204219257295311349389421
and453846620833270109
metabolism.466246620835893115148187226242257283341354
1972;34(6):911-8.50314662083346597132144179215234267285297332364392411447460
34.30474760085367388
Kayath31484761083356899132153191
MJ,33524761083548092
Vieira34574761083355286101122155
JG.36254761083246882
Osteopenia37204761083477497130169208243281296328
occurs406147610833770100138159186
in426047610831452
a4325476108332
minority436947610835873110148170185208241
of462347610833756
patients46924761083397193108143181202230
with49344761083516689127
acromegaly50734761083326485122180215254287302333
and541947610833270109
is304748610831541
predominant31014861083396195134172231246284316354375
in349048610831553
the35564861083226095
spine.36654861083266580118153165
Osteoporosis38444861083477497131169209248269307333348374
international42324861083155274108129168200222237275313346361
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a4632486108332
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European38054962083326990127167203234272
Foundation409649620833270108146185217239254292331
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the50624962083226095
National51764962083447798114152190222238
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Foundation336150620833370108146185217239255293331
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USA.388950620834476117132
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35.30475160085367186
Bonadonna314751620833574112145184222260298331
S,349251620833345
Mazziotti355251620835487117148163201223248263
G,383051620834357
Nuzzo390151620834583112143181
M,409651620835568
et417951620833456
al.42505162083314760
Increased43245162083155385107141172199234274
prevalence46125162083396094127160175210248280314
of494051620833857
radiological50125162083205392108145161200239254286319334
spinal53615162083266581119151166
deformities30475261083387493131153212227250265300327
in339552610831453
active34685261083326589105137172
acromegaly:36615261083326486123182217257290305337351
a4033526108332
cross-sectional40855261083325391118145166193228261286301339378411426
study45325261083265088127160
in471252610831553
postmenopausal478652610833978105128187222261299339372410437470486
women.529352610835088147183221234
Journal304753610832463101122161194209
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bone335453610833978117152
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mineral365653610835873111146168201216
research38935361083215582117149170202240
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American492353610834199135156172204237275
Society521953610833271104119154176210
for54505361083185678
Bone304754610833574112147
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Mineral333454610835470108143164197212
Research.35615461083367198133165186217255268
2005;20(10):1837-44.384454610833469105139150185219238270301320332361392426459477514551563
36.30475560085367288
Mazziotti315655610835587117148164202224248264
G,344055610834458
Bianchi35185561083365183121153192207
A,374555610834155
Porcelli38215561083357294125159174189204
T,404655610833342
et410855610833456
al.41855561083324760
Vertebral42665561083356890114148188209242258
fractures45445561083194174106131169190224251
in481555610831553
patients48895561083387193109143182203231
with51415561083506688127
acromegaly:5288556108332648612318221730475661083387086118131
a3195566108332
3-year32445661083345688122154175
prospective34365661083396098124163199232256271303338
study.37915661083264987126158168
The397656610833372107
Journal410056610832462100122160193208
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clinical4399566108331466199114146179194
endocrinology461056610833472111150182203219257295311349389421
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metabolism.517456610835792115147187225241256282340353
2013;98(8):3402-10.304757620833468100130141177212231264283294330365401434454485517529
37.30475860085367079
Claessen31455862083405587122149176211249
KM,341258620833592105
Kroon35365862083345794133171
HM,372658620834499112
Pereira38575862083356889124139160193
AM,406858620834197110
et419758620833456
al.42715862083324760
Progression43505862083355693132153188214241256294332
of470158620833756
vertebral47765862083316587111145184206239254
fractures50495862083184073105129167189223249
despite531758620833873100139154177210
long-term30475962083155391130153175209230289
biochemical33535962083385492125163197255271302335351
control372159620833168106128149187203
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acromegaly:40145962083326485123181216256288303335349
a4380596208331
prospective44285962083396198125164199232256271304338
follow-up4783596208318567287125176199237277
study.50775962083264987126158168
The526259620833272107
Journal53865962083246210012230476062083387085
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clinical32196062083324762100115147180195
endocrinology342960620833472111150182204219257295311349389421
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2013;98(12):4808-15.435860620833469100130142177212231263293311323357393428464486517547559
38.30476160085367288
Ueland31526162083447894126164203
T,337261620833241
Bollerslev34306162083357490105140161188203238270
J,371761620832436
Godang377061620834382122154192231
K,401861620833549
et408461620833456
al.41576162083314760
Increased42336162083155385106141172199234273
serum45236162083266182121179
osteoprotegerin47186162083376487121160199221258280314353388409425463
in519761620831553
disorders52676162083385379117139177212233260
characterized304762620833169102123156188212246267283312346385
by344662620833870
persistent35296262083397596123138164187221259280
immune382362620831572130168206241
activation40776262083326489104136169191206244283
or437362620833859
glucocorticoid44466262083385391123160192229251276291323360375414
excess--possible48746262083346596130157183204228268307333360375414430465
role53526262083215874109
in547562620831452
bone304763620833977116151
homeostasis.321363620833876134169208235258291317332358372
European36006362083336990128167203235273
journal38886362083155391112151183199
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endocrinology.417463620833472111149182203219257295311349388421431
2001;145(6):685-90.462063620833468104136144174205238256289307319355390424446481517529
39.30476461085367183
Stepan31476462083325386124157194
J,335764620832436
Marek340964620835486107140170
J,359564620832435
Havranek364764620834475106128160197231261
T,392464620833341
et398164620833456
al.40536462083324659
Bone412864620833573111145
isoenzyme42896462083154078113150179212270304
of461064620833755
serum46826462083266081118175
alkaline48746462083314675108123137174208
phosphatase509964620833876114140178216247268301326361
in547664620831552
acromegaly.30476561083316282118175208246277291322331
Clinica33896561083395367103117148179
chimica35796561083316882138152182214
acta;38046561083316285116127
international39426561083145171104124161192212226263300331345
journal42986561083155188108145176190
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clinical4565656108331455995109140171185
chemistry.476165610833168101157171196218238271280
1979;93(3):355-63.50526561083346294126138172203220252268279313344375396432464476
40.30476660085367489
Scillitani3153666108332658095110125148180218233
A,340466610834155
Chiodini34766661083407893131170186223238
I,373266610831427
Carnevale37766661083407394133168200233249283
V,407766610833544
et413866610833457
al.42126661083324760
Skeletal42896661083326297112147169202217
involvement45246661083145284121137170204262297335356
in489866610831452
female496766610831953111143159194
acromegalic51786661083326485122181216255287303318350
subjects:304767620832663102118153185210237250
the33136762083226095
effects34256762083345372107139163191
of363367620833756
growth37066762083385996147172210
hormone39336762083377697156194232267
excess42176762083346597130157184
in441767620831553
amenorrheal448667620833290125163202223245283318350366
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menstruating499467620835792130156180201239272293309347386
patients.5396676208339729410930476862083347294121135
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bone349868620833978116151
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research40256862083205481116148169200238
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the43106862083226095
official4422686208337567492124139171186
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the49156862083226095
American502768620834199134155171203236274
Society531868620833371104119153176209
for30476962083185678
Bone314069620833574112147
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Mineral342769620835470107142164197212
Research.36546962083367198133164186217255268
1997;12(10):1729-36.393769620833464100133142173202220251283301313343372407441464497531545
41.30477060085366981
Mazziotti314770620835487117148163201223248263
G,342970620834457
Biagioli35057062083365183122137175191206
E,373070620833246
Maffezzoni379570620835487106125160189220258296311
F,412570620833338
et418370620833356
al.42587062083324760
Bone433770620833574112147
turnover,45037062083226081120158190224245255
bone477770620833978116151
mineral494770620835873111146167200215
density,518170620833873111138152175209218
and541870620833270109
fracture30477161083184174106130168190224
risk3292716108320366292
in340571610831553
acromegaly:34787161083326486123182217257289304336350
a3849716108331
meta-analysis.390171610835793115148171203241274289321348363389403
The432571610833272107
Journal445271610832563101123161194209
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clinical47597161083324762100115147180196
endocrinology497571610833573112150183205220258297313351391423
and541971610833170109
metabolism.304772610835792115147187226241256282340353
2015;100(2):384-94.341672610833468100130141171202238258292310322357391428451485521534
42.30477360085367086
Maffezzoni314773620835487107126160189221258296312
F,347273620833339
Maddalo352473620835587126165198213251
M,378973620835568
Frara38717362083325285106139
S,402473620833245
et408373620833456
al.41537362083324760
High-resolution-cone42277362083445998136158180214241279295333355371409447469503540579613
beam485473620833974106164
tomography503273620832259117155195216249288327357
analysis5403736208332701023047746108315477489115
of318274610833757
bone325974610833978116151
microarchitecture343174610835772104126163196217248286301324358390415453474508
in395974610831553
patients40327461083397294109144182204231
with42847461083506688127
acromegaly44317461083326485123181216256288303335
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radiological49167461083215493108146162200240255287320335
vertebral52727461083316687112145185206239255
fractures.30477561083184073106130168189223250263
Endocrine.332675610833270109147180201217255290302
2016;54(2):532-42.364375610833469100131144179214233267285297333366398418455488500
43.30477660085367186
Malgo315376620835487102141180
F,335276620833238
Hamdy341076620834476134173205
NAT,363476620834586115124
Papapoulos377776620833667107140179218256271309336
SE,41327662083336578
et422976620833457
al.43057662083324760
Bone438576620833573112147
material455176620835890112145167182214230
strength48007662083264971105143182205243
index50627662083155392127158
as524076620833158
measured53177662083589312415118830477762083215594
by315877620833970
impact324577620831572112145177201
microindentation346377620835772104125163178216255290328350382404419457496
is397677620831441
low403377620831553104
in415477620831553
patients42247762083397293109143181203231
with44727762083506688126
fractures46157762083194174106130168189223250
irrespective4882776208315365792118157193226250265298332
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fracture53047762083194174106130168189223