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HLAVNÍ506722001005185134178232252
TÉMA533422001003981147194
Farmakologická21473300100376892153187222260275314353368398433468
léčba26313300100155182120155
arteriální28023300100345887122147163197213250266
hypertenze308433001003773111147171200235273305339
u3439330010037
starých34923300100285592116154184222
a3730330010034
velmi37803300100357085145160
starých39573300100285591116154184222
nemocných419533001003772132171202240276306343
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současných460533001002968106137172201239275305342
EBM496333001004084146
doporučeních512533001003776114154178217247282319335365403
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LÉKAŘSTVÍ5127804001074184130188235280325378399
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celkové42562001074083103141189230273
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kognice226762001073886137186204245288
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Dostatek779760010758106140168210236279317
času111276001074081114161
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přáním166476001074976117165183256
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pacienta244576001074990131149193240267308
s2770760010733
cílem28207600107405842590001071962135
dosáhnout57690001074997130171219266314362389
shody98290001073380128177217
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terapeutických12729000107287096137186230277305323363401443482530
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něž566104001074892129
je711104001072064
bezpečnější791104001075095132182227269317361379412430
mírnější1238104001077492119167211230263281
pokles1536104001075099137158202236
krevního1788104001073866109150199218268316
tlaku212110400107284787125173
i23111040010719
za2347104001073678
cenu2442104001074083131178
nižší2637104001074967104139157
KV2811104001074594
protekce.425118001075077124151194232271313328
Depreskripci7791180010759103153180223257294322342391432451
však1256118001074174116154
velmi1436118001074184103177195
pečlivě1657118001075095136155173214257
zvažujeme1941118001073680121158207225269343387
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přistupujeme242111800107507796129158206255304322366440484
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pokud343762001074999137185235
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máme3773620010774115188233
dostatek402562001074997131160201228271309
kvalitně435362001073882124143161189238282
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měření5149620010774118143186234253
TK,542162001074288106
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nízké313876001074867103142185
hodnoty334276001074997147195244271314
TK367576001074288
jsou378376001071952100148
spojeny395176001073383132151195243281
se425276001073478
symptomy434976001073475150199227273347386
nebo475576001074892142191
jinými49657600107203886125199218
NÚ5202760010758114
(elektrolytové53357600107246685129167304790001072855102121161193239279323
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kontroly448290001073885134161188235254294
hodnot479790001074997147195244271
TK508990001074288
i5198900010719
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(výskyt3475104001072463107141178221252
a37481040010740
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renálních4959104001072769118158177225244284332
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metabolických30811180010772115142182231279297315354391432471518
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monitorováním40751180010773120167185212257283329368408455473545
celkového463511800107408199136182221263310357
stavu5007118001073361101140187
pacienta.5210118001074889128146189235261302317
PROHLÁŠENÍ48514800974387144199239292335376430452
AUTORŮ:954148009749101143200245299316
Prohlášení128614700984573119166187229263305352373
o1674147009845
původnosti:173514700984693134179227274320354383404423
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byla24981480095447997133
zpracována264714800953378102139176218254291334371
s3034148009529
využitím307914800953775119152169195212277
uvedené337214800954380119163203246286
literatury3674148009517335997121158183226249288
a3978148009536
nebyla403014800954383127163181217
publikována426314800954487132150166200243279316359396
ani46751480095367996
zaslána478714800953270100117153197233
k5036148009534
recenznímu50861480095236299137180213257274340382
řízení4851600095244174113156173
do68116000954487
jiného7911600095173477117161204
média.1018160009566106151168204219
Střet12601590098427099141170
zájmů:145215900983679101169215235
Žádný.170916000954381125168203214
Financování:194615900984161108149196233278318360406428447
Práce241516000954064101137176
ET261416000953777
byla27151600095447997134
podpořena287216000954488133178222246285328364
projektem326016000954468111128167202230268334
NETPHARM361716000955189129170220267308371
/Nové401116000952880124160199
technologie423316000952563100144187230248291336353393
pro464916000954469111
translační47831600095254987130159177213249293309
výzkum511616000953675110144188254
ve539316000953675
farmaceutických4851720095215983150187223261304330347384418456492536
vědách,104417200953675120157194237251
reg.131917200952362107122
Č.146417200954661
CZ.02.01.01/00/22_008/0004607/,1549172009545901051451831972372732833233593844224634915315706126536947357638028438849269671007104410671074
za264617200953371
spolufinancování274017200953074119137179201219263299343379421458495538555
EU.33191720095378799
Poděkování:344217100984590138180223268308350397418437
Ne.390117200955191105
Registrace402917100984688135157191221250291328370
v4421171009841
databázích:448417100984788117159207249286308345391410
N/A.491717200955181123139
Projednání508017100984574120142184232279321367389
etickou4851830098417191128170214261
komisí:76218300984186155176210231250
N/A.102818400955180122139
LITERATURA426211001234978134189250318368438498567
1.42522800853648
Marengoni49222800835487108142180219257296311
A,82122800834156
Angleman89522800834179118134168226259297
S,121022800833345
Melis127422800835489105120146
R,143922800833549
et150622800833457
al.15812280083324760
Aging16602280083417994132171
with18492280083516789127
multimorbidity:199522800835795110132148205244265305320359374397431444
a2458228008331
systematic25082280083265885109142200233254270302
review2828228008321554252380083324782133
of57423800833756
the6452380083226095
literature.756238008314295286107140162200221255267
Ageing103823800834179114130167206
Res12602380083357097
Rev.137223800833671103113
2011;10(4):430-439.150023800833468100128136166198217250268279314346381405441474507518
doi:10.1016/J.ARR.2011.20342380083387691103133165177208239271302327348361404440476491527561593621630
03.26792380083346880
003277423800833571104
2.42524800853651
Guthrie48924800834381104141162178212
B,71424800833547
Payne7742480083356797136170
K,95724800833549
Alderson10192480083415694129150177215253
P,128524800833539
et133724800833456
al.14052480083324760
Adapting147724800834179111150172187225263
clinical1753248008331466198113145178193
guidelines19582480083387690129164179194231266293
to226324800832258
take23342480083225484118
account24652480083316394130168206227
of270524800833756
multimorbidity.2773248008357951104252580083223795133155194210249264286320330
BMJ.77025800833691116129
2012;345(7878).91425800833469100130143178213246263298331364398416427
doi:10.1136/BMJ.E6341.13562580083387692104134165178209236266301326362417443456490524558594624633
3.42526800853651
Shantsila48926800833270102140162189204219252
E,75426800833245
Lip8122680083324786
GYH,91126800834479125137
Shantsila106126800833371103141162190205220252
A,132626800834155
et139426800833456
al.14632680083324760
Antihypertensive153626800834179101116154184224260281305339377403418451485
treatment20342680083214377109130188223261283
in233026800831452
people239526800833974113152168203
of261126800833756
very26802680083326687121
old28142680083385392
age42527800833271106
with5492780083506688126
frailty:694278008318407388103126159173
time8852780083223795130
for10332780083185677
a1128278008332
paradigm11782780083397293126165180219277
shift?1473278008326647998123149
J1640278008324
Hypertens.168227800834476116151172197231269295309
2023200927800833468101136
Oct216327800834779103
1;41(10):1502-1510.22842780083354378108123155186204216246276310343364394424455487499
doi:28022780083387691103
10.1097/HJH.0000000000003495.4252880083346678109140176208228274299344357392428464501537573609645681717753789823858891925937
4.42529800853651
Forman4942980083327091150182220
DE,7322980083457992
Maurer84229800835487124145179201
MS,106129800835487100
Boyd117929800833573105143
C,134029800834053
et141129800833456
al.14852980083324760
Multimorbidity156329800835492107130145203241263302318357372394428
in200929800831452
Older207929800834763102137158
Adults225529800834179117132155182
With24552980083587496134
Cardiovascular260729800834073941321471852172502774253080083316984117138
Disease.5783080083456187122154180215228
J821308008324
Am86030800834199
Coll9753080083407792108
Cardiol.10983080083407394132147185201214
2018;71(19):2149-2161.132730800833468100131143176209224255286304316351382413446470501532564594603
doi:10.1016/j.jacc.2018.19453080083397792104134166178209240272303328345358374406438469482518552584615628
03.25893080083346780
022268430800833467102
5.42531800853651
McDonagh49631800835587133172210243282320
STJ,8373180083326788100
Mejzner95831800835590105135173209230
N,120831800834558
Clark12873180083405588109140
CE.14473180083407386
Prevalence15543180083355690123156171206245277311
of188531800833857
postural196331800833978104128166187220236
hypotension221931800833869109148170204242269284322360
in260031800831553
primary,26733180083396177135167188223232
community42532800833168126183221259274296329
and76732800833270108
institutional8883280083155379102117139177199214252290323338
care:12393280083316384118131
a1382328008332
systematic14273280083265885108142199232253268300
review17403280083205486102137187
and194032800833270109
meta-analysis.206132800835892115147169202239271287318345360386399
BMC247332800833590130
Fam261632800833262119
Pract.27483280083355688120144158
2021;22(1):1-23.42533800833468101133141176211228260274286316334365400413
doi:10.1186/S12875-020-01313-88533380083387692104134165178208236267302327360391421455488520542580613647670708739769800830852888
6.42534800853652
Fialová498348008332478095133166199
D,71734800834657
Laffon7943480083326585104142181
B,99534800833648
Marinkovic,106434800835587109124162193230263278311324
et140834800833457
al.14853480083324861
Medication156634800835590130145177210232248286325
use19113480083376499
in203134800831452
older21043480083375392128149
people227334800833975114154170205
and249834800833270110
age-blind262834800833271106130170186201239278
approach:narrative42535800833271111132169202235272285323355376398431452468500535
literature978358008315305386108141162200222256
review12523580083215587103138189
(insufficient1460358008318337198135153171189221236271309331
evidence18093580083346782121156194226260
on208835800833776
the21823580083226095
efficacy2296358008334527088120153185219
and253435800833169108
safety26613580083266078113135169
of284935800833756
drugs4253680083385997136162
in60036800831553
older6663680083375391126147
age,82636800833271106118
frequent9573680083184074113151186224245
use12153680083376398
of132636800833857
PIMs139636800833549104131
and154036800833169108
polypharmacy,16613680083397893125165203236257315347379413423
and209636800833270109
underuse221836800833775114149170208234269
of250036800833757
highly25703680083375291129144176
bene275936800833874112147
nonpharmacological42537800833877116156195228250309342375413429468508524556590606
strategie).10513780083275173106128163203219254272283
Eur13553780083337092
J1468378008324
Clin15133780083415772110
Pharmacol.164437800833674107129188221254292308321
2019;75(4):451-466.198637800833570102133146179213231264282295330363395414451488524538
doi:25453780083387793106
10.1007/26723780083346679111143180213233
s00228-018-2603-5.4253880083266197130165198221258290321344375408444477499533545
7.42539800853645
Williams4873980083577489104119151209235
B,73939800833548
Mancia80439800835587125158173205
G,102639800834357
Spiering11003980083337187122143158196235
W,135239800835868
et143739800833456
al.15103980083324760
2018158739800833569100131
ESC/ESH173639800833266107134167201245
Guidelines19983980083448297136171187202239274301
for23163980083195678
Themanagement241139800833372107165197235268307341399434472494
of42540800833756
Arterial4944080083416287121142157189204
Hypertension.71140800834476116151172197231269295310348386399
Eur11234080083326990
Heart122640800834479111132156
J1395408008324
2018;39(33):3021-3104.143240800833468100131143178211230263296313325360395427459477510541572608620
doi:20654080083387692104
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8.42541800853652
Mancia49641800835487125157172204
G,72041800834357
Kreutz7964180083355791129152182
R,99841800833549
Brunström10664180083365795133159183204241300
M,138541800835468
et147241800833456
al.15474180083324861
2023162741800833468101136
ESH178241800833366110
Guidelines19114180083448297136171187202240275301
for22324180083185677
the23284180083226095
management244341800835789127160199233291326365386
of284841800833857
arterial4254280083325378111133148180196
hypertension63642800833768108144165189223261288302340379
The103042800833372107
Task11534280083326087116
Force12854280083327091122156
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of206142800833857
arterial21334280083325378112133149181196
hypertension234442800833868108144165190224262288303341379
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European4254380083336990128167203235273
Society71243800833371104119154176210
of93643800833857
Hypertension:100843800834476116151172197231269295310348386398
Endorsed142143800833371110148169197232271
by170743800833970
the17924380083216095
International19014380083155375108130168200222238276314346362
Society227743800833371104119154176210
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Hypertension25734380083447611615117219723126929531042544800833776
(ISH)5184480083193466110129
and66544800833170109
the7914480083226095
European9044480083336990127167203234272
Renal119444800833671109141156
Association13684480083416996134166182214235251289327
(ERA).17134480083185187130149160
J1890448008324
Hypertens.193244800834476116152173198231269296309
2023225944800833468101136
Dec241344800834580113
1;41(12):18742071.2544448008334427710712215418420221424427530833842545800833468101133143
doi:5834580083387692104
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9.42546800853751
Thomopoulos49746800833374113173212253293332348388415
C.93446800834054
Target10094680083346384124160183
blood12134680083405695135176
pressure14104680083406297125152191213248
in167946800831554
isolated1754468008315428298132154189230
systolic20054680083276088112150167182215
hypertension.224246800833869111147169195229269296311350390404
A2667468008342
meta-273046800835995118152175
-analysis4254780083215391124139171198213239
of68447800833757
randomized7614780083215492131169227243272306345
outcome11274780083377598128165224259
trials.1406478008322435991106132146
J1572478008324
Hypertens161747800834476116151173197231269295
2023;41(12):2113-2114.193347800833468101136147182212227259289307319354386413443465496528555586599
doi:25524780083387792104
10.1097/26764780083356679109141176209229
HJH.0000000000003476.42548800834469114127162199235271307343379415451488524560593628660692706
10.4254980085367085
Curtin5264980083407698122138175
D,71849800834556
Gallagher7904980083447792107140179217252273
P,107949800833540
O‘Mahony113549800834760116148186224263294
D.144549800834556
Deprescribing151849800834581120141175202235256271311326364403
in193749800831553
older20064980083385492127149
people217149800833974113153168203
approaching239149800833171110132169202234272287325364
end-277249800833472111133
-of-life:4255080083216180100117132151185198
development63850800833873105139155193232291326364385
and103850800833270109
validation1162508008331647994133166187203241279
of145650800833756
STOPPFrail152750800833267113149184216236269284299
version18415080083326687114129167206
2.206150800833547
Age212350800834179114
Ageing.225250800834079114129167206219
2021;50(2):465471.2485508008335691021331411762102302642822943283643984255180083346699108
doi:5485180083387792104
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11.4255280085366678
Topinková52152800833367106122160190227259292
E,83052800833346
Fialová893528008332477995133165198
D.110852800834556
Doporučené118252800834584123162184222254287326360
nástroje15605280083376996119141178193228
pro18055280083396098
revizi19205280083215587103132147
medikace208452800835893132148178211243277
a2378528008332
optimalizaci24275280083377799114172204220235264297329344
preskripce27895280083386094425538008326567894133166200
u640538008337
geriatrických6925380083387395110142164185201233263297328366
pacientů.107453800833871104119153191213251263
Geri135253800834479101116
Gero148453800834379100137
2023;163653800833569102136148
12(3):114-12617995380083346482115132144174202233256287316350
12.4255480085366884
Filipovský524548008332476277117155187214244278
J.81754800832537
Arteriální8695480083416387121142158190205243258
hypertenze114254800833869109144165190224262291325
ve148354800833165
stáří.15645480083264982103118131
Geri171154800834379100116
a1842548008332
Gero188954800834479100138
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13.4255580085366984
Agarwal53055800834180113134188222237
R,78855800833650
Sinha8595580083334886124157
AD,10375580083418899
Cramer11575580083406195153189210
AE,13885580083417588
et149755800833457
al.15755580083324861
Chlorthalidone16575580083407894132154179218251266282321360399434
for21125580083185778
Hypertension221155800834577117153175200234273300315353392
in262455800831553
Advanced26985580083418011314618542556800833165104
Chronic5485680083407799136174189221
Kidney7875680083355291129164195
Disease.10005680083466187122154181216228
N1246568008345
Engl130956800833370109125
J1452568008324
Med.149456800835590129142
2021165556800833468101132
Dec180556800834681114
30;385(27):2507-2519.19375680083346981116151185202236269289301336371405438456487522553583594
doi:25495680083387792104
10.1056/26715680083356679109141175209234
NEJMoa2110730.42557800834578105159198231265297324356388423457470
14.4255880085366984
Widimský52558800835774112128185212242275
J,81658800832436
Filipovský868588008332476277116155187214244278
J,116158800832537
Ceral12135880083407495128143
J,137258800832436
et142458800833456
al.14955880083324861
Diagnostické15715880083456193132170208235258273305335370
a1956588008332
léčebné20035880083155083116155194229
postupy224758800833978105128166205236
u2499588008337
arteriální25515880083325378112133149181196234249
hypertenze.2815588008338694255980083387495119153191220253265
Doporučení70359800834584123162183221253286324339
České10555980083397399129163
společnosti123159800832664103119153186223261288311326
pro15705980083386097
hypertenzi.167959800833868108143164189222260289304317
Hypertenze200959800834476115151172196229267296330
a2352598008332
KV239659800833574
prevence24835980083386093125159197229263
2022;275859800833468101135148
2:42560800833447
1-25.4846080083355384119131
dostupné62860800833876102125163202241275
z:91660800832942
https://www.hypertension.cz/wp-content/uploads/2023/01/Widimsky_-guidelines-CSH-2022.pdf.9716080083385983123149162188209260313366377416446486521543567601639665680718756769801831859910950973100710441082110311371175119612241260129913151353138614251451147615111545157816131637167117021724178418011839185419124256180083265690124146186224239278313328343381416443464507541585607638672705740752792832851863
15.4256280085366883
Beckett52462800833571103133167190214
NS,7546280083457790
Peters8606280083356891124146173
R,104962800833549
Fletcher11146280083324782104135173208229
AE,13596280083417487
et146262800833456
al.15346280083324861
HYVET161062800834581120154189
Study18156280083335492131163
Group.199462800834365102140180192
Treatment22026280083335084116137196231269290
of250862800833757
hypertension25816280083376810814316518922326128730242563800833776
in51863800831452
patients5876380083397294109144182203231
8083563800833470
years9226380083306597118145
of108463800833757
age115863800833271105
or128163800833758
older.13566380083385493127149159
N1532638008345
Engl159463800833270109125
J1736638008324
Med.177763800835489129142
2008;358(18):1887-98.193663800833468105140152187220254273305336354366396427462495514549584597
doi:25506380083387692104
10.1056/26716380083346678109140175209234
NEJMoa0801369.42564800834578105159198231266302337369399433467478
16.4256580085366985
Warwick52365800835789110163179211241
J,77765800832436
Falaschetti8276580083326177109135168206241263287303
E,114365800833246
Rockwood120265800833573106136189227266305
K,152165800833549
et158365800833457
al.16536580083324760
No172665800834583
evidence18226580083346782121156194226260
that20956580083226092114
frailty2222658008319417489104127160
modifies239665800835795135150168185219246
the26556580083226095
positive2764658008338771041194256680083223769104
impact54466800831573112145177201
of76166800833756
antihypertensive8336680083327092107145175215251272297331369395410442477
treatment13256680083224377109131189224262284
in162566800831452
very16936680083316687121
elderly18306680083344988123144160192
people:203866800833874112152168203215
an226966800833270
investigation23556680083145283118144168183222254276291329368
of273866800833757
the28116680083215994
impact42567800831572111144177201
of64367800833756
frailty716678008318417489104126160
upon89367800833776115153
treatment10636780083224377109131189224262284
effect13646780083345372107139163
in154467800831553
the16146780083216095
HYpertension172567800834480117153174199232270297312350388
in213067800831552
the21996780083226095
Very23116780083366890124
Elderly24526780083324786121142158190
Trial2659678008332496597112
(HYVET)2788678008319639942568800833670105127
study,5676880083264987126158168
a750688008332
double-blind,79868800833876114153169204227267283298336375387
placeb.12016880083385486119152192204
BMC142068800833691131
Med.156768800835489129142
2015;13(1).172468800833468100130141171201219251265276
doi:10.1186/S12916-015-0328-120166880083387691103133165177208236267302327360391421455487518541579610640662700733765799822853
17.4256980085366876
Williamson5166980083577489104119151209235273312
JD,8436980083247081
Supiano93969800833269109124156194232
MA,118669800835597111
Applegate131269800834180120135170210242264298
WB,162569800835793106
Berlowitz17466980083357192108146197212235266
DR,20266980083468296
Campbell213769800834073130170209245260275
RC,24276980083367689
Chertow253169800834078113134159196247
GM,279369800834498112
et42570800833457
al.5037080083324862
Intensive5867080083155375110149175191224259
vs86670800833259
standard9467080083275184123163196217256
blood12237080083395694134174
pressure14187080083396296124151189210245
control168470800833269109131153191207
and191270800833271111
cardiovascular20447080083316587125141180212246273306344360393415
disease24807080083385481116149176212
outcomes2713708008337769913116842571800835792119
in56071800831452
adults62871800833170108123146173
aged81771800833271106145
≥7597871800834174106
years:11007180083316597118145158
a1273718008332
randomized13207180083215492131169227243272306345
clinical1681718008331466199114146179194
trial.1891718008321435991106119
JAMA202571800832464120162
2016;220271800833469100131144
315:2673–2682.23617180083346595106141175208242278310344379413425
doi:28017180083397792104
10.1001/jama.2016.7050.4257280083346678109140177208230246278336369382418452484515528562595630664676
18.4257380085366985
Streit5317380083325475109124147
S,69873800833245
Poortvliet76473800833571110132156191207222256279
RKE,106373800833571105119
Gussekloo120273800834482108135170200216255293
J.151673800832436
Lower157273800833269120155176
blood17687380083395593132171
pressure19597380083396195122148185207241
during22207380083387697112150189
antihypertensive24307380083316991106144175215250272296330368394409442476
treatment4257480083224377109131189224262284
is72674800831541
associated7847480083325885123156171203225259298
with11007480083506688126
higher12447480083375291129164185
all-cause1447748008332476284118151188215250
mortality171474800835796117142175190205228261
and199374800833270109
accelerated21197480083326495129144179200233255289328
cognitive246574800833168107145160183198231265
decline27477480083397310612113642575800833873
in51575800831552
the5857580083216095
oldest-old.6977580083375392127154177197236252291304
Data10197580083457799132
from11687580083184078136
the13217580083226095
Leiden14337580083326681120155193
85-plus16437580083346891131146184210
Study.18717580083325391130162172
Age206075800834180115
Ageing219275800834179114129167206
2018;241675800833468100131143
47:545–550.25767580083346676112147180216250282317329
doi:4257680083387692104
10.1093/ageing/afy072.5447680083346678109141176208233263302337352390429455486505539575608642654
19.30472280085366982
Douros315022800834584122144181208
A,337822800834156
Tölle34542280083337086101136
M,361022800835569
Ebert369922800833372108129154
N,387322800834558
et395122800833457
al.40282280083324861
Control410922800834077116137159196212
of434222800833757
blood44192280083395593132172
pressure46112280083396195122148186207241
and487322800833170109
risk5002228008321376393
of511522800833857
mortality519322800835796117142175190205228262
in547522800831553
a3047238008332
cohort309923800833168107145167191
of331123800833756
older33872380083385492127149
adults:355623800833271108124146174186
the37622380083226095
Berlin38782380083357091107122160
Initiative4058238008315536891106138160175207242
Study.43202380083325391131162172
Eur45132380083326990
Heart462323800834479111133157
J4800238008325
2019;484523800833468100130143
40:2021–2028.50082380083347083119153186217250281315348382396
doi:54242380083387692104
10.1093/eurheartj/ehz071.30472480083346678109140176208233264302323362397428450474490516548586615651684716726
20.30472580085367287
Rea314725800833570102
F,326225800833238
Cantarutti331325800833972110131164185223246270285
A,361125800834155
Merlino367925800835489110126141178217
L,390825800833245
et396625800833456
al.40352580083324760
Antihypertensive410825800834179100115153184223259280304338376402417449483
treatment46042580083224377109131188223261283
in490025800831452
elderly49652580083344988123144160191
frail5169258008318407388103
patients:52852580083397293108143181202230242
evidence30472680083346682121156194226260
from33242680083194178136
a3478268008332
large35282680083154768106141
Italian3687268008315377085100132170
database.38752680083387092125164197223258271
Hypertension416326800834476116152173198231269296311349387
2020;456826800833468101135148
76:442–449.47342680083346678113150182216253290323334
doi:50862680083387692104
10.1161/HYPERTENSIONAHA.120.14683.52082680083346578109136167198220265301304727800833567103137171216248263311356397442483498529559593605636667703739773785
21.30472880085367082
Sheppard314728800833270105145184217238276
JP,34412880083256065
Lown352428800833169120158
M,370028800835568
Burt37862880083367495119
J,392428800832436
et397828800833456
al.40522880083324760
Generalizability413028800834479117152174207222237266300339354370385407441
of458928800833756
Blood46632880083365190128168
Pressure48492880083355690117143180202236
Lowering510328800833168119154175191229268
Trials5389288008332496597112138
to304729800832259
Older312129800834763102137158
Patients:32942980083366889105139177199227239
Cross-Sectional35482980083406199125152173204239272296311349388420436
Analysis.399929800834179111127159186200226240
J4254298008325
Am429429800834199
Geriatr440829800834480101116148170192
Soc461529800833271103
2020;68:2508-15.473429800833468101135148184219231267301336371394425455467
https://doi.52162980083375983123149162189209245283299312
org/10.1111/jgs.16749.30473080083375997123156188200231259286314336352391417431461492525556589600
22.30473180085367390
Todd315331800833367108147
OM,3317318008347103117
Wilkinson34503180083577490121138176204242282
C,374831800834054
Hale38183180083447793129
M,396331800835569
Wong404831800835895134174
NL,42383180083457892
Hall43463180083447894109
M,447231800835468
Sheppard455731800833271107147187221242281
JP,48553180083246066
et493731800833457
al.50103180083324862
Is508831800831542
the51463180083226197
association52593180083325986125159175207230246304732800833776
between31433280083387598151187223261
blood34243280083385594133174
pressure36173280083396196123150188210245
and388132800833271111
mortality401132800835796119144177194209232267
in429732800831553
older43703280083375493129151
adults454032800833272110126149177
different4737328008338547493128150185224246
with50023280083516790129
frailty?5151328008318417490106129164188
A5358328008341
systematic54193280083265987304733800832256115148170186219
review32813380083215689105140192
and348833800833271111
meta-analysis.361433800835793116150173206244277294326354369396410
Age404033800834180115
Ageing417033800834180116132170210
2019;48:627-35.439533800833569102133146182218231267302335354388421434
https://doi.org/10.1093/48443380083386085125152166193214251290306319358381419446480512525557589625658683
ageing/afz072.304734800833272107123162201228259279310347381416429
23.30473580085367287
Benetos314935800833571109144166203230
A,339335800834155
Petrovic34633580083356890112149181197229
M,370635800835568
Strandberg37893580083325375108146185224260281319
T.412235800833342
Hypertension417935800834476116151172197231269295310348386
management458035800835790128160199234292327365386
in498135800831552
older50483580083375392127148
and521135800833169108
frail5334358008318407389104
older54523580083385330473680083387394
patients.31573680083387193108143181203230244
Circ34163680083405576107
Res35393680083357097
2019;365136800833469100131143
124:1045–1060.38103680083346496108137169205238274305337372408420
doi:42463680083387691104
10.1161/CIRCRESAHA.118.313236.43653680083346578109136168198220259274310350386420453494539580595626653684698733764794827861896909
24.30473780085367186
Dave314837800834578109143
CV,33063780083407887
Li340737800833147
Y,346837800833544
Steinman35263780083325487102140198230269
MA,380937800835496110
et393437800833456
al.40043780083324760
Antihypertensive407937800834179100116154184224260281306339377404419451485
medication457937800835792132147179212233249287325
and491937800833169108
fracture50423780083184073105130167189223
risk5279378008321366292
in538637800831452
older54533780083375330473880083387394
veterans31543880083316587121142175212239
Health340538800834479111126148186
Administration360438800834179137152189204230253274307329344382420
Nursing403738800834482103130145182221
Home427138800834482140175
residents.4459388008320548195134169207228256269
JAMA474138800832464119161
Intern49143880083155374108129167
Med.509438800835489129142
Published524838800833572111127142168205240280
online30473980083377691106144179
April324139800834180102118133
22,33893980083346982
2024.348639800833468101133145
doi:10.1001/jamainternmed.2024.0507.36473980083387691104133165177208240276308329346378435468483521542576597636694729768781818852884916929964998103210651071
25.30474080085367387
Sheppard315540800833371106145185218239278
JP,34534080083246065
Koshiaris35394080083347299137152184206221247
C,380740800834053
Stevens38814080083325487120154193219
R,412140800833549
et419140800833456
al.42684080083324760
The434940800833272107
association44764080083325986124157172204226242280318
between48154080083397497150185220259
antihypertensive50944080083327092107145176216252273298332370397412304741800833266
treatment31334180083224478110131190225263284
and343841800833270109
serious3567418008326618398136175201
adverse378841800833271104138160187222
events403041800833467101139161188
by423941800833970
age432941800833271106
and445541800833270110
frailty:4585418008318407489104126160174
A4779418008341
cohort484041800833269107146167192
study.50524180083265088127159169
PLoS524141800833567104136
Med539741800835590130
2023;20:e1004223.304742800833468101136147182216229264294325361397430465500512
https://doi.org/10.1371/journal.pmed.100422.357442800833859841231501621892102452842993123503724104364695005135445746066386606767147527748128448608739139711006104610591089112111571193122612611273
26.30474380085367187
Sheppard315543800833270105145184217238276
JP,34524380083246064
Benetos353743800833570108143166203229
A,378743800834155
Bogaerts386243800833674114146181202227254
J,413743800832436
et419343800833457
al.42704380083324760
Strategies43514380083325375108129163203218253279
for46514380083185677
Identifying47494380083145488127148163183217233271310
Patients50794380083356789104139177199226
for53264380083185677
Deprescribing54244380083458030474480083396094121153175190229245283322
of338444800833756
Blood34554480083365189128168
Pressure36384480083355690116143180201235
Medications388844800835590130145177210231247285323349
in425244800831553
Routine432044800833573112134149187222
Practice:45574480083355689121145161193226239
An481144800834179
Evidence49054480083326480119154192224258
Review.517844800833570102118153204215
Curr54084480083407697119
Hypertens304745800834476116151173197231269295
Rep335845800833570109
26,34834580083346780
225–236357845800833569104141172207241
(2024).38354580083185286119151168179
https://doi.org/10.1007/s11906-024-01293-5.4030458008337598312214916218820924528329831134937140943546850051254357561164366368871874577681184787190894197299510331064109411281161118312171229
27.30474680085367079
van313946800833164102
der32534680083387394
Wardt335946800835788109147169
V,354146800833544
Harrison35974680083447697119134160198236
JK,38454680083245974
Welsh393246800835789105130168
T,411246800833341
et416646800833456
al.42354680083314659
Withdrawal43074680083577295132171192225275307322
of464246800833756
antihypertensive47114680083316990105143173213248269293326364390405437471
medication:519446800835792131146178210232247284322334
a3047478008332
systematic30914780083265985108142199231253268300
review.34034780083215587102136187198
J3614478008324
Hypertens365047800834476115151172196229267293
2017;39564780083346899128138
35:1742–1749.41074780083346677107136166198232263292322355366
doi:44854780083387691103
10.1097/HJH.0000000000001405.46014780083346577108139174207226271296341354389424460496532568604640675711747783814845881915926
28.30474880085367288
Ekbom314848800833362103142200
T,336148800833341
Lindholm34154880083324785124162200216274
LH,37024880083317689
Odén380448800834786121159
A,397648800834155
et404448800833456
al.41134880083324860
A4186488008341
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