801
PŘEHLEDOVÉ42522001004388130181216258306358404446
ČLÁNKY88722001003973122176223272
Transplantace4253300100365591129157195211246284310347377411
ledviny8523300100155089126142179215
u1083330010037
pacientů113633001003773103118153191218257
s1409330010028
mnohočetným145333001005997136174213244278305343379440
myelomem:190933001005995130146184245280340355
současné228033001002968106137172201239274
možnosti257033001005998129167206235263279
52019422001003471117
|351220010018
VNITŘNÍ4268040010746106127172220280301
LÉKAŘSTVÍ748804001074185130188236280325378400
/11948040010731
Vnitř1270804001074693112140166
Lék.1456804001074083122140
2024;70(8):517-5211615804001074487129169183224266291333355370414453490513556598637
/22978040010732
www.casopisvnitrnilekarstvi.cz442680400107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
rozvoje425328001072672107150196215258
sekundárních698328001073377114161208257296322370388427474
malignit,11883280010772112130148196243261289304
které1508328001073767109135177
u17013280010747
nich1763328001074866105152
přestavují1931328001074975117150178218257305323341
nejčastější2288328001074791109148188221249291309340358
příčinu266232800107497593132150197243
úmrtí4253420010748121148179198
po642342001075099
transplantaci76134200107285496144177226246286335361403443462
ledviny1243342001071963113154173221260
(24).1522342001072467107129142
Mnoho5653560010770119167216264
pacientů850356001075091132151194242269317
zejména118835600107367998171216264305
vyššího1513356001074184118151170219268
věku1802356001074083121170
má19933560010773114
navíc2128356001074889129148188
další2337356001074990109141159
přidružená251735600107507796145171220257299348388
onemocnění425370001074896140213261302349393441459
(hypertenze,900370001072472110161205231262304352388431445
diabetes1361370001074968107157201229271304
mellitus,16823700010773117136154172200247280296
kardiovaskulární1994370001073880106154172220260301334371419438478504552571
onemocnění),2581370001074796139213261301425384001074892140159187201
která646384001073868111137179
zvyšují845384001073680123157204223242
riziko110738400107264582101139186
morbidity13133840010774122149200219268287315357
a16903840010741
mortality17513840010774122149180221240259287329
primárně210038400107507796170210237286330
nesouvisející2449384001074993127175223264284316361379398438457
s4253980010733
MM.4733980010769137153
Z6423980010747
tohoto704398001072873120167193238
důvodu958398001074893133179228274
by1247398001074987
pacienti1349398001074989128146188235260278
měli16433980010772115133150
být1808398001074987117
před1940398001074975116165
plánovanou2120398001074967107153200239279326373419
transplantací255539800107275393139171219238277323425412001072869110128
ledviny572412001071963113155174222260
pečlivě852412001074994135154172213256
vyšetřeni1127412001074184118162190217259308326
na1472412001074889
přítomnost158041200107507796124170244293341374403
komorbidit,2002412001073986160208235286305354373401417
které2438412001073869111138181
mohou26384120010773122171219267
mít425426001077390118
negativní558426001074891139179205223263311329
dopad902426001074895144185233
na1150426001074888
výsledek1253426001074082115133176225268305
transplantace157342600107285394141173221240279326352392432473
a20614260010741
mohou21174260010773120167215262
být2394426001074987118
i25274260010719
důvodem2561426001074894134181229272344
kontraindikace425440001073987136164191234253302352372410453495538
transplantace.99044000107285698147181231251293342369412453496512
Optimální15294400010761112141160235276296345364
nastavení1920440001074990124154196237281330349
imunosupresivní2296440001071994142191241275323374401445480498540590609
terapie42545400107287198140190210254
po7054540010751100
transplantaci83245400107285597146179229249290339366408449468
ledviny1326454001071964115156176224263
není1616454001074993142161
dosud1803454001075099133180230
jednoznačně2060454001071963114163212247297338379427472
definováno.2559454001074993118138186235276318425468001074999114
Klíčová56746800107456685126174215257
je852468001071964
multioborová9434680010775124143172192241292342370418459502
spolupráce1472468001073484135155203254282324366409
v19094680010741
rámci1977468001072770145186205
předtransplantační2210468001075078121173202229272321355405425467516544586627676696
i30473280010719
potransplantační3083328001075099127153195243276325345385433460502542590609
péče3709328001075095136178
s39053280010733
ohledem3956328001074896115159209253327
na4301328001074889
imunosupresivní4407328001071992140188236270317366393436470488529578597
management,50213280010774115163204253297371415463490506
monitoraci30473420010774122171189217264291333373392
aktivity3459342001074078109128169189217259
MM37383420010770140
a38983420010741
v39583420010741
případě401934200107497695145186236280
relapsu431834200107277089130179213260
volbu4597342001074189108157206
terapie482234200107287197139188208251
MM50933420010770140
(16).5253342001072463103125138
Závěr30473670013862123184242288
Publikovaná3187384001074592142161180217265305347395435
data3645384001074990117158
ukazují,3826384001074886128165214233251267
že4115384001073779
definovaná4217384001074993117137185233273315363404
skupina4644384001073371119169188236276
pacientů4943384001075091132151194243269317
s52833840010734
ESKD5340384001074184128187
a30473980010741
MM31143980010770140
může32793980010774121158201
z35063980010736
transplantace356839800107275496144177226246286334361403443486
ledviny4079398001071963113155174222260
dobře4365398001074997148174217
profitovat,4608398001074976124148167195242282324351367
a50013980010741
proto5068398001074976123151197
by5291398001075089
tito540639800107284674121
pacienti3047412001074990130148192239265284
neměli3347412001074891164208226244
být3607412001075088119
vylučováni3742412001074183103149189235275315363381
z41394120010736
transplantační419141200107285495142175223243283330356397437484502
léčby4710412001071862102151190
pouze4916412001074998145181224
na5156412001074888
základě5260412001073678115135175224267
anamnézy3047426001074087126198244287323365
MM.34274260010769137153
Podmínkou3596426001074489137209227273310356402
akceptace4014426001074077115156204230270310351
k43804260010737
transplantaci443342600107275393140171219238277324350390429446
je4895426001071961
dosažení4971426001074895128168204245292310
remise5296426001072668139157189231
onemocnění,3047440001074897142216264306354399447466481
„cancer3555440001072667109157198241267
free384944000107245295140
perioda“4015440001075095122142190240281307
dle4349440001074968112
cytogenetického4488440001074083114161211256304349377396436474518566615
rizika513044000107264683102140183
a53394400010741
absence54074400010741913047454001073478126166208
zásadních3272454001073678112153203250269309357
komorbidit.3645454001073885159208235285304353371399416
Pečlivé4077454001074587128147165206249
multioborové43434540010773121140168186234284333360407447490
předtransplantační4850454001074976119169197223265313346395414455503530571611659677
vyšetření3047468001074184118162190216259307326
je3392468001072063
klíčové347546800107385977117163204247
pro3742468001074976123
individualizované3885468001071967116135176195244292332351370406453494535583628
posouzení4532468001075099133181229266309357376
transplantability.492746800107285597145178227247287335362403453472491509537580592
PROHLÁŠENÍ48549800974387144199239292335376430452
AUTORŮ:954498009749101143200245299316
Prohlášení128649700984573119166187229263305352373
o1674497009845
původnosti:173549700984693134179227274320354383404423
Publikace217449800954082127144161195233269308
byla24984980095447997133
zpracována264749800953378102139176218254291334371
s3034498009529
využitím307949800953775119152169195212277
uvedené337249800954380119163203246286
literatury3674498009517335997121158183226249288
a3978498009536
nebyla403049800954383127163181217
publikována426349800954487132150166200243279316359396
ani46754980095367996
zaslána478749800953270100117153197233
k5036498009534
recenznímu50864980095236299137180213257274340382
řízení4855100095244174112156172
do67551000954387
jiného7795100095173477117160203
média.1000510009565105150167203218
Střet12355090098426998141170
zájmů:142150900983679100169215234
Žádný.167251000954380125168202214
Financování:190350900984161108149195232277318359406427446
Ne.236651000955191104
Poděkování:248750900984590137180221266307348395416435
Ne.293951000955191104
Registrace306150900984688135156190219248290326368
v3445509009841
databázích:350350900984687116158205247284306342389408
N/A.392751000955180122139
Projednání408350900984573119141183231278319365387
etickou44865090098417192128170214261
komisí:476350900984186155176210231250
N/A.503051000955180122139
LITERATURA426533001234978134189250318368438498567
1.42555000853648
https://www.hematology.cz/cervena-kniha-lecebne-postupy-v-hematologii/4895500083385983123150162189209260314367378417452510542564601617655694726736768799827856889911945980101810501072110311431158119612281250126713021334136814071446148115041544158316091633167117101741176317961818185718921949198220042040205620952134214921642190
2.42556000853651
Malúšková49056000835487102139139157157195233265282282
D,80056000834656
Svobodová86956000833363101140179218256288305305
I,120356000831527
Kuč1243560008335728989
erová13475600083345592124141141
M,151656000835568
et159756000833456
al.16665600083324760
Epidemiology17395600083327187125160218233271287325364396
of214856000833756
multiple221756000835795110132148187202237
myeloma246756000835788122138176234266
in274656000831552
the28115600083226095
Czech42557000834071105137175
Republic.61657000833570109147187202217249263
Klin.8945700083355166104118
Onkol.102757000834786116153169182
2017;30:35-42.122457000833468100130139174209222257290312349381394
3.42558000853651
Barlogie4955800083356889105143183198233
B,74758000833548
Mitchell8145800083557092123161196212227
A,106058000834155
van113458000833265103
Rhee125658000833574109144
F,141958000833238
et147658000833457
al.15525800083324760
Curing16315800083407698113151190
myeloma184058000835888123138176235267
at212658000833254
last:2199580008315477396110
defining23285800083387391107145160198237
criteria2584580008332536891125146162194
and279758000833169108
providing4255900083396097129145184199237276
the7165900083226095
evidence.8275900083346682120155193226259271
Blood11145900083355189128167
2014;124:3043-3051.129759000833468100131142173202234246282316352385407439474508539548
doi:18615900083387691103
10.1182/blood-2014-07-55205919805900083346578109136167201228268284322360400422453487519550573610643662696728761795829862
4.42560000853651
Há4906000083446161
jek5676000083155080
R,66060000833649
Maisnar72360000835487102128166198219
V,95660000833544
Krejčí10136000083355892107139139149149
M,118060000835568
et126160000833456
al.13316000083324760
Diagnostika14046000083456193132170208235258274304337
a1754600008332
léčba179960000831550507272122155
mnohoč196760000835795134172210227227
etné22096000083345795113113
ho234060000833776
myelomu.242960000835788122138176234272285
Transf.27276000083335083121147167179
Hematol.42561000834479137169191228244257
Dnes.69761000834584119146159
2018;(Supl.1):1-155.87261000833468100131143162194231270286299330344356386405435466498510
5.42562000853650
Rajkumar4926200083356883114152210242263
SV.7716200083326979
Multiple86662000835492107130145184200235
myeloma:111762000835788122138176234266279
2014141162000833569100131
Update155862000834483123155177210
on178462000833876
diagnosis,18766200083385385124162200227242268281
risk-stratification,2173620008321366292113140163184217239254272289321354376391429467480
and266962000833270109
management.27946200083578942563000833870109144202237275296310
Am.75063000834199112
J.87863000832436
Hematol.92963000834580138170192229244257
2014;89:998-1009.120263000833468100131143178212225260296331353384416452487498
doi:17156300083387692104
10.1002/ajh.23810.18346300083356679109141177210236267282320333369404439470502514
6.42564000853652
https://www.myeloma.cz/res/file/guidelines/2023-transfuze-hematologie-dnes.pdf49264000833859831231501621892092603143673784364675015175556136466596917227507698038308568748919069419671002104010551094112911451160119712321259128513201354138714221444146614871520155815851605164316731707173017691804186218941916195319692007204620622096211921602198223322602273231323532372
7.42565000853544
Rhee48165000833572106140
F,63365000833237
van,68265000833163100112
Szymonifka8066500083326093150187224239257289321
J,113965000832436
Anaissie118665000834178109123149174189222
E,142065000833245
et147665000833455
al.15436500083314658
Total16136500083326586118133
Therapy175865000833270104124156194224
31994650008334
for20406500083185475
multiple212765000835693108129144182197231
myeloma:237065000835686119134171228259271
prognostic265265000833859951341712082344256600083223769
implications50866000831472111127142174207229244282320347
of86966000833756
cumulative93966000833169127165180212234249282316
dosing126966000833876103118156195
and147866000833169108
premature16006600083396195153185207245266300
discontinuation19146600083385379111148187208224261299331353368406445
of237366000833756
VTD244366000833673120
maintenance25776600083578910514216419823626830642567000833165
components,50467000833168127166205243278316338365378
bortezomib,8976700083387799123157187224282297336348
thalidomide,12606700083216092107122161199257273311346358
and163367000833169108
dexamethasone,175667000833873104137195230252290323349387426461473
relevant22436700083215570105137170208230
to248767000832259
all25606700083324762
phases263767000833877109136171197
of284967000833756
therapy.4256800083226095116149188219229
Blood.2010;116:1220-1227.6706800083355189128167180216251282314327357384416428458488522557580611641676709715
doi:14006800083387792104
10.1182/blood-2010-01-264333.15196800083356679109137168202228268284322361401423454488520551575612644663694727764796829862875
8.42569000853652
Heher49569000834479117152174
EC,6876900083327385
Rennke79069000833671109147177211
HG,101969000834489102
Laubach113969000833265103142175207245
JP,14026900083246064
et148469000833457
al.15596900083314760
Kidney16376900083355190128163194
disease18496900083395480115147173208
and207569000833270109
multiple220269000835795110133148187203238
myeloma.245869000835788122138176234267280
Clin27566900083405570108
J2882690008324
Am42570000834199
Soc53970000833371104
Nephrol.65870000834580119158179216232245
2013;8:2007-2017.91870000833468100130141177189224258294327346376411442472478
doi:14117000083387792104
10.2215/CJN.12231212.15307000083356679115149181211235274301346359390420455489520550582612624
9.42571000853649
Kyle4897100083356480115
RA,6187100083357892
Gertz72471000834480101125156
MA,89471000835597111
Witzig10197100083577396127142181
TE,12147100083336780
et130871000833456
al.13787100083324760
Review145271000833671103119154205
of167171000833756
102717417100083356699132
patients18877100083397293109143181203231
with21327100083506688126
newly227271000833873124140172
diagnosed24587100083385385124162200227262302
multiple277471000835795110425720008322377692127
myeloma.56772000835788122138176234267280
Mayo86272000835587118156
Clin10337200083405570108
Proc.11567200083365693126139
2003;78:21-33.131172000833468104137149182215227262294313345378390
doi:17177200083387691104
10.4065/78.18367200083346678113148184218242278311324
1.217672000833443
21.22357200083346575
10.4257300085367288
Klomjit5377300083355393153170187211
N,77173000834560
Leung85473000833268107147188
N,106573000834560
Fervenza11487300083336991128164204235270
F,144173000833340
et150573000833458
al.15877300083314863
Rate16737300083367194129
and182673000833272112
predictors19627300083396298139156190215254277306
of229273000833758
finding23747300083183675116133173213
monoclonal2611730008357981381782122292694257400083387188
gammopathy53674000833872131190230271306329368400
of95974000833858
renal10417400083205695129146
significance12107400083264282122138159176210244283317352
(MGRS)158574000831974120157192213
lesions1821740008315517996135175202
on204774000833777
kidney21477400083304788127163196
biopsy23667400083395695136165199
in258874000831454
patients26657400083387396113149188211240
with4257500083516891131
monoclonal57975000835797137177211228267307341357
gammopathy.96075000833871131190230271305328368400411
J1394750008324
Am1442750008341100
Soc156575000833372106
Nephrol.169575000834481121161184222240254
2020;31:2400-2411.197275000833470104140154190223233269302340377403435468500529540
doi:25357500083387894108
10.1681/26667500083346781113146183216239
ASN.2020010054.42576000834176122137174210244280317350383421456493507
11.30475500085366678
Dykes314255000834578109143170
K,332855000833550
Desale339455000834581108141156191
S,360155000833346
Javaid36635500083245688121136175
B,385455000833648
Miatlovich391955000835469101123139177209225257295
K,423055000833549
Kessler42965500083356996122138172194
C.450655000834053
A4576550008340
New463355000834580131
Reality478055000833570102118133155189
for49855500083195678
Multiple507955000835592108130145185200235
Myeloma533155000835486120136174304756000835790
Renal315256000833570109141156
Failure:3324560008332617792129150184197
US353656000834476
Data362756000834678100132
Report377556000833570109148170194
on398556000833776
Kidney40765600083355190128163195
Transplant42865600083335083121147186202234272294
Outcomes.459556000834786108139176234269296310
Clin49205600083405570108
Lymphoma504356000833260119158196235293325
Myeloma538456000835486120304757000831553111144
Leuk.320657000833165103133148
2022336957000833468101136
May;22(5):e314-e320.352057000835587118131166201219252270282317351382413436473507540574586
doi:41225700083387691103
10.1016/j.clml.2021.42415700083346578109140172203228244257289305362378391427461493525534
11.47915700083346171
002.487757000833470103116
12.30475800085366884
Bridoux31455800083355772111149187219
F,337858000833238
Carron34305800083407294115153191
PL,36355800083356680
Pegourie372958000833568108146184205221255
B,399858000833648
et406058000833456
al.41305800083324760
for42045800083185678
the42965800083215994
MYRE440458000835590126160
Study45785800083325491131162
Group.475458000834466103141180193
Effect49605800083335271105138162
of513658000833756
high-cutoff52065800083385392130152186224246283303322
hemodialysis304759000833873130169208223255271303330344371
vs.34345900083325972
conventional352359000833168107138172210232247285324356371
hemodialysis391159000833772130169208223255271302329344370
on429859000833776
hemodialysis439059000833873131169209224256271303330345371
independence47775900083155392127166202240279314352384418
among521159000833290128167206
patients54335900083397230476000083223772110131159
with32216000083516689127
myeloma336360000835788122138176234267
cast36456000083316490114
nephropathy:377460000833772111150171208248281303341371385
a4174600008332
randomized42216000083215492131169227242271305345
clinical4581600008331476299115146179195
trial.4791600008321435991106119
JAMA492560000832464120162
2017;318:510260000833468100129139174205236248
20992110.53656000083346810413930476100083346693125137
doi:32006100083387691103
10.1001/jama.2017.17924.33196100083346578109140176208230246278336368382418452483513519550579613646678690
13.30476200085366883
Hutchison314762000834482104135173188214253291
CA,34556200083398296
Cockwell356862000834077109139193227243258
P,384262000833540
Moroz389962000835492114151179
V,409562000833644
et415662000833456
al.42296200083314760
High43056200083445998136
cut44586200083316991
off45666200083375776
versus46586200083326688115152178
high-flux48536200083375291129152170187224255
haemodialysis512562000833870105163201241256288303335362377403
for30476300083185678
myeloma314263000835788122137176234266
cast34256300083316491114
nephropathy355663000833772112150171209248281303341372
in394563000831452
patients40146300083397293109143182203231
receiving42626300083205487121136168184222261
bortezomib-45406300083397899124158187224283298337360
based49176300083397298133173
chemotherapy510763000833169104162200222260295317350389420
(EuLITE):30476400083195188120135169203223235
a3298640008332
phase334664000833978110136171
23534640008334
randomised35846400083215492131169227242269304343
controlled394364000833268107128150187203218253292
trial.4252640008321435890106119
Lancet438764000833165103135169191
Haematol.459464000834477112169202224260276289
2019;6:490064000833468100130143178191
e217-e228.510764000833468100129148184219253287300
doi:54246400083387691104
10.1016/S2352-3026(19)30014-6.30476500083346678109140172203228261295330363396416448483516549568600630648681716752784815838875888
14.30476600085366984
Au315066000834178
EH,32476600083327789
Chapman335566000834078110149208240278
JR,36526600083246074
Craig37456600083406194109148
JC,39116600083246578
et400866000833456
al.40836600083324760
Overall416266000834780115136169184199
and438066000833270109
Site-Specific45086600083324769103126158196232265280297314347
Cancer487366000834073111143177198
Mortality509066000835493114139172187202225258
in536766000831553
Patients54386600083356730476700083223874113135163
on323267000833877
Dialysis33306700083466395111144172187214
and356567000833372112
after36986700083325278112134
Kidney38546700083355292131167199
Transplant.40756700083335184124151191207240279301315
J4412670008324
Am4457670008342101
Soc458067000833372106
Nephrol.470767000834581122161183221238251
2019;30(3):471-480.497967000833570103134147183219239273291304339372405424462499535548
doi:30476800083387692104
10.1681/ASN.2018090906.31666800083346678109140176208229267301345358394428460491527562598633668704718
15.30476900085366883
Decourt314469000834581113150188210234
A,339369000834055
Gondouin346269000834482121160198236251289
B,376669000833548
Delaroziere38286900083458196128150187215231265287321
JC,41636900083246578
et425569000833457
al.43266900083324760
Trends44006900083335084122161188
in460269000831552
Survival46696900083327091126141174207222
and490569000833270109
Renal502969000833570108140156
Recovery519969000833671103140172206228262
in547569000831552
Patients30477000083356788104138176197225
with32857000083506688126
Multiple342470000835492107129145184199234
Myeloma367170000835486120135173231263
or394770000833759
Light-Chain40197000083314685123144164206244276291329
Amyloidosis436170000834199129145183198237275302316342
on471670000833776
Chronic48047000083407899136174189221
Dialysis.50387000083456192108139166181207220
Clin52717000083405570108
J5392700008324
Am542870000834199
Soc304771000833271103
Nephrol.316671000834480119157178216232244
2016342671000833468100131
Mar357271000835587108
7;11(3):431-441.36967100083344474101117150167179214246277296332369400409
doi:41207100083397792104
10.2215/CJN.06290615.42407100083346578114149180210234273300345358394429463497533568599629641
16.30477200085356781
Huskey313972000834379104132165194
JL,33447200083245466
Heilman34217200083437690104159190226
RL,36587200083346577
Khamash374672000833472102158189213249
H,400672000834355
et407172000833454
al.41367200083314557
Kidney42037200083344986123156186
transplant43997200083214173109134171185216252272
in468172000831551
the47427200083225891
era48447200083335384
of493972000833654
modern500372000835793131164184221
therapy52347200083215891111142179209
for54537200083185474
multiple304773000835793108129144182196230
myeloma.328873000835787120135172229260273
Transplantation.35727300083324880117143180195226263284316336351388425437
2018;102:1994-2001.40207300083346798128139168199230242271300334369391421454489519528
doi:45597300083387589101
10.1097/TP.0000000000002449.46717300083346476106136170202221256292296330365400435471506541576611646681716748778814846856
17.30477400085366876
Chitty31397400083407893115140173
DW,3328740008345103113
Hartley-Brown34567400083447798123138173204226264285322373412
MA,388474000835496110
Abate401074000834180113135169
M,419474000835568
et427874000833456
al.43507400083324760
Kidney44267400083355190128163195
transplantation46367400083224376114141180196228266287320342357395434
in508574000831553
patients51547400083387193108143181203230
with54007400083516689127
multiple304775000835795110133148187203238
myeloma:330575000835888123138176235267279
narrative36057500083377091113146167183215249
analysis387575000833270102117149176191217
and411375000833169108
review42427500083205587103137189
of445175000833756
the45287500083216095
last4643750008315477497
two476075000832275113
decades.489375000833873106139178213240253
Nephrol516775000834479118157178215231
Dial54197500083456193108
Transplant.30477600083335083121147186202234272294307
2022336976000833569101136
Aug352176000834178117
22;37(9):1616-1626.36537600083346981116148165197215227257288318349373404435468502515
doi:41837600083397792104
10.1093/ndt/gfaa361.43037600083346578109140175208232269308330358394413446479513548578587
Diagnóza6212160471214580107164230295361410469
MM6211666471214597192
Renální1093117001074590138179197245264
selhání137611700107347897145186234252
v16481170010741
souvislosti1709117001073382130171190223242290323352371
s21001170010734
MM21531170010770140
ANO17711330010753110171
ANO17711640010753110171
ANO17712200010753110171
NE2459111001075799
NE2329160001075799
Pokračování2724117001074592130158200240287327368416435
ve3179117001074084
standardní3282117001073463104152202242269317365383
léčbě3685117001071963104154198
MM39031170010770140
Standardní2758180001074268109157207248274322370389
riziko316618000107274683102140187
MM33731800010770140
+35331800010753
ASCT3606180001075396147192
a29711920010741
MRD30321920010770115174
negativita3226192001074892142183210229270289317359
Referovat4320180001074590113157183230271312339
k46791800010738
transplantaci473718000107285496144177226246287335361403443462
ledviny4630192001071963113154174222260
Standardní2758226001074268109157207248274322370389
riziko316622600107274683102140187
MM33732260010770140
+35332260010753
ASCT3606226001075396147192
a27752380010741
MRD28362380010770115174
pozitivita3030238001074999134153181200241261289330
nebo3380238001074892142191
high-3591238001074866115163192
-risk281025000107275474106144
MM29742500010770140
a31332500010741
MRD31942500010770116174
negativita3388250001074892143183210229270290318359
Referovat4320232001074590113157183230271312339
k46792320010738
transplantaci473723200107285496144177226246287335361403443462
ledviny4630244001071963113154174222260
High-risk2737283001075775124172201228247280318
MM30742830010770140
a32342830010741
MRD32952830010770115174
pozitivita3489283001075099134153181200241261289330
Transplantace4283277001074263105153186235255295343370411452494
ledviny4797277001071963113154174222260
není5077277001074892140159
doporučena4538289001074997147196223272312355403443
Renální1162149001074590138179197245264
selhání144514900107347897145186234252
je1717149001071963
ireverzibilní180014900107194588129172198237256306325344391410
Konzultace1193180001074592141178226245273314355397
transplantologa.161018000107285596144177227246287335362408428476526567583
Pacient1105192001074585126145188236263
je1388192001071963
kandidátem1471192001073880128178196245286313356429
transplantace1920192001072855961441772272462873351478204001072869110152
ledviny1650204001071963113154174222260
Monitorace10582350010770119167186214260287329370412
odpovědi1490235001074898147196237280330348
na1858235001074889
léčbu1967235001071963104153201
MM21882350010770140
Obr.425600011362113150172
1.62160001135478
Doporučený726610010756102147193219264301338384419
algoritmus115861001074664109154180198223294339368
postupu154061001074590120146191237282
u1836610010745
pacientů189561001074590127145183229254299
s2207610010731
mnohočetným2252610010771117162208253291327353399434505
myelomem2771610010771106144162207278316387
a3172610010745
nezvratným323061001074684121161187229255301336407
selháním36506100107316987133177224241312
ledvin.397661001071856101139157203219
Optimálním4209610010757104129147217262281326344415
kandidátem463861001073680126171190235279305341412
transplantace50646100107265194140169213232276322347390427464
ledviny42572001071957102140159205240
je68772001071756
pacient,76472001074591129147185231256272
jehož105772001071857103148182
léčba12617200107185794138184
MM1466720010768136
zahrnuje162372001073680126152198243261299
transplantaci19447200107265194140170214233278324349393430448
kostní241472001073681111137183201
dřeně.263772001074570107153191207
Pacienti286572001074386123141179226251269
bez315572001074584121
dosažené329772001074691121166201238284323
remise364172001072663134152181219
by388172001074682
neměli398472001074685156194212230
být423672001074581110
k4367720010737
transplantaci44257200107275295141171215234279325350393431449
ledviny489572001071957103141159205240
indikováni,515772001071864110128165209247290337355370
neboť42583001074685130176202
rizika643830010726447997134178
vyplývající83783001073878123142179219263281300337355
z1208830010736
transplantace12608300107265294141170214233278324350393430467
převyšují174383001074571108146186216261279297
její2056830010718577493
benefit;216583001074584130169192211237253
převzato243483001074571108146183227253297
z2747830010735
(16)27988300107246198119