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a3511900010740
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terapeutické41759000107276792131178220265291307345380421
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původnosti:173511900984693134179227274320354383404423
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byla24981200095447997133
zpracována264712000953378102139176218254291334371
s3034120009529
využitím307912000953775119152169195212277
uvedené337212000954380119163203246286
literatury3674120009517335997121158183226249288
a3978120009536
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Střet12351310098426998141170
zájmů:142113100983679100169215234
Žádný.167213200954380125168202214
Financování:190313100984161108149195232277318359406427446
Ne.236613200955191104
Poděkování:248713100984590137180221266307348395416435
Ne.293913200955191104
Registrace306113100984688135156190219248290326368
v3445131009841
databázích:350313100984687116158205247284306342389408
N/A.392713200955180122139
Projednání408313100984573119141183231278319365387
etickou44861310098417192128170214261
komisí:476313100984186155176210231250
N/A.503013200955180122139
LITERATURA426155001234978134189250318368438498567
1.42517200853648
Visseren4871720083365278105140161195233
FLJ,7331720083336491103
Mach84917200835587119157
F,102017200833238
Smulders107117200833390128143182217238265
YM,135017200833590103
et146617200833456
al.15361720083314760
2021160917200833468101133
ESC175517200833266107
Guidelines18751720083448297136171186201239274301
on218917200833776
cardiovascular22781720083316485124139177209242268300338353386407
disease26981720083385379114146173208
prevention4251820083396094127161199220236274312
in75318200831452
clinical8201820083324762100115147180195
practice.10301820083396194126150165197231243
Eur12881820083336991
Heart139418200834479111132157
J.156618200832437
2021;42(34):3227-3337.161818200833468101133141176208225259294312324359392426459478510543576608614
2.42519200853651
Rinninella4941920083365087124138175208223237268
E,78019200833345
Raoul84219200833668105142156
P,101619200833539
Cintoni10731920083405491111147185198
M,128919200835567
et137419200833556
al.14481920083324658
What152319200835896127148
Is168919200831540
the17471920083215993
Healthy185719200834579110124145182212
Gut208719200834481102
Microbiota220719200835569100120156195209246267299
Composition?252419200834076133171209235249270284321358382
A425202008340
Changing47520200833975105141178191227264
Ecosystem7482020083336297121152177198230285
across10432020083316180116140165
Age,121720200834177110120
Environment,13462020083336897111130166202257290326346357
Diet,17132020083445891111122
and184520200833167104
Diseases.19582020083455983116146170203228240
Microorganisms22072020083546797117152188208244274310323347403427
2019,26432020083346696124133
7,278520200833438
14.28322020083346374
3.42521200853651
Sonnenburg49021200833271109147182220259298319357
JL,8612120083245670
Bä9452120083355353
ckhed,101421200833262101136175188
F.121621200833339
Diet-microbiota12692120083466196118138196212243265302342357395417450
interactions17332120083155274108129162194218234272310336
as208321200833259
moderators215621200835796135170191224246283305332
of250221200833756
human257321200833775133165203
metabolism.2790212008357924252220083225494132148163189247260
Nature.7012220083447798136158192204
2016;535:56-6492022200833468100131144179212245256291325349386422
4.42523200853651
Olvera-Rosales4892320083476395129151184206243281308341356391418
LB,9192320083326880
Cruz-Guerrero10122320083406199128150196234269290312346367404
AE,14292320083417487
Ramírez-Moreno152923200833568126141162196225247303341362396434473
E,201423200833346
et207323200833456
al.21422320083324760
Impact221523200831472111144176200
of242823200833756
the24972320083226095
Gut260523200834381104
Microbiota2722232008354701011231604252420083395492114146
Balance5842420083356884116153185219
on81624200833775
the9042420083226095
Health-Disease101124200834479111126149187209256271297332364390425
Relationship:14492420083357086118139155192231257295310348361
The182324200833271106
Importance194224200831572111150171196229266298332
of228724200833756
Consuming235624200834077115141178236251289328
Probiotics26962420083355693132148186425252008322376997
and53725200833270109
Prebiotics.6612520083355690129145183205220252280293
Foods.96925200833370109148175188
2021;10(6):1261.117325200833468101132140171202222255273285315344378408418
5.42526200853650
Bä4882620083355252
ckhed55726200833161100134174
F,74426200833238
Fraser7942620083335285111146167
CM,97426200834094108
Ringel10952620083355088126161177
Y,128426200833544
et134026200833456
al.14092620083324760
Defining14822620083458097114152167204243
a1738262008331
healthy178226200833872104119141179210
human200426200833875133165202
gut22192620083387698
microbiome:233026200835772104125162201216254312347359
current27022620083316989111145183204
concepts,42527200833168107139172212234261274
future7152720083185779117138173
directions,9032720083385374108141165180218257283296
and121527200833169108
clinical1339272008331466199114146179194
applications.154927200833171110126141173206228243281319346359
Cell19242720083407389104
Host204327200834483109133
Microbe.219127200835470102123160200235248
2012;12:611-22.245427200833468100130142172202215250280308327358393405
6.42528200853753
Jonsson50028200832565105132160200240
A,76128200834358
Bäckhed84028200833771105136177213254
F.111628200833340
Role11782820083367693129
of132928200833859
gut140928200833979102
microbiota153328200835975108131169210227266289324
in187828200831555
atherosclerosis.19542820083335696132154193221255271307329368396412439453
Nat242928200834680103
Rev255328200833773107
Cardiol.26812820083417698138154193210224
2017;14:79-87.42529200833468100129139169200212246279303339372378
7.42530200853645
Liu4873020083314784
Q,58930200834760
Li66730200833146
YC,7313020083357487
Song83530200833271109148
X,100130200833851
et107030200833456
al.11433020083324760
Both12213020083357496134
gut13723020083387698
microbiota148830200835772104125163202218256278311
and181630200833270109
cytokines19423020083316590127157174212247273
act22333020083326488
to233830200832259
atherosclerosis24143020083325492127148186212244260295316353380395421
in285230200831553
ApoE-/-42531200834180119153174199218
mice.65831200835773105138150
Microb82431200835470102123160200
Pathog.10393120083356789127165205218
2019;103827.127231200833468100130143173205238272306339345
8.42532200853652
Zhu49332200833876113
Q,62232200834760
Gao69832200834477115
R,82832200833650
Zhang89432200833775107145184
Y,109432200833544
et115332200833457
al.12253220083324760
Dysbiosis130132200834578105144160198224239265
signatures15823220083264180118150172210231265292
of189032200833756
gut19623220083387698
microbiota207632200835772104126163202218256278311
in240232200831553
coronary24713220083316889127165197219253
artery27393220083325378112133167
disease.4253320083385379114146173208220
Physiol66033200833573103130145183199
Genomics.87533200834379117155213228260288302
2018.119233200833468100131145
9.42534200853649
Yvan-Charvet49334200833567100138160203241273294329363386
L,89734200833145
Welch96034200835790106138176
C,115434200834053
Pagler122534200833567106121156177
TA,14213420083326983
et152234200833457
al.15973420083324760
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inflammatory1966342008315537087119177235267289326348382
gene236634200833873111146
expression253034200833465105127161187214229267305
in285334200831553
ABC42535200834177118
transporter-deficient5563520083224376114140179218240264298319339380414432449481496531569591
macrophages:116035200835790122143180220259291330365392404
free15783520083184074110
cholesterol170135200833169108123158185208242263301316
accumulation,20313520083326495133190228243276297313351389402
increased24463520083155385106140172199234273
signaling273335200832641791171504253620083153068107
via5483620083324880
toll-like644362008322597590112129143174208
receptors,8683620083215588121161183220241269282
and116636200833270109
neutrophil129236200833772110133154191231269284300
infiltration1608362008315537087102125146179201216254293
of191736200833857
atherosclerotic19913620083315391126147185211244259294315352374389421
lesions.2429362008315507791129168194208
Circulation.265336200834056771081451611932152304253720083377689
2008;118(18):1837-1847.52937200833468105140152182210241260292323341353382414447480498529560596628635
10.4253820085367085
Chacón52538200834078110142179218
MR,75838200835591105
Lozano-Bartolomé8783820083326997130169207230267300321346383399437495530
J,142438200832436
Portero-Otín14763820083357193118151173210233283307322360
M,185238200835467
et193538200833456
al.20073820083324760
The208238200833372107
gut22053820083387598
mycobiome231938200835788119156196211249307342
composition267738200833168126166204425392008326416379117155
is59539200831541
linked652392008314296797131171
to83839200832259
carotid9123920083316486123145160199
atherosclerosis.11263920083325492127148185212244260294316353380394420434
Benef157539200833671109144163
Microbes.175339200835570102124161200236263276
2018;9:185-98.204539200833468100131143178191221252286308343378392
11.4254020085366678
Kozarov51640200833572101134155192224
E.75340200833346
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invasion10684020083145284117143158196234
of131540200833857
vascular13854020083316491123161176208230
cell1628402008331658095
types:17364020083225696131158170
vascular19194020083326591124161177209230
infectology21624020083155372106139163200216254293325
and250040200833270109
atherogenesis.262240200833254921271481852252604254120083387399114140154
Future.5944120083336991129151185197
Cardiol.8064120083407394132147185201214
2012;8(1):123-138.103541200833569101130143178197229243255285315350371402432467480
12.4254220085366884
Liu5234220083314784
X,62142200833852
Xie6864220083395488
Z,78842200833851
Sun85342200833270108
M,97542200835468
Wang105642200835889127166
X,123642200833851
Li130142200833247
J,136242200832436
Cui14124220083407692
J,151742200832537
et156742200833457
al.16374220083324861
Plasma17114220083365082109167199
trimethylamine19244220083214359116151174212242258291348364401436
N-237442200834568
oxide24554220083386884122157
is262642200831541
associated268142200833258851231561712034254320083225595
with5374320083506689127
vulnerable6814320083317085123158179212251267302
plaque10004320083395587126163198
characteristics121543200833270102123156188212246267283309332347379407
in163943200831553
CAD170943200834082128
patients18544320083397293109143181203231
as210243200833158
assessed21774320083325885120147173208248
by244243200833970
optical25294320083377799114146179194
coherence2740432008331681071424254420083215593125159
tomography.59944200832259117155195216249288327357367
Int9824420083145274
J1071442008324
Cardiol.11114420083407294132147185201214
2018;265:18-134044200833468100131143178212246256286317340
23.16954420083346982
13.4254520085366883
Koren5224520083357294128166
O,70245200834758
Spor77345200833372110132
A,91845200834156
Felin987452008332668297135
J,113545200832537
et118545200833456
al.12554520083324760
Human132845200834582140172211
oral,15524520083375992107120
gut,16854520083387698112
and181045200833270109
plaque19324520083395587126164199
microbiota214445200835773105126163203218256278311
in246845200831553
patients25344520083397294109144182203231
with27794520083506688126
atherosclerosis.4254620083325492127148185212244259294316353379394420434
Proc8744620083355693126
Natl10154620083457799115
Acad114546200834172105144
Sci13054620083326480
U1400462008344
S1459462008332
A.150746200834155
2011;108157846200833468100127136166197233
Suppl182646200833370109149165
1(Suppl20064620083344981118157197213
1):4592-4598.2234462008334496195128160193214250283315350364
14.4254720085366984
Karlsson5234720083356890105131158196235
FH,7714720083337789
Fåk8744720083326293
F,98047200833338
Nookaew103247200834583122152186221272
I,131847200831427
et135947200833456
al.14294720083314760
Symptomatic150247200833363121160183220278310332347379
atherosclerosis18954720083325392127148185212244259294315353379394420
is232947200831441
associated23834720083325985123156171203225259298
with26954720083506688127
an283547200833270
altered4254820083324770103125159198
gut6384820083397699
metagenome.75248200835792115148187221260298356391403
Nat11714820083447798
Commun.128548200834077135193230268282
2012;3:1245.158248200833468100130142177189218248280313325
15.30471720085367086
Choroszy315317200834079119142180209240275
M,344817200835469
Litwinowicz35371720083324972127144183223275292326358
K,391517200833551
Bednarz398617200833572113152186208240
R,424617200833651
et431717200833458
al.43951720083324963
Human447817200834483142176216
Gut471417200834383107
Microbiota484117200835471105127166207224263286321
in518217200831454
Coronary525617200834078101140180213236271
Artery30471820083416389124147182
Disease:32451820083456289125158186222236
A3497182008340
Systematic35531820083326392116151210244267283317
Review388518200833572105122158210
and411118200833271111
Meta-Analysis.423818200835490114148172214254287304337365381408423
Metabolites.467718200835490114148188229246262286321349364
2022;12(12):1165.505618200833470104140153185216234267298318331362391423458471
16.30471920085367188
Kazemian315819200833570101136196212246285
N,346619200834459
Mahmoudi354719200835589128187227266307323
M,389319200835569
Halperin39851920083447895135172195212251
F.425819200833341
et432119200833458
al.44021920083314862
Gut448719200834483107
Microbiota461719200835471104127166207224263286320
and496019200833271112
Cardiovascular50941920083407597137153193226260288322361378411434
Disease:30472020083456290126159187224238
Opportunities330320200834788129169192218258297313337354390418
and373920200833272112
Challenges.386920200834079113130146183222262299327342
Microbiome422920200835571105127166207224263323360
2020,460720200833469104139153
8,477820200833448
36.48442020083357185
17.30472120085367081
Kriaa31522120083356077112146
A,332221200834157
Bourgin340321200833677117140181198238
M,366521200835570
Potiron,37592120083367599116139179219234
A,401721200834157
et409821200833559
al.41812120083324964
Microbial426921200835573107130170211229263280
Impact457321200831576117152186213
on481021200833778
Cholesterol491221200834081121139176205230266289329346
and528221200833373114
Bile54202120083365370107
Acid30472220083417490131
Metabolism:319622200835491114148189229247263291350363
Current357722200834078101124159199222
Status38172220083325589112151179
and401422200833272112
Future41442220083327094133156192
Prospects.43542220083355795124164201235260290305
J.467722200832438
Lipid47332220083314889105146
Res.489722200833572100115
2019;60:323-332.503022200833470103134149186223237274308344367401435469483
18.30472320085367188
Wexler315123200835792125142178201
A.G,336823200834157102117
Goodman350123200834384124165224258297
A.L.38142320083415791107
An393723200834180
Insider’s4033232008315548298139175197213240
Perspective:42892320083357092121161198232258274308344358
Bacteroides466323200833570103129164187225242282319347
as502623200833260
a5102232008331
Window514923200835875115155195247
into54122320083155477115
the30472420083226198
Microbiome.316324200835471104127166207224263323359373
Nat.355424200834478101116
Microbiol.368824200835572105128166207224264281295
2017;2:17026.400124200833470103134145181195227257292326361376
19.30472520085356983
Yoshida31452520083356996135151190223
N,338225200834458
Yamashita345525200833464122155182221236260293
T,376325200833241
Kishino38192520083355278117133171210
S,404325200833246
et410425200833356
al.41752520083314761
A4251252008340
Possible43062520083357299126142181198233
Beneficial455425200833570109144164181213229262278
Effect48472520083325174108142166
of502825200833757
Bacteroides510025200833468101125160181219235275310337
on545225200833776
Faecal30472620083326297130163179
Lipopolysaccharide32402620083314787126165204221253280314346377416448470486525560
Activity38152620083407296112145162185219
and404826200833170109
Cardiovascular41712620083397394133148187219252279312350366398420
Diseases.46052620083456187123155182217244259
Sci.4878262008332658094
Rep.498726200833470109122
2020;10:13009.512426200833368101135149179211225255285320356392403
20.30472720085367390
Yoshida31552720083357199138154195228
N,340127200834559
Emoto347827200833392131155193
T,368927200833343
Yamashita375027200833566125159187226242266301
T,406827200833343
et412927200833458
al.42052720083324863
Bacteroides428627200833569103128164186225242282318346
Vulgatus46502720083367491131165188227255
and492327200833271112
Bacteroides505327200833569103128164186225242282318346
Dorei54172720083468630472820083215673
Reduce313628200833572113152185220
Gut337228200834484108
Microbial349628200835471104127166207224257274
Lipopolysaccharide37862820083314889129170210228261289324357390429463485502542579
Production43812820083355796137176209235252291331
and472828200833271112
Inhibit48562820083155494110150167191
Atherosclerosis.506428200834063103139162200228262279315338376404421448463
Circulation30472920083405779112151167201224241280320
2018;138:2486-2498.338529200833470103136149181212248261298331369405430463496530567582
21.30473020085367184
Sasaki31473020083326694128160177
N,334030200834458
Takeuchi34143020083326293128167200239256
H,368530200834458
Kitano37593020083355276110149188
S,396330200833246
et402530200833457
al.40983020083314862
Dynamic417630200834579119152211227260
analysis445230200833271104121154182198225
of469330200833757
Porphyromonas47663020083357395136176208231269329368408441469
gingivalis52503020083385594134150184218234251278
invasion30473120083155386120147163202242
into33043120083155476114
blood34343120083385594134174
capillaries362431200833165105122138154187210226262290
during39293120083387799116155195
the41393120083226197
infection42513120083155474109143168184223263
process452931200833961100133168196224
in476831200831553
host483731200833776104128
tissues4981312008321386593131167195
using51913120083376480119159
a5366312008331
vascularized5413312008331659330473220083316985117139155185219259
three-dimensional33213220083215981115151175216231289324363390405443482515531
human386632200833775133166204
gingival40853220083375391130146179212228
model.432832200835695135170186200
Biomater45433220083345088147179202236258
Sci.4815322008332658194
2021;9(19):6574-6583.492432200833468101133142178198230260279292327361395426450487521556590603
22.30473320085367491
Grigorieva31583320083446784124163186204240273308
I.348633200831529
Atherosclerosis353633200834163103139162200229262279315338376405421448
and400533200833171111
trimethylamine-N-oxide41373320083214461120157180220252269303362379418454479527551592624640681717
—4874332008370
the49653320083216197
gut508333200833877101
microbiota520433200835774107130168209226266289323
potential.304734200833979102137177200216250267281
Russian334634200833575102130146180219
Journal358334200832564104126166200217
of381834200833758
Cardiology.38943420083407497136153192209249290323335
2022.424734200833470104140154
23.30473520085367490
Gaetti-jardim316035200834478114138164180204221255277317333392
E,357535200833247
Marcelino364435200835488111143178195212251291
SL,39573520083326580
Feitosa40593520083326884108147175209
AC,42903520083418296
et440835200833458
al.44883520083324963
Detection457335200834682106141175201218257297
of489235200833758
bacteria497235200833973107132167190207240
in523535200831454
atheromatous53113520083325594131153192304736200835791114153192220
plaques32873620083395690130169205234
of354136200833758
patients36193620083397396113149189212241
with38803620083516891131
coronary40313620083327093131171205228263
artery43143620083325581116138174
disease45083620083385582119152180216
by474536200833871
polymerase48363620083397997130190226249283311348
chain520436200833171104121160
reaction.5384362008321579012330473720083223878118132
Anaerobe.319737200834181115151173212253290304
2009;15(3):89-92.351937200833469107144158189221240275293307343379403440474488
24.30473820085367289
Hansen315538200834478117145181221
GM,3395382008344100115
Greve352938200834467102136171
JH,37203820083247084
Greve382338200834467102136172
ML.401438200835488103
Pseudomonas41363820083356399138179218278318358391419
aeruginosa45743820083326891131171188227267295329
microcolonies492238200835874108130169203241259298338354391419
in536038200831554
coronary54333820083316930473920083215999133155191
thrombi.32563920083226184122182223240254
Eur35283920083337193
J3639392008324
Clin36823920083395672112
Microbiol381239200835471104127166207224263280
Infect41113920083145474110144169
Dis.42993920083456289104
2016.442139200833570103136151
25.30474020085367490
Tungland315940200833367107147164198237277
B.345840200833550
Dysbiosis353040200834579108148165204232249276
of382840200833758
the39074020083226298
microbiota:402740200835773107129168209226265289323336
therapeutic43854020083226198120155195232271295312345
strategies47524020083265174108131166207224260288
utilizing5062402008337617794110141158197238
dietary53214020083385591115149171207
modification,304741200835797138155175193226260283300340379393
pro-346441200833861100125
and361241200833271111
prebiotics37474120083386197137154194217234267296
and406641200833272112
fecal42014120083185488123139
transplant43644120083214479118146186203237276299
therapies46864120083226298121155196213249277
in498641200831554
promoting506341200833962100160200223240279320
normal540641200833777100304742200835791108
balance31754220083397390123163196231
and342742200833171111
local35584220083155589123140
GI371842200834461
functions.37994220083185898131157173213253280295
In:41144220083155568
Elsevier;42024220083334977113147164200223238
2018:381-419.446042200833469103135149185221254274312344376388
doi:10.1016/B978-0-12814649-1.00009-0.48684220083387895108139172186218251285317344382417451486510549574606638304743200833467100137175210235267278314352389427463488527541
26.30474420085367390
Gao315844200834478117
M,329644200835569
Heng338644200834481120161
X,356744200833953
Jin36414420083244180
J,374244200832438
Chu380044200834079118
W.393944200835869
Gypenoside402944200834476117154194233261278318354
XLIX44044420083387188128
ameliorate455244200833291128145161201224258281316
high-fat48894420083385494134158179213237
diet-induced51464420083385591115136153193233272305341382
atherosclerosis30474520083315493129151189217250267302324363390406433
via34954520083324881
regulating35924520083205595134150183206222261301
intestinal39084520083155376111138162179218251267
microbiota,419045200835773106128167207224262285319333
alleviating45384520083324864100133150183205222261300
inflammatory4854452008314537392125183242275298336358393
response52624520083215683123163202229265
and304746200833271112
restraining31774620083205684109132166182222238277318
oxidative35134620083376986126160183200234269
stress38004620083275174109138166
in398446200831454
ApoE−/−405646200834181122157200226267
mice.434146200835774107142156
Pharmaceuticals.451546200833574108130190224257293332356372406440457484499
2022.503246200833470104140154
27.30474720085367283
Yan314847200833566105
N,327247200834559
Wang335047200835790129170
L,353947200833146
Li360447200833148
Y,367147200833544
et373447200833458
al.38114720083314862
Metformin389247200835591115137176199259276315
intervention42264720083145477112134170206246269285325364
ameliorates460947200833291128145161200223258281316344
AS497247200834176
in506747200831554
ApoE-/-514047200834181122157180205226
mice538547200835774107142
through30474820083226184122162202242
restoring33074820083205684109147170187226267
gut359248200833877101
dysbiosis371148200833872100140157197225241268
and399848200833171111
anti-inflammation.41274820083327295111135152191212231265324383417440457496536551
PLoS469648200833567106140
ONE.485448200834794128143
2021.501548200833470104137148