1304
PŘEHLEDOVÉ42522001004388130181216258306358404446
ČLÁNKY88722001003973122176223272
Význam42533001004380113151186246
s687330010028
metabolismem73133001005995122158196235251266295355390450
asociované119733001003463102133148187223258296331
steatózy15443300100295691126152191221258
jater18193300100144975110134
a1969330010034
její2019330010014506580
terapie21153300100256085120158173209
3623422001003477
|351220010018
VNITŘNÍ4268040010746106127172220280301
LÉKAŘSTVÍ748804001074185130188236280325378400
/11948040010731
Vnitř1270804001074693112140166
Lék.1456804001074083122140
2025;71(1):29-361615804001074487129173186227268286326344358402446475516559
/22198040010732
www.casopisvnitrnilekarstvi.cz442680400107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
LITERATURA42657001234978134189250318368438498567
1.4257400853648
Asrani493740083416990123161176
SK,688740083336782
Devarbhavi7897400834581113146167207245277309325
H,11337400834457
Eaton1209740083336688124163
J,13917400832436
et.1447740083345669
al.1535740083324860
Burden1615740083357394132167205
of18397400833857
liver191574008315306397118
diseases2052740083385480115147173208235
in23067400831553
the2378740083226095
world.24927400835188110126165178
J268974008324
Hepatol.2732740083458011915242584008322597487
2019;70:151-71.5288400833468100130143176209222252282313331363395405
2.4259400853652
Devarbhavi4969400834581113146167207245277309325
H,8409400834457
Asrani916940083416990123161176
SK,1112940083326781
Arab1213940083406295134
JP,1366940083246065
et14509400833456
al.1526940083324760
Global1605940083446098138171186
burden1810940083397798136171209
of20399400833756
liver211594008314296296117
disease:2252940083385379114146172207220
202324919400833468101136
update.26469400833877116149170204216
J288294008324
Hepatol.42510400834479118151173210226239
2023;79:516-37.67910400833468101136148180214227262293324348380412418
3.42511400853651
Riazi4971140083365183113129
K,64711400833550
Azhari71711400834173111144165181
H,91911400834457
Charette99711400834078110132166189213247
JH,12651140083246982
et136811400833457
al.14451140083324861
The152611400833373108
prevalence16551140083386094127160176211249282316
and199111400833270110
incidence21211140083155386101140175214246280
of242211400833757
NAFLD249911400834587120151197
worldwide:27171140083518911112716642512400835066104139151
a589124008331
systematic6331240083265885108141199231252267299
review9441240083215587102137187
and114412400833269108
meta-analysis.126512400835791113146168200238270285316343358383397
Lancet167412400833265102134168190
Gastroenterol187612400834476102125147183219256278311332369385
Hepatol.227312400834479118150172208224237
2022;7:851-61.252312400833367100134146179189223257288306343373382
4.42513400853651
Younossi49713400833569107145184210237252
ZM,76913400833893106
Golabi8951340083448399131170186
P,110113400833539
Paik11611340083356782112
JM,12931340083247992
et140513400833457
al.14821340083314760
The156213400833272107
global16891340083385391131164179
epidemiology18881340083347389128163221236274290328367399
of230813400833756
nonalcoholic238413400833876114147162194231270308324339371
fatty2775134008318527398131
liver425144008315306297118
disease5601440083385480115146173208
(NAFLD)78514400831964105138169215233
and103514400833270109
nonalcoholic116114400833876115147162194231270308324339371
steatohepatitis15491440083265083115137174212247287320341357379394421
(NASH):198714400831963105139182201213
a2218144008331
systematic22671440083265886109142200233254270302
review.25861440083215587103138189200
Hepatology.2803144008344794251540083397293130146184224256266
2023;77:1335-47.70615400833469101136148181215225255285318351373409441448
5.42516400853650
Rinella4951640083355189124139154187
ME,70116400835488101
Lazarus8211640083316594128149187213
JV.,1054164008324617083
Ratziu11561640083356890121136174
V,134916400833544
et141216400833457
al.14881640083324760
A1567164008341
multisociety162716400835895111133148174213245260295317351
Delphi19971640083468197135174189
consensus220516400833168107133168206233270296
statement25201640083265082104138196231269290
on283016400833775
new42517400833873124
fatty564174008318527398132
liver711174008315306296118
disease8441740083385379114146173208
nomenclature.106717400833876134169207239255287309347368402414
Hepatology.149617400834580119152173210226264304336346
2023;78:1966.185717400833569102136148181214226256286322357371
6.42518400853652
Karen4931840083356890124162
I,67118400831528
Rosolová71518400833674101139155193225258
H,98918400834457
Souček106318400833270109141174204
M,128418400835468
et136818400833456
al.14411840083324760
Metabolický151718400835590112145184223239254286316350
syndrom.18831840083265998137158195254267
Doporučené216618400834684124163184222255288326361
diagnostické25441840083385385124162200227250265297327362
a425194008332
terapeutické4771940083225677110149185223245261293323357
postupy85419400833978105128166205236
pro11111940083386097
všeobecné12291940083315893132172207240278313
praktické15631940083386093123148163195225259
lékaře.18431940083154980113134168181
Novelizace204419400834583115150165180209243275309
2019,237319400833468100131141
Anotace.253419400834180118140173205239251
[cit.2805194008319496486100
2025–01–21].42520400833468101136172209241274306337353365
Available80820400834171104119135167206222257
from:10832040083184078136148
https://www.svl.cz/svl-docs/doporucene-postupy/43/metabolicky-syndrom-2019.pdf.1249204008338598412315016218921026131436737840643945546850053055858361663265469473376579381985489393297199310311063109711351170119312331272129813221360139914301453148515171542159816334252140083225494132148163195225259281308341380419440477535558589623655685696736775795806
7.42522400853645
European4902240083336990128167203235273
Association7822240083416995134166182214235251289327
for11292240083185677
the12262240083215994
Study13402240083325492131162
of152222400833757
the15982240083226095
Liver17122240083324780114135
(EASL),18672240083185194128159178189
European20762240083326990127167202234272
Association23682240083416995134166181213235250288327
for27142240083195678
the28112240083226095
Study4252340083325492131163
of60123400833857
Diabetes6722340083456193132168190224250
(EASD),9362340083195294128173191202
European11522340083336991128167203235273
Association14392340083416995133166181213235250288327
for17802340083185677
the18712340083226095
Study19802340083325391130162
of215623400833857
Obesity222723400834787122149164186220
(EASO),24612340083185194128176194205
European2680234008332699012716720242524400833270
Association5142440083416995134166182213235251289327
for8602440083195678
the9572440083226095
Study10712440083335492131163
of125324400833756
the13292440083215994
Liver14432440083314779113135
(EASL).15972440083185194128159178189
EASL-EASD-EASO180524400833376110141156190233267312335370413447494
Clinical23182440083405670108123155188204
Practice25412440083355689121145160192226
Guidelines278624400834482974252540083387389104141176203
on64425400833876
the7362540083226095
management84725400835790128160199234292327365386
of124925400833857
metabolic132225400835792115147187226241256288
dysfunction-associated16262540083387097117156194226250266304342365397423450488521536568590624663
steatotic23052540083264983115137174196211243
liver2564254008315306296118
disease26982540083385379114146172207
(MASLD).42526400831972114148179225243254
J694264008324
Hepatol.73426400834479118151173210226239
2024;81:492-542.98826400833468101133145180212220255288321341375411443456
8.42527400853652
Liu4952740083314784
Y,59727400833644
Zhong65927400833876114153192
GC,8692740083438497
Tan9842740083336199
HY,11012740083448088
et.12082740083345669
al.12962740083314760
Nonalcoholic137427400834583121154169201238276315331346378
fatty1770274008318527398131
liver1920274008314296296117
disease20562740083385379114146173208
and228227400833270109
mortality240927400835796117142175190205227261
from26882740083194178136
all28432740083314762
causes,42528400833164102128163190203
cardiovascular6432840083316485124139177209242268300338353386407
disease,10652840083385379114146173208220
and130028400833270109
cancer:142428400833264102135168190203
a1643284008331
meta-analysis.169028400835792114147170202240272288319346361387401
Sci21062840083336580
Rep.220228400833570109122
2019;9:11124.233928400833468100130143178191221249277306338351
9.42529400853649
Golabi4912940083448298131170185
P,69329400833539
Paik7492940083356782112
JM,8772940083247993
Kumar98629400833572130162184
A,118629400834155
et125729400833457
al.13302940083324760
Nonalcoholic140629400834583122154170202239277315331346378
fatty1801294008318517397131
liver1948294008315306397118
disease20832940083385379114146172207
(NAFLD)230729400831863104137168214232
and255529400833270109
associated268129400833158841231551712034253040083225595
mortality53630400835896117142175190205228261
in81430400831452
individuals8833040083145291106139155193231263279305
with12043040083516689127
type13473040083225595131
21494304008334
diabetes,15453040083385385124160182216243256
pre-diabetes,18173040083396094117158173205244280302336363376
metabolically220930400835792115147187225241256288321337352383
unhealthy,260930400833775113148180195218256286296
and42531400833270109
metabolically54931400835792114147186225241256288321336351383
healthy94731400833873105120142180211
individuals11733140083155392107139155194231264279305
in149331400831553
the15603140083226095
United16703140083448297119153193
States.18773140083335487109142169183
Metabolism.207531400835489111144183222238253279337350
2023;146:155642.244031400833468101136147178209245257287317349384420453465
10.4253240085367085
Dulai5253240083458499131146
PS,6863240083356881
Singh7823240083334785124162
S,95932400833346
Patel10203240083356788122138
J,117332400832436
et122432400833456
al.12953240083324760
Increased13703240083155385107141173199234274
risk1659324008320366292
of176632400833757
mortality183832400835795117142174190205227261
by211432400833970
fibrosis2199324008317347394132158173199
stage24133240083264982121156
in258432400831553
nonalcoholic2652324008337761141461621942314253340083377590105136
fatty573334008318517296129
liver714334008315296195116
disease:8423340083385278112143169204216
Systematic10703340083326188110143200232253268299
review13823340083205385100134185
and157933400833169107
meta-analysis.169833400835791113145167199236267282313340354380393
Hepatology.210333400834478117149170206222259298329339
2017;65:1557–65.24543340083346899127137172205215245274306339370407440451
11.4253440085366678
Taylor5183440083336191107145167
RS,7003440083356982
Taylor7973440083326091107145167
RJ,9793440083356274
Bayliss10683440083356899115130156183
S,126634400833245
et132634400833456
al.13973440083324760
Association14723440083416995134166181213235250288327
Between18143440083357093146180216254
Fibrosis20833440083324786107145171186212
Stage23103440083335487126161
and248534400833270109
Outcomes260934400834786108139176234269296
of42535400833757
Patients4973540083366789104139177199226
With7393540083587496134
Nonalcoholic88935400834583122154169201238277315331346378
Fatty12833540083326283108141
Liver14403540083324780114135
Disease:15913540083456187122154180215228
A1834354008341
Systematic18913540083336290113146204237258274306
Review221335400833570102118153204
and243335400833169108
Meta-Analysis.255735400835590112145167209247279294326425364008326416781
Gastroenterology.52136400834476103126148185220258280314335372388426466498508
2020;158:1611-1625.e12.104436400833468101135148178208243255285316346374392423454488523535569599629642
12.4253740085366884
Ng52637400834584
CH,6273740083408497
Lim74137400833247105
WH,863374008358103116
Hui9963740083448297
Lim111037400833247105
GE,12323740083447790
et133937400833457
al.14133740083324760
Mortality149037400835593115139172188203225259
Outcomes176637400834785108139176234269296
by207937400833970
Fibrosis21663740083334787108145172187213
Stage23963740083335487126161
in257437400831552
Nonalcoholic2644374008344831211541692012384253840083387692107139
Fatty5803840083326284108142
Liver7383840083314779114135
Disease:8893840083466187122154181216228
A1134384008341
Systematic11913840083336289113146204237258274306
Review151338400833570103118153204
and173438400833169109
Meta-analysis.185938400835490112145167199237270285317344359385398
Clin22743840083405570108
Gastroenterol239838400834477103126148185221259280314335372388
Hepatol.2803384008344794253940083397293130146159
2023;21:931-939.e5.59939400833569102136148183214223258291322340375408441452487522534
13.4254040085366883
Roskilly52540400833574100130147162177209
A,75140400834155
Hicks8234040083445991121150
A,99040400834155
Taylor10624040083326091107145167
EJ,12454040083336072
et.13344040083345669
al.14204040083324760
Fibrosis14974040083324786108145172187213
progression17274040083386097137158192219245260298337
rate20814040083205375109
in220740400831452
a2276404008332
systematic23254040083265885108142200232254269301
review26434040083215587103138189
of284940400833756
placebo-treated4254140083395587119153192231254276298332364386419459
nonalcoholic89941400833876114147162194231270308324339371
steatohepatitis.12854140083264983115137174212247286319341356379394420434
Liver17344140083324780114135
Int.1884414008315537588
2021;41:982-95.198741400833469101133141176206215250285318339374408420
14.4254240085366984
Singh5224240083324785124162
S,69742400833345
Allen7554240083415772107145
AM,91342400834196110
Wang103642400835788126166
Z,121542400833750
et.12784240083345770
al.13614240083324760
Fibrosis14344240083324786108145172187213
progression16604240083396097137158192219246260298337
in201042400831452
nonalcoholic207542400833876115147162194231270308324339371
fatty2459424008318527398131
liver2603424008315306397118
vs273442400833259
nonalcoholic2806424008337764254340083387085117154193231247262294
steatohepatitis:7384340083264983115137174212247286319341356379394420433
a1190434008332
systematic12414340083265986109142200233254270302
review15624340083215587103137189
and177043400833270109
meta-analysis189843400835792115147170202240272288320347361387
of230543400833756
paired-biopsy23804340083397287108142182204244260298337364397
studies.279643400832649874254440083385388115128
Clin5694440083405570108
Gastroenterol69244400834476103126147185220258280314335372388
Hepatol.109544400834479119152173210226239
2015;13:643-54.e1-9;135044400833468100130140170200212247284316338372407420455484503538551
quiz19164440083387691120
e39-40.205144400833469102126162198211
15.4254540085366883
Rinella5274540083355189124139154187
ME,73345400835488101
Neuschwander-Tetri85345400834580118144176214265298336375409431450480511533555571
BA,14434540083357690
Siddiqui15534540083324786125140179216231
MS,180445400835487100
et192345400833457
al.19994540083324760
AASLD207845400834184118149195
Practice22934540083355588121145160192226
Guidance25384540083448297136168206238272
on282945400833876
the4254640083226095
clinical5384640083324762100115147180195
assessment7524640083315885120146173231266304325
and109646400833270109
management122346400835890128160199234292327365387
of162946400833756
nonalcoholic170446400833776114146162194231269307323338370
fatty2093464008318527398131
liver2243464008315306297118
disease.23794640083395480115147173208220
Hepatology.2618464008344791181511732102262644254740083387080
2023;77:1797-835.52147400833468101135147180214224254283317350368404438471483
16.4254840085366985
Vernon5264840083366890128167205
G,74748400834457
Baranova8204840083366990123161199231264
A,110048400834155
Younossi117248400833569107145183210236251
ZM.143948400833893107
Systematic15634840083326289112146204236258273305
review:18844840083215587103138189202
the21024840083226095
epidemiology22134840083347389128163221236274290328367399
and262848400833270109
natural275348400833870921304254940083215469
history5084940083375278101138160194
of71549400833857
non-alcoholic78649400833775114136169184216253291330346361392
fatty1192494008318527398131
liver1337494008315306297118
disease14684940083385480115147173208
and169049400833169108
non-alcoholic181249400833776114137169184216253292330346361393
steatohepatitis22184940083275083115137174213248287320341357379395421
in265249400831553
adults.271849400833271109124146174188
Aliment4255040083415671129164202224
Pharmacol66450400833573105126185217249286302
Ther.98150400833372107128139
2011;34:274-85.113550400833468100128136171206218254287317340376410422
17.4255140085366876
van51651400833265103
der6335140083387394
Poorten74251400833572111132157191229
D,98551400834656
Milner10565140083557085123158179
KL,12505140083356881
Hui13465140083448297
J,145851400832436
et150851400833457
al.15795140083324860
Visceral16545140083365278111144165198214
fat:1882514008319527487
a1984514008332
key20305140083306496
mediator214051400835893132147179201238260
of241451400833757
steatohepatitis24855140083275083115137174213248287320341357379395421
in42552400831553
metabolic49352400835792115147187225241256288
liver797524008314296296117
disease.9305240083385379114146172207220
Hepatology.116552400834479118151173210226264304336346
2008;48:449-57.152652400833468104140152187223235269306340363397430437
18.4255340085366985
Lomonaco52853400833169127165204236268305
R,85153400833649
Bril918534008336577388
F,102453400833238
Portillo-Sanchez10805340083357294118134149164202225257290328360398433462
P,156053400833640
et161853400833456
al.16925340083324760
Metabolic177053400835590112145184223239254286
Impact207453400831572112145177201
of229353400833756
Nonalcoholic236753400834583122154170202238277315331346378
Steatohepatitis276353400833354871194255440083225997132171204226241264279305
in74654400831452
Obese81354400834787123150185
Patients10135440083356789104139177198226
With12545440083587496134
Type140454400833260100136
21555544008334
Diabetes.16045440083466193132168190224251264
Diabetes18845440083456193132167190223250
Care.21505440083397293128140
2016;39:632-8.230554400833468100131144179212225260294327347383396
19.4255540085366982
Borena5225540083357495129168200
W,73755400835767
Strohmaier8195540083325375112151208241256291312
S,114655400833245
Lukanova12065540083316898132170208240273
A,149455400834155
et156455400833456
al.16355540083324760
Metabolic171055400835590112145184223239254286
risk2011554008320366292
factors21185540083185184108145166194
and232655400833270109
primary24505540083396076134166187221
liver2686554008315306397118
cancer28195540083316442556400833870103125
in56556400831552
a633564008332
prospective6805640083396097124163199231255271303337
study10335640083264987126158
of120656400833857
578,700127856400833468101114148182218
adults.151156400833271108124146174187
Int17145640083155374
J1803564008325
Cancer.184356400834073111143176198208
2012;131:193-200.206656400833569100130143173203234242272302335357388422458471
20.4255740085367287
Ajmera53357400834156114149170203
V,75757400833544
Cepin82257400833973112128166
S,100857400833345
Tesfai10745740083326390110143158
K,125357400833549
et132357400833456
al.13995740083324760
A1480574008341
prospective15415740083396097124163199231255271303337
study18995740083264987126158
on207757400833876
the21735740083226095
prevalence22895740083386094126159174209247280313
of262357400833756
NAFLD,269957400834586119150196207
advanced42558400833271104136174207240280
fibrosis,724584008317347394132158173199212
cirrhosis955584008332476890128166193208234
and120858400833270109
hepatocellular133658400833873112145167204236270286301338353386407
carcinoma17625840083316485116131169207266298
in207958400831553
people215158400833974113152168203
with23735840083516689127
type25195840083225595131
22669584008334
diabetes.27225840083385486125160425594008322558296
J536594008324
Hepatol.57659400834479118151173210226238
2023;78:471-8.83059400833468101136147180213226260292325343379393
21.4256040085377285
Younossi53260400833671111150190218246261
ZM,81560400833996110
Golabi94760400834485101135175192
P,116060400833742
de122360400833976
Avila13206040083427491107140
L,148260400833246
et155060400833558
al.16306040083324862
The171460400833374110
global18466040083395595136170186
epidemiology20546040083357592132168228244283300340381414
of249060400833858
NAFLD257060400834588122155202
and279460400833272112
NASH42561400834586120164
in60861400831452
patients6796140083397294109144182203231
with9296140083506688127
type10756140083215595130
21224614008335
diabetes:12776140083395486125160183217243256
A1552614008341
systematic16126140083265885109142200233254270302
review19336140083205487102137188
and214061400833270109
meta-analysis.226861400835792115147170202240272288320347362388401
J2688614008324
Hepatol.273161400834479119152425624008322597487
2019;71:793-801.52862400833468100130143176208217250283316338374409441450
22.4256340085367288
Patel5306340083356789123138
S,68563400833245
Siddiqui7466340083334886125141179217232
MB,99563400835490103
Roman111463400833674132165203
JH,13336340083246982
et143163400833457
al.15046340083324760
Association15816340083416995134166181213235250288327
Between19246340083367193146181216254
Lipoprotein21956340083314686124164186223245278294331
Particles25436340083356788113128160175210237
and279763400833169108
Atherosclerotic42564400834162100135157194221253268303324361383399431
Events8696440083326498137158186
in106864400831553
Nonalcoholic113464400834583121154169201238277315331346378
Fatty15256440083326283108142
Liver16806440083314779113135
Disease.18286440083456187122154180215227
Clinical20696440083405570108123155188203
Gastroenterology228564400834477103126148185221259280314335372388427466498
and279664400833270109
Hepatology.42565400834479118151173210226264304336346
2021;19:2202-4.78665400833468101133141171201214249284318351371408421
23.4256640085367491
Donati53966400834586126160183200
G,76266400834459
Stagni8446640083335690131170187
B,105466400833650
Piscaglia11276640083365279113147188205221255
F,140566400833340
et146966400833458
al.15506640083324963
Increased16376640083145488110146180208244285
prevalence19466640083396297131166183219259292328
of229766400833758
fatty23796640083185376102138
liver25406640083153165101124
in268766400831555
arterial27656640083325581116425674008321387188
hypertensive53467400833769111148170196231271299315349385
patients9396740083397397113149189212241
with12016740083506791131
normal135367400833777100160194210
liver15846740083153165101124
enzymes:172967400833473104139199236264278
role20286740083205976113
of216267400833757
insulin22406740083155482121137154193
resistance.24546740083215684101128153187226260295308
Gut.278367400834484108122
2004;53:1020-3.42568400833470107145158195229242273306340376401435449
24.3047740085367186
Kanwal31517400833568107157190205
F,33747400833339
Kramer3431740083355790148183204
JR,3653740083256175
Li37467400833147
L,38117400833145
et38747400833456
al.3948740083324760
Effect4027740083325170105137161
of42067400833857
Metabolic42817400835590112145184223239254286
Traits458574008332508398120148
on47517400833776
the4845740083226095
Risk4958740083355177107
of50837400833757
Cirrhosis515874008340557698136175201216242
and54187400833270109
Hepatocellular30478400834479118151173210243276292307345360392413
Cancer34768400834072110143176197
in36898400831452
Nonalcoholic37578400834483121153169201238276315330345377
Fatty4150840083326183108141
Liver4307840083314679113134
Disease.4457840083456187122154180215227
Hepatology.47008400834479118151173210226264303335345
2020;71:808-19.50618400833468101135148181213222256292327350381411422
25.3047940085367287
Mantovani31549400835487125147183215248286301
A,34759400834155
Scorletti35509400833264101123139174196220235
E,38059400833346
Mosca38709400835593120152185
A,40749400834155
et.4149940083345670
al.4238940083324760
Complications,43189400834077135174190205237270291307345383410423
morbidity47609400835796117157173211227249283
and50629400833270109
mortality51919400835795117142174190205227261
of54719400833857
nonalcoholic304710400833876114147162194231269308324339371
fatty3433104008318527398131
liver3580104008315296296118
disease.37131040083385379114146173208220
Metabolism.394810400835590112145184223239254280337351
2020;111S:154170.431410400833468101135148178206233262274303333369399428461474
26.30471140085367187
Stahl31541140083325486124140
EP,33141140083326872
Dhindsa34061140083458499137176202236
DS,36611140083467891
Lee377211400833266101
SK,38931140083336782
et.39951140083345669
al.40841140083324760
Nonalcoholic416411400834583122154169201238277315331346378
Fatty45621140083326283108141
Liver47231140083324780114135
Disease48781140083466187122154181216
and511411400833169108
the52421140083226095
Heart:535711400834479111132157170
JACC304712400832464103141
State-of-the-Art32041240083325386108142165204224244267305340363404426450
Review.367012400833570102118153204215
J3900124008324
Am393912400834199
Coll40541240083407792108
Cardiol.41771240083407394132147185201214
2019;73:948-63.440612400833468100130143176210222257293329351388422435
27.30471340085367180
Musso314813400835593119146185
G,335313400834458
Gambino343213400834476135174190228267
R,371913400833650
Tabibian379013400833261100116155171203242
JH,40521340083257083
et415513400833457
al.42331340083324760
Association43141340083416996134167183215237252291329
of466413400833757
non-alcoholic474213400833776115137170185218255294332348364396
fatty5158134008319527499133
liver5312134008315306297118
disease54511340083385430471440083266294121157
with32251440083516790129
chronic33751440083317091129168184216
kidney36121440083304786125161193
disease:38261440083385480116148175211224
a4070144008333
systematic41241440083265987110144203236258274306
review44511440083215689105140192
and466414400833271110
meta-analysis.479514400835894117150173206244277293325353368395408
PLoS522414400833668106138
Med.538314400835591131144
2014;11:e1001680.304715400833468100131143173201209244273305341373404439475487
28.30471640085367288
Mesarwi314816400835489116149170223239
OA,340016400834786101
Loomba351316400833269108166205238
R,376316400833650
Malhotra382616400835486102139177199221254
A.409216400834156
Obstructive416116400834786113136157196228252267299333
Sleep45071640083334883118157
Apnea,467716400834180118153185198
Hypoxia,488816400834475115154184200232244
and514516400833270109
Nonalcoholic52671640083448312115316820023730471740083387692107139
Fatty32011740083326284108142
Liver33581740083314779113135
Disease.35081740083456187122154180215228
Am375117400834199
J3865174008324
Respir39051740083357097136151172
Crit4093174008340617699
Care42071740083407394128
Med.435017400835590129143
2019;199:830-41.450817400833468100130143173203239252286320355379415446455
29.30471840085367387
Sarkar31521840083326688119153175
M,334518400835569
Terrault34321840083336486108142180196219
N,367018400834458
Chan374618400834078111150
W,391418400835868
et400018400833457
al.40751840083324861
Polycystic41551840083357289121153188215239255288
ovary446118400833770103125160
syndrome46391840083265999139161198257293
(PCOS)49501840083195596142176196
is516418400831441
associated52231840083325986125159175207230264304
with30471940083516790129
NASH319319400834486121165
severity33751940083266295130152168191226
and361719400833271111
advanced374419400833272105139178210245285
fibrosis.4046194008317347396134161177203218
Liver42801940083324881116138
Int.4435194008315537589
2020;40:355-9.454119400833469103138151187223237273307340362398410
30.30472040085367389
Hernaez315020400834480102141174209240
R,340420400833550
Lazo34682040083326696134
M,361620400835569
Bonekamp369920400833675114149180215273313
S,402620400833346
et408620400833457
al.41582040083314861
Diagnostic42342040083456194133172211238262278311
accuracy45592040083326596135156190223257
and483020400833271110
reliability4955204008321557287120160176192207230265
of523420400833757
ultrasonography5306204008337537698132159198304721400833877117139172212251283
for33452140083195779
the34402140083216096
detection35522140083387396131164189205244283
of385021400833757
fatty39232140083185275100134
liver:4073214008315306499120135
a4223214008332
meta-analysis.427121400835793116149173205244277293326353369396410
Hepatology.469721400834479119153176213230269309342352
2011;54:1082-90.506521400833469101130139174210223254286322356377413449463
31.30472240085367083
Šmíd314522400833290106146
V,330522400833646
Dvořák336522400834680118140174205
K.358422400833551
FIB-436502240083324784107145
index38092240083155393129161
–3985224008335
interpretace40342240083155376110132173195230253286319353
získaného44022240083284471102136175210249288
výsledku47052240083326794110146186217256
a4975224008332
doporučení502222400833877117156179218250285323339
dalšího53762240083387187114129304723400833877
postupu313923400833978106129168208247
2023.340123400833569103138152
Doplnění356823400834585125142180216254270
Doporučeného385423400834584125164186225258292331367406445
postupu431423400833978106130168208247
České457723400834074102132167
hepatologické475923400833874114147170207224263303319352382417
společnosti519223400832665105122157190229268295319335
ČLS304724400834072107
JEP31702440083245894
pro32792440083396199
diagnostiku33942440083385486126165204231255271302341
a3750244008332
léčbu37982440083145083123162
NAFLD.397524400834587120152199211
Anotace.420124400834180119142175208242255
[cit.4472244008318496588102
2025–01–21].459024400833469102138175213245279311343359372
Available497824400834172105121137170210227262
from:52562440083184179138151
https://www.ces-hep.cz/file/746/doplneni-dop-postupu-fib-4-schvaleno-05-12-2023.pdf.54222440083386085304725400833866791061271782322862973293643914124524875275405726036326506676837187447818118488749109489881005104310781117113211551196123512751298133913781405142914671507154615681587160416431667170417281755178818261858189119071942198120202043208121162138216922002221225222872320235523682408244824682480
32.30472640085367188
Wong314926400835794134173
VW-S,333726400833597119151164
Wong351626400835794133173
GL-H,37032640083447793139153
Chan387026400834078111150
RS-M,40352640083356992149163
et421326400833457
al.42842640083324861
Beneficial436026400833571110145164181213229262278
effects46522640083345473108142166195
of486126400833757
lifestyle4933264008315305085113137171188223
intervention51712640083145375109131167202240263279317356
in304727400831553
non-obese311427400833776115138178218254281317
patients34452740083397294110145184206234
with36932740083506790128
non-alcoholic383527400833876115138171187219257296334351366399
fatty4248274008318527499133
liver4396274008314306398119
disease.45292740083385481116148175211224
J4767274008324
Hepatol.480527400834479119153175212229242
2018;69:1349-56.506127400833469101133145182216230260290326360384418453467
33.30472840085367287
Berzigotti31522840083357193124141180219242267283
A,345328400834155
Albillos35262840083415897113129145184211
A,375528400834156
Villanueva3829284008336536984117156194230263297
C,414328400834054
et421528400833457
al.42902840083324861
Effects43692840083335371107140165193
of458028400833757
an465528400833271
intensive47442840083145375110148175191224259
lifestyle5021284008315315186113137172188224
intervention5263284008314537511013116720224130472940083223876115
program31782940083396199139161195253
on344729400833877
portal354029400833878100125159175
hypertension373129400833769109146167193227266293309347386
in413329400831553
patients42022940083397395111146185207236
with44542940083506790129
cirrhosis4598294008332476992131170197213240
and485329400833271111
obesity:498029400833777113141156180214228
The522429400833372108
SportDiet53482940083327211213415930473040083456297120
study.31843040083265088128161171
Hepatology.337230400834480120154176214230269309342353
2017;65:1293-305.374230400833469101131142178213224255285320354376409444479492
34.30473140085367490
Hashida315531400834477104143159198231
R,340431400833650
Kawaguchi347331400833469120154193232265303319
T,381031400833342
Bekki387031400833672103135152
M,404031400835469
et412731400833457
al.42023140083314861
Aerobic42813140083417698136176193225
vs.45243140083326074
resistance4616314008321568399125149183221254289
exercise492331400833466101123154170197233
in517431400831453
non-alcoholic52453140083387711613917218822125830473240083387793109141
fatty32053240083195375100134
liver3356324008315316499121
disease:34943240083385380116149176212225
A3735324008341
systematic37933240083265987111145204237260276308
review.41183240083215588105140192204
J4338324008324
Hepatol.437932400834480120154176214230244
2017;66:142-52.464032400833469101131142178214228258290323344379413426
35.30473340085367287
Mai315333400835488104
BH,32753340083368195
Yan338833400833666105
LJ.35113340083326073
The360233400833373109
negative372933400833874114147169185219254
and400133400833271111
detrimental41303340083387497119135194230268291324340
effects44893340083345473108142167195
of470333400833757
high47793340083375392131
fructose49293340083184180113138175203239
on518633400833877
the52813340083226197
liver,5396334008315316499121132
with30473440083506790128
special318934400832666102135151183199
reference34033440083205574109131166204237271
to368834400832259
metabolic376234400835792115148188228244260292
disorders.40683440083385481119141180215237265279
Diabetes,43613440083466294134170193227254268
Metabolic464334400835590113146186225242257290
Syndrome494734400833263102142163201260295
and525734400833170109
Obesity5381344008346871233047354008326426599
2019;12:821–6.316335400833469101132146177207220256290322356394408
36.30473640085367389
Chen315136400834078114153
YP,33183640083357278
Lu341036400833169
FB,34943640083326881
Hu358936400834483
YB,36863640083357386
et378736400833356
al.38583640083324861
A3934364008341
systematic39893640083265987111145204237259275308
review43113640083215689105140192
and451836400833170110
a4642364008332
dose-response468836400833877105140164187221249289328367394430
meta-analysis513236400835893116150173206244277294326354369396
of304737400833757
coffee31213740083316989108143179
dose331737400833877105140
and347437400833270110
nonalcoholic360137400833776116149165197235274313330346378
fatty39963740083185275100134
liver4147374008315306499121
disease.42843740083385481117149177212225
Clin45263740083405671110
Nutr.465337400834483106128139
2019;38:2552-7.480937400833469101132146181217230265301334368389421428
37.30473840085367181
Parra-Vargas31473840083356890112146169205237259298331358
M,352438400835469
Rodriguez-Echevarria361238400833574114136152192230266296318353385424460493526548571587620
R,425138400833550
Jimenez-Chillaron43203840083244098134172208238261304343359375390423445483522
JC.48613840083246680
Nutritional496038400834483106128145168184222262295311
Approaches528938400834181122144182216304739400833170106133
for31973940083195779
the32933940083226197
Management340739400835487126159199235293329368390
of381439400833757
Nonalcoholic388839400834584123156172205243282321338353386
Fatty42913940083326385110144
Liver44533940083314780115137
Disease:46073940083466289124157184220233
An485739400834180
Evidence-Based49543940083336582121157196229263287325358386421461
Review.54333940083357130474040083324883135147
Nutrients.321140400834483106128144180219241269284
2020;12:1-22.351140400833469103138151182213226256276307343356
38.30474140085367390
Singh31524140083324886126165
A,333241400834156
Sohal340341400833372111144160
A,357841400834156
Batta36494140083366992117150
A.381541400834156
GLP-1,388641400834477113135166176
GIP/GLP-1,40774140083446096118162194231253284294
and438641400833270110
GCGR/GLP-1451141400834486128165193237269306328359
receptor48854140083215689124164186224246
agonists:514741400833171110149165192216244257
Novel54194140083458430474240083326783
therapeutic31514240083226196118152192228267290306339
agents351142400833271107146168196
for37294240083185779
metabolic382942400835793116150190229246261294
dysfunction-associated41444240083397199120159198231255271310349372405433460499532548581603638678
steatohepatitis.48434240083265085117140177217252292326348364387403430445
World530942400835794117133173
J5503424008324
Gastroenterol.304743400834477104128150188225263286320342380397410
2024;30:5205-11.347443400833469102135148183218232268302337372394426454464
39.30474440085367286
Newsome315344400834580132160199258294
PN,34664440083368194
Buchholtz358044400833574107146184223240263294
K,389444400833550
Cusi396444400834077104120
K,410444400833550
et417444400833457
al.42504440083324862
A4332444008341
Placebo-Controlled43934440083355083116150190230254297335374396419457473489524565
Trial49774440083335167100116
of511344400833757
Subcutaneous519044400833270110144182205239278313304745400833776103
Semaglutide317245400833268127160200216254277293333369
in356345400831453
Nonalcoholic363845400834483123156172205242282321337353386
Steatohepatitis.40454540083335589122144182221257297331353369393409435450
New451745400834480132
England467145400833271111127160199238
Journal493145400832463102124163197213
of516545400833858
Medicine.524545400835490130146179195233269282
2021;384:1113-24.304746400833469103135144179214251264295323351382405436469482
40.30474740085367389
Loomba315047400833168107165205238
R,340247400833549
Hartman34654740083437697122180213251
ML,372947400835487101
Lawitz384347400833165116132154185
EJ,40424740083325971
et412747400833456
al.41974740083324761
Tirzepatide42714740083335071102136175209230246285320
for46054740083185678
Metabolic469647400835489112145184223239255287
Dysfunction-Associated49974740083447710512516320223425827431235037341444246950830474840083314780102137177
Steatohepatitis32414840083325488121143181220256296329352368391407434
with36924840083506690128
Liver38374840083324881116138
Fibrosis.39924840083324887110148175191217232
N4240484008345
Engl430248400833271111127
J4445484008324
Med.448648400835590131144
2024;391:299-310.464748400833469103135148184217250259295330366390424455487501
41.30474940085366982
Sanyal314449400833266105136170186
AJ,33454940083416881
Bedossa344149400833571111150178205239
P,369549400833540
Fraessdorf37504940083325386122150177217256278300
M,406549400835468
et414849400833457
al.42204940083324862
A4296494008341
Phase435249400833573106134169
24536494008334
Randomized458549400833669108147186245261291326366
Trial4966494008332506799115
of509649400833757
Survodutide51684940083337193128166207245268284324359
in304750400831553
MASH311750400835497132176
and331050400833270110
Fibrosis.34375040083324888110148175191218232
N3686504008344
Engl374750400833371111127
J3891504008324
Med.393250400835490130144
2024;391:311-9.409350400833469102135147183217250259295326355374410421
42.30475140085367086
Kelly31485140083356985101133
MJ,32945140083548193
Pietranico-Cole34015140083355085107129162200216248285309352389405440
S,385551400833246
Larigan39145140083326587103142174212
JD,41405140083247082
et423651400833356
al.43065140083314760
Discovery43805140083456187120157189224245280
of467351400833757
2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile47445140083345474109122157179220235268306322360382419443480503524557580596622661701723760304752400833971871101481722132442823063373473834074484645035345735956336737057287447848178478639029259589811013103010691100113411531193123212681307133813551375139814311443147915021543155915981629166716911722173517711784182018321868189119141949197219942027206620972137215821962216224922592295230923442363238624082424245730475340083284583119143181205239273294335374414429452475491507542
(MGL-3196),361153400831973118151167200231262298317329
a3962534008332
Highly401553400834460100139155187
Selective42245340083326884120153178194227262
Thyroid450853400833372104126164181220
Hormone475053400834483105164203243278
Receptor505053400833571104139179201239261
β5333534008338
agonist53935340083327111030475440083385380104
in316854400831453
clinical32385440083314763101117150183199
trials3454544008322446093109135
for36065440083195779
the37025440083226096
treatment38155440083224478111133192228267289
of412154400833757
dyslipidemia.41955440083387098114130170186225261320335368382
J4594544008324
Med463554400835490130
Chem.478254400834078114173187
2014;57:3912-23.498554400833569102134146182216227263297329360381413448461
43.30475540085367288
Harrison31505540083447799121138165204243
SA,34085540083327489
Bedossa351255400833571111150177205238
P,376555400833641
Guy382155400834382115
CD,39515540083408698
et406455400833457
al.41365540083314761
A4212554008341
Phase426855400833573106133169
3,445255400833447
Randomized,451455400833569107147186245261291325366379
Controlled490855400834078117139161199216232267307
Trial52305540083335167100116
of536155400833757
Resmetirom543355400833571304756400832684120143159181219278
in334256400831453
NASH341256400834486121165
with35945640083516790129
Liver37405640083314780115137
Fibrosis.38945640083324888110148175191218232
N4143564008344
Engl420456400833371111127
J4348564008324
Med.438956400835490130144
2024;390:497-509.455056400833469102135147183217253267302336370389424458494506
44.30475740085367490
Zhou315157400833776114152
H,331757400834457
Toshiyoshi33885740083336794132148180218245283298
M,370057400835468
Zhao378257400833876108147
W,394357400835767
et402457400833456
al.40945740083324861
Statins41695740083325487109125163189
on437257400833776
nonalcoholic446257400833776114147163195232271310326341374
fatty4850574008318517498132
liver4996574008315306398119
disease:51295740083385480115148174210223
A5366574008340
systematic54205740083265986304758400832256115148170186219
review32835840083205588104140192
and349158400833271111
meta-analysis361858400835893116150173206245278294326354370396
of403158400833757
14410558400833466
RCTs.418858400833577113136150
Medicine.435558400835490130146179194233269282
2023;102:e33981.465358400833469103138150181213247260295330364398434466476
45.30475940085367287
Lee315359400833166102
Y,327459400833544
Doumouras333659400834685124182221260282316343
AG,36985940083418498
Yu381559400833571
J,390459400832437
et396059400833457
al.40355940083324862
Complete411559400834078137176193229252286
Resolution44195940083367299138155193216232271310
of474759400833858
Nonalcoholic482359400834584123156172205242282321337353386
Fatty52275940083326385110144
Liver53905940083314781116138
Disease30476040083456288124157184220
After32846040083416086121142
Bariatric34446040083356991107140162184200233
Surgery:36946040083337193132167189224238
A3949604008341
Systematic40076040083336391115149208241264280312
Review433660400833671104121156208
and456160400833271111
Meta-analysis.468960400835490113147170203241274290323351366393407
Clin51146040083395571110
Gastroenterol52416040083437710412815018822426330476140083225678116133
Hepatol.319661400834480120154176214230244
2019;17:1040-1060.e11.345761400833469101132146176207217248280317354378410442478514528563594622632
46.30476240085367491
Kehagias315662400833570109142182197230257
D,343262400834557
Mulita350762400835493109125148181
F,370762400833239
Drakos376462400834568102132171198
N,et39806240083455994117
al.41166240083324861
Bariatric41966240083356991107140162184201233
surgery:44486240083266486124160182217231
blessing46976240083395591119146161200240
or495562400833760
sometimes503362400832665124160183199257293321
curse53726240083317091119155
for30476340083185779
the31436340083216096
liver?3256634008314306398120143
Prz34166340083355788
Menopauzalny.352163400835490129168208242280310344360399430441
2021;20:108-11.397963400833468102134143179214227258290326350381409420
47.30476440085367180
Král31466440083355892108
J,327264400832437
Machytka332864400835487120159190216247281
E,362764400833347
Horká369264400834483105137171
V,388164400833646
et394564400833457
al.40206440083324862
Endoscopic410064400833371111150177210248288304337
Treatment44556440083335186118141200235274296
of477064400833757
Obesity484564400834788124152167190225
and508864400833271110
Nutritional521764400834483106128145168184222262295311
Aspects304765400834170109145179204232
of329665400833757
Bariatric33706540083356991107140162184201233
Endoscopy.362065400833371111150177210248288320331
Nutrients.396765400834583107129145181219242270284
2021;doi:426865400833469103135144183222238251
10.3390/nu13124268.45366540083346679116149183220245282320351382413444476510544580594
48.30476640085367491
Jirapinyo3153664008324406295135152190221260
P,342866400833540
McCarty348366400835487129163185210244
TR,37426640083337085
Dolan384266400834585101134173
RD,40306640083358294
et.41386640083345771
al.42246640083324862
Effect43016640083325271106139164
of448066400833757
Endoscopic455266400833371111150177210248288304337
Bariatric49046640083356991107140162184201233
and515266400833271110
Metabolic52776640083559011314718722630476740083153063
Therapies312767400833373109131164204220256283
on342767400833877
Nonalcoholic352167400834584123156172205242282321337353386
Fatty39246740083326285110144
Liver40856740083324881116138
Disease:42406740083456289124157184220233
A4490674008341
Systematic45486740083336391115149208241263279312
Review487767400833671104121156208
and510267400833271110
Meta-analysis.5230674008354901131461702032412743047684008315477591117132
Clin31956840083405672110
Gastroenterol332268400834477104128150188225263286320342380397
Hepatol.373568400834580120154176214231244
2022;20:511-524.e1.399668400833469102138151187221235271303331351385419452465500531541