850
HLAVNÍ506722001005185134178232252
TÉMA533422001003981147194
Současné377933001003776114145181210247283
možnosti407833001005998128166205235262278
biologické43723300100385392107146185200230265299
léčby46873300100155081120155
bronchiálního485833001003862100138169206222256272309325364403
astmatu52773300100346390151186212251
|5584220010018
223564222001003674109
/36008040010732
Vnitř3677804001074592111139166
Lék.3862804001074184122140
2025;71(4):218-2234022804001074487128172185226267286327349363407447486514553597641
/47088040010732
VNITŘNÍ48058040010746106127172221280301
LÉKAŘSTVÍ5128804001074084130188235279325377399
www.casopisvnitrnilekarstvi.cz42580400107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
3.4255500853651
Settipane494550083326890114129168201240275
RA,787550083357892
Kreindler898550083345791106144183198233254
JL,1171550083245670
Chung12595500834078115153192
Y,14705500833543
Tkacz1532550083326397129160
J.17105500832437
Evaluating1765550083336497113150183204220258297
direct2080550083385374108141165
costs2263550083326995118146
and24275500833270109
productivity2555550083386097137174206231246278294317350
losses425650083155380106141168
of6066500833757
patients676650083387193108143181203230
with919650083516689127
asthma1059650083325882120177210
recieving1282650083215587102137169185223262
GINA15576500834459104146
4/51716650083345992
therapy1821650083226095116149189220
in20546500831552
the2119650083226095
United2227650083448297119153193
States.2433650083325386108141168182
Ann26286500834179117
Allergy27586500834156711061284257500833870
Asthma510750083416992131188221
Immunol7467500831573131168206244260
2019;123(6):564-572.e.3.10227500833468100130143173203237256289307319354388425448482515550562597609645657
4.4258500853651
Cisternas491850083405581104138159198230257
MG,7638500835499112
Blanc890850083355183121153
PD,1058850083368191
Yen11648500833667105
IH,1284850083145972
et13718500833456
al.1442850083324760
A151785008341
comprehensive15738500833168126165187221259294332359373406440
study2028850083264987126158
of22018500833857
the2273850083216095
direct2382850083395475109142166
and25638500833169108
indirect2686850083155392107128162195219
costs425950083316895118146
of5869500833757
adult6589500833271108124146
asthma.819950083325982120178210223
J105895008324
Allergy1097950083415772107128166198
Clin1310950083405670108
Immunol14349500831472130168206244260
2003;111:1212-1218.17099500833469105138149179207235243273303334364385415445477508521
5.42510500853650
Chung48710500834077114151190
KF,6891050083356874
Wenzel77510500835790127156189205
SE,9921050083326477
Brozek10811050083355693121154184
JL,12771050083245669
et135910500833355
al.14261050083324760
International14981050083155273106127165197218233271308340355
ERS/ATS186610500833267100125161190223
guidelines21011050083387590128162178192230264290
on240410500833775
definition,24911050083387289106143158180195232270282
evaluation278610500833465984251150083155285106122160198
and63811500833270109
treatment7631150083214377109130189224262283
of106211500833756
severe11331150083276294128149183
asthma.13321150083315881119177209223
Eur15701150083336990
Respir16761150083357097136151173
J.186411500832436
2014191611500833468100131
Feb;43(2):343-73.206211500833367106118153185203237255267302338370392424458470
6.42512500853652
Skov49812500833363101134
I.R.,65312500831528668194
Madsen76812500835588127154190228
H.,10171250083455972
Henriksen111012500834480119140156187216252290
D.P.,14211250083465795100113
Andersen155512500834180120155177205240279
J.H.,1855125008324378497110
Pottegård19861250083367395120154195227249288
A.,22951250083415669
Davidsen238512500834679111127166193229267
J.R.2673125008325377590
Low278412500833169121
dose42513500833876103138
oral5831350083385992108
corticosteroids7111350083316890114130162198225248282303341356395421
in115213500831553
asthma12251350083325982120178210
associates14561350083315884123155171203224258285
with17611350083516689127
increased19081350083155385106140172199234273
morbidity220213500835795117157172211226249282
and250513500833169109
mortality.263413500835796117142175190205227261271
Eur4251450083336990
Respir5311450083357097136151172
J.71914500832436
2022;60(3)77114500833468101136148184219239272289
7.42515500853645
Heatley48515500834479111133148183215
H.,7151550083445770
Tran8001550083335083121
T.N.,9361550083334288102115
Bourdin106615500833574112133171186224
A.,13051550083415669
et138915500833456
al.14601550083324860
Observational153615500834786113148169204237259274312351383398
UK194915500834480
cohort204415500833168107145166191
study22501550083265088127159
to242415500832158
describe24981550083387399132153169208243
intermittent275615500831553751081304251650083577295119153191213
oral6561650083375992107
corticosteroid7821650083316889114129161198225248282303340356395
prescribing11951650083396094121153175190229245283322
patterns15351650083397294118152173211238
and179116500833270109
their19181650083226095110132
association20681650083325885123156171203225240278316
with24031650083506688127
adverse254816500833271103138159186221
outcomes2788165008337759842517500833168126161188
in62917500831452
asthma.6961750083325982120178210224
Thorax.93517500833272110132165196210
2023;78(9):860-867.116017500833469101136148181214233265283295330366401425461496529535
8.42518500853652
Brusselle4901850083355695121147182197212247
GG,75018500834388101
Koppelman86418500833472111150186201259291329
GH.120618500834388101
Biologic13201850083355088104142181196228
Therapies156118500833271106127160199214249275
for18491850083185677
Severe19391850083326799133155188
Asthma.21401850083416992130187219233
N2385185008345
Engl244318500833270109124
J2580185008324
Med.261718500835489128141
2022277118500833468101135
Jan4251950083245694
13;386(2):157-171.5351950083346475110145180199233251263292322356374405435467476
9.42520500853649
Hanania49420500834476114147185200232
N.A.,74520500834558102117129
Wenzel89420500835790128158192207
S.,11212050083324558
Roseń119820500833674101136174
K.,13912050083355063
et147320500833457
al.15492050083324760
Exploring162820500833366105121159181196234273
the19212050083215994
effects20352050083345372107139164191
of224620500833756
omalizumab232220500833795127143158187225283315355
in269620500831552
allergic27682050083324762971184252150083385486
asthma:5322150083325983122180213226
an77821500833371
analysis87021500833271103119151179194221
of111121500833858
biomarkers11902150083395493152185206237272294321
in153221500831554
the16062150083226197
EXTRA172321500833374110148191
study.19352150083265088128161171
Am2127215008341100
J2248215008324
Respir22932150083367198138154175
Crit24892150083406278101
Care26102150083417496130
Med.276121500835591131144
2013;187(8):804-811.42522500833468100130141172203236252286304316350386422445481513540550
10.4252350085367085
Casale5252350083407399132148183
T.B.,723235008333427992105
Luskin8432350083316895125141179
A.T.,1037235008341568695108
Busse116023500833673100126161
W.,13372350083576780
et143223500833456
al.15042350083314760
Omalizumab1579235008347106138153168197236293326365
effectiveness19592350083345473107140164179212246284319346373
by234723500833970
biomarker24322350083395492151183204235269290
status27372350083275083104142169
in42524500831552
patients4902450083397193108143181202230
with7322450083516688126
asthma:8712450083325881119177209221
evidence11052450083346682120155193225258
from13762450083184077135
PROSPERO,152424500833570118150185217252300311
a1848245008331
prospective18922450083396097124162198230254269302336
real-world22412450083205486101123175212234249288
study.25422450083264987126157167
J2722245008324
Allergy2759245008341567110612742525500833870
Clin5102550083405671108
Immunol63425500831572130168206244260
Pract.9092550083355689121145159
2019;7(1):156-164.e1.108325500833468100130143176192224238250280310344368399430466479514543553
11.4252650085366678
Menzies-Gow52026500835490128157173207234255302340391
A,92826500834156
Flood-Page10012650083324785123163185222254293328
P,134626500833540
Sehmi140326500833267105163178
R,159826500833650
et166526500833456
al.17382650083324760
Anti-IL-5181526500834179101116138155186202236
(mepolizumab)206826500831874109148187203218247286343376415432
therapy25172650083226095116149189220
induces275426500831552911294252750083316592
bone53627500833977116151
marrow70627500835790111133170221
eosinophil9462750083347399114152190230269284299
maturational126427500835790111149170203225241279317349365
arrest16482750083325375109135159
and182627500833270109
decreases195427500833873105127161193219254281
eosinophil22542750083347399114152190230269284299
progenitors25722750083396098137172210225248284306333
in42528500831553
the4932850083216095
bronchial6032850083396097136168206221253268
mucosa88728500835795127164191224
of112628500833757
atopic11982850083325390130146177
asthmatics.13912850083325881119177210231247279306320
J1726285008324
Allergy17662850083415671106127165198
Clin19792850083405570108
Immunol210228500831573131168206244260
2003;111:714-719.237828500833468104137149179206234243276308339362394426456467
12.4252950085366884
Ortega5272950083476993127167199
HG,74429500834488102
Liu8642950083314684
MC,96529500835596108
Pavord10912950083356799136158196
ID,13052950083156071
et139429500833456
al.14682950083324760
Mepolizumab154629500835489128167183198227265323356395
treatment19592950083214377109130188223262283
in226029500831452
patients23302950083397293109143181203231
with25782950083516789127
severe27232950083266193128149183
eosinophilic4253050083347399114152190230268284299314346
asthma.7863050083325881120177210223
N1024305008345
Engl108430500833371110125
J1225305008324
Med126430500835490129
2014;371:1198-1207.140830500833569100131143178210243251281309339374397428457492524530
13.4253150085377085
Pavord53231500833669101140162201
ID,7543150083156274
Korn8493150083367496136
S,100631500833347
Howarth107431500834584137170192218257
P,135231500833641
et141431500833558
al.14933150083324862
Mepolizumab157631500835692132172188204234273332366406
for20033150083195880
severe21043150083276396131153188
eosinophilic231331500833575102118157196237276292308323356
asthma26903150083336084123182216
(DREAM):42532500831967105141186244263277
a729325008333
multicentre,78932500835999115139156190225265288311347361
double-blind,117732500833979119161178215239281299315355396410
placebo-controlled16143250083405791125161202243268304343383406429468486502539581
trial.2222325008322456296113127
Lancet.237632500833268108142177201216
2012261932500833571105137
Aug278332500834281122
18;380(9842):651-9.4253350083346577112147182202234269305338356368403437468487522533
14.4253450085366984
Chupp52634500834078115154194
GL,7363450083447690
Bradford8423450083365790129148186208246
ES,11043450083336780
Albers12003450083415695131152179
FC,13963450083327285
et149834500833456
al.15703450083324861
Efficacy1647345008333506886118151183217
of188034500833757
mepolizumab195334500835793132171187201231269327359398
add-on236834500833171110132172210
therapy25943450083226095116149189220
on283034500833876
health-related42535500833772104120142180202224258274306328361401
quality83935500833875108123138160194
of104635500833756
life1115355008315304984
and121235500833169108
markers133335500835890111142176197224
of157035500833757
asthma16403550083315881119177209
control186235500833168106128149186202
in207735500831553
severe21433550083266193127148182
eosinophilic233835500833473100114152190230268283299314345
asthma26963550083325982120178210
(MUSCA):42536500831972116148189232251262
a708365008332
randomised,7603650083215492131169227242269304343356
double-blind,113636500833876115154170205228268284299337376388
placebo-controlled,15453650083385486119152192230254287324363384406443459474509549561
parallel-group,21273650083387192125141156191206229269290328366405417
multicentre,256436500835795111133148180214252274295329341
phase42537500833977109136171
3611375008335
b658375008338
trial.712375008321435890106119
Lancet84637500833165103135169191
Respir10523750083367197136152173
Med124037500835590129
2017;5:390-400.138537500833468100129139174185220253289313350386422434
15.3047550085366881
Bel3142550083357085
EH,3240550083337688
Wenzel33415500835890128156190205
SE,3559550083326476
Thompson36495500833271108166204230268306
PJ,3968550083355465
Prazma4046550083355588116174206
CM,42655500834094107
Keene43855500833569104141175
ON,45745500834691104
Yancey46915500833564101133166196
SW,4901550083329099
Ortega5013550083476892125164195
HG,52225500834488100
Pavord5336550083356697134154192
ID;3047650083156072
SIRIUS313365008332468196140171
Investigators.3318650083145282116142164179217249270306327353366
Oral36986500834768100115
glucocorticoid-sparing3827650083385289121157189225246270285316352367405427453491523544559596634
effect4475650083345372105137161
of46496500833856
mepolizumab47196500835792130168184198226264321353391
in51246500831452
eosinophilic5189650083347298112150187226264278293307338
asthma.3047750083325880118175206219
N328075008345
Engl33387500833370108123
J347575008324
Med.35137500835589128140
20143667750083346899129
Sep38107500833367105
25;371(13):1189-97.3929750083346979113144176190221251267278307334365398421455488493
16.3047850085366883
Harrison3141850083447595116130155192230
T,33828500833240
Canonica34338500834071108145183197227259
GW,370385008344100109
Chupp38238500834077113151189
G,40238500834456
Lee4090850083316499
J,42008500832435
Schleich42468500833263100114148162193230
F,44878500833237
Welte45358500835789104125158
T,47048500833240
Valero4755850083356580113134170
A,49368500834054
Gemzoe50018500834377134162198233
K,52458500833448
Maxwell5304850083548511616820130479500831529
A,30929500834154
Joksaite3162950083246191119152166188221
S,33999500833244
Yang34599500833564101139
S,36149500833244
Howarth36749500834482132164184208246
P,39359500833639
Van39909500833666103
Dyke41099500834577107141
MK.42659500835590104
Real-world43859500833569100115137188225246261299
mepolizumab46999500835892131169184198227264321353392
in51069500831552
the5173950083225994
prospective528295008339609612216119522730471050083223668102
severe31631050083266092125146179
asthma33561050083325880118175206
REALITI-A357610500833669111142156190205227268
study:38581050083264886124155168
initial4040105008315526688102134148
analysis.420210500833270101116147173187213226
Eur44421050083326888
Respir45441050083367096134149170
J.472810500832435
2020477710500833568100134
Oct492410500834779103
15;56(4):2000151.50411050083346373108141159192208220254287323358389419449458
17.30471150085366775
Bleecker31371150083355084119151181214235
ER,33861150083336881
FitzGerald3482115008332466898143178198230245283
JM,37801150083247891
Chanez388611500834077109146180209
P,411011500833539
et416411500833455
al.42341150083324659
Efficacy4307115008333506886117149181214
and453511500833269108
safety46581150083265876110132165
of483811500833755
benralizumab490811500833974111131164178193221259316347386
for53091150083185576
patients5400115008338719210630471250083347192119
with31791250083516687125
severe33171250083266092126146179
asthma35101250083315780117174206
uncontrolled372912500833774106142180201221258273288322361
with41031250083506587124
high-dosage42401250083385290128149189227253285323358
inhaled46111250083145289120135169208
corticosteroids48321250083316889112127158195221243276297333348386412
and525712500833169107
long-53771250083155290129150
-acting30471350083215284107121158197
β2-agonists32551350083387190122160197235249274297323
(SIROCCO):3590135008318496398145185223267284296
a3897135008332
randomised,39401350083215390128166223237263297335347
multicentre,429913500835794108130144176208246266287320331
placebo-controlled46421350083385385116149187225248281317354375396432447461495534
phase518813500833876107133167
35367135008334
trial.5412135008322425788103115
Lancet.304714500833164101133166187200
201632611450083346899129
Oct340414500834779102
29;388(10056):2115-2127.35201450083346880114148183201232263298332365382394428459486515537567598627659664
18.30471550085366984
FitzGerald3149155008332476898143178198231245284
JM,34501550083247991
Bleecker35591550083355085119151181214235
ER,38111550083336881
Nair39101550083447690111
P,403815500833639
et409515500833456
al.41681550083324759
Benralizumab,424515500833570107127160174189217254312343382393
an465615500833269
anti-interleukin-547431550083316990104126141178199232253268302339368384421443476
receptor52371550083205486119157179215236
α5491155008337
monoclonal304716500835795133170202217254292324338
antibody,33991650083326990105143181220252261
as367416500833157
add-on374516500833270109130169207
treatment39661650083224276107128185220257278
for42581650083185576
patients43481650083397192107141178199226
with45881650083516587125
severe,47271650083266092125146179190
uncontrolled,493116500833775106142180201222258274288322361373
eosinophilic5318165008334729811214918730471750083397691105120151
asthma32091750083325881118175207
(CALIMA):34271750083195799131145199241259270
a3709175008332
randomised,37521750083215390129166224238264298337349
double-blind,411217500833876113152167201223263278292329368380
placebo-controlled45031750083395486117150189227249282318356377398434450464498537
phase505117500833977109134169
35231175008334
trial.5277175008322425789103115
Lancet.5404175008331641023047185008331648698
201631591850083356899129
Oct330218500834779103
29;388(10056):2128-2141.34191850083346779114147182200231262297331364382393427458487520542573603634663672
19.30471950085366982
Nair31451950083457792113
P,327419500833640
Wenzel333019500835891129158192208
S,355419500833345
Rabe361519500833669108143
KF,37751950083346874
et386519500833457
al.39381950083324760
Oral401419500834769102117
glucocorticoid-sparing41471950083385491123160193230252276291323360376415437464503536557573610649
effect48131950083345372106139163
of499219500833857
benralizumab506519500833974112134167182197226264322354394
in547519500831452
severe30472050083266193128149183
asthma.32452050083325982120178210223
N3484205008344
Engl354420500833270109124
J3684205008324
Med.372320500835590129142
2017;376(25):2448-2458.388120500833468100129139174206238257291326344356391423460496519550581614648662
20.30472150085367287
Castro31482150083407399122144181
M,334321500835468
Corren34242150083407799121155193
J,363121500832436
Pavord36812150083356798136157195
ID,38902150083156171
et397521500833456
al.40452150083324760
Dupilumab411921500834584123138154191249281320
efficacy4453215008334537088120153185219
and468621500833169108
safety48082150083265978113135169
in499021500831553
moderate-to-severe50572150083579513517019122424628030332536238541244730472250083326687121
uncontrolled318422500833775107144182204225262278293328368
asthma.35672250083325882120178210223
N3806225008344
Engl386622500833270109124
J4006225008324
Med.404522500835590129142
2018;378(26):2486-2496.420322500833468100131143178210243262296330348360395427463498522553585618653666
21.30472350085367082
Rabe314623500833568107143
KF,33062350083356975
Nair33982350083447792113
P,352823500833539
Brusselle35842350083365795122148183199214249
G,385023500834357
et392423500833456
al.39972350083324760
Efficacy4074235008333506886118151183217
and430823500833169108
safety44332350083276079113135169
of461923500833757
dupilumab469323500833875114130145183240273312
in502223500831552
glucocorticoid-50912350083385491123160193230252276291323360376415437
-dependent30472450083216196135171209248283321343
severe34052450083266193128149183
asthma.36032450083325982120178210223
N3842245008344
Engl390224500833270109124
J4042245008324
Med.408124500835590129142
2018;378(26):2475-2485.423924500833468100131143178210243263296330348360395427459492514545577613647659
22.30472550085367288
Menzies-Gow315625500835490128157173207234255302340391
A,356825500834155
Corren36432550083407798120154192
J,385525500832537
Bourdin391225500833574112133171186224
A,415625500834155
et423125500833457
al.43082550083324760
Tezepelumab43882550083336393127166202217255313345384
in479225500831553
adults486525500833271109124146174
and505925500833270109
adolescents518825500833271109125160187219253291312340
with30472650083516689127
severe,31892650083266193128149183195
uncontrolled339926500833775108145183205226263279294329369
asthma.37832650083325881120177210223
N4021265008345
Engl408126500833371110125
J4221265008325
Med.426126500835489129142
2021.441826500833569102133142
23.30472750085367286
Wechsler314727500835790122159185199233254
ME,34152750083548799
Menzies-Gow352827500835589126155170204230250296334385
A,392627500834155
Brightling39952750083355671109146167182196233271
CE,42802750083407285
et437927500833355
al.44482750083324659
Evaluation45202750083336496111148179201215252290
of482427500833756
the48942750083215993
oral50012750083375890105
corticosteroid-51202750083316788112127158194220243276296333348386407
-sparing30472850083214784116137151188226
effect32842850083345372105136160
of345528500833755
tezepelumab35222850083215482115153188203239296327365
in389828500831552
adults396128500833270106120142168
with41412850083506586123
oral42752850083375890104
corticosteroid-dependent43912850083316787111125156192218240273293329343381403442476514548585623657694715
asthma51172850083325779116173204
(SOURCE):5333285008318499513917330472950083397189100
a3158295008331
randomised,32002950083205289126163219233258291329341
placebo-controlled,35522950083385383114146184221243276311348368388424439453486524536
phase409829500833976106132165
34274295008334
study.43192950083254784121152161
Lancet449029500833163100131163184
Respir46852950083356894131145165
Med.486129500835487125137
2022;10(7):650-660.50092950083346698131142171201219253271282316348381403439473507518
24.30473050085367085
Couillard314630500834076114128143157188209246
S,340730500833244
Jackson34663050083245587116144182220
DJ,37003050083466779
Pavord37933050083356697134155192
ID,40003050083156070
Wechsler408430500835890122159185200234254
ME.43533050083548799
Choosing446730500834077114152178193230268
the47503050083215993
Right48573050083365189126147
Biologic50183050083365088103140179194225
for52573050083195676
the53483050083225993
Right54563050083355030473150083387596
Patient31573150083356687102136173194
With33653150083587395132
Severe35113150083336799132153186
Asthma.37113150083416891128185217229
Chest.395431500834077112138160173
2025414131500833467100134
Feb;167(2):330-342.428931500833265104115145175207223256274285319352385408440475507519
25.30473250085367184
Kelsen31443250083356882107140177
SG,33343250083327587
Agache343432500834178109139176210
IO,36563250083156271
Soong374032500833370107144182
W,393432500835866
et401332500833455
al.40813250083314557
Astegolimab41513250083416789121159196211224281312349
(anti-ST2)45133250083194884105118139169202236253
efficacy4779325008334516986117149179211
and500332500833269106
safety51223250083265875109129162
in529732500831451
adults536032500833270106120141167
with30473350083506485121
severe31773350083265990122141174
asthma:33603350083325678114170200211
A3580335008341
randomized36303350083215288125161217231258290328
clinical3967335008331455894107137168182
trial.415933500832141548598109
J4278335008324
Allergy43123350083405467100120156186
Clin45083350083395366102
Immunol.461933500831571126162198234249260
202148883350083346697127
Sep;148(3):790-798.502533500833265102113141170204221253268278310341375397427458491503
26.30473450085367185
Wechsler314434500835790122159184199233253
ME,34093450083548799
Ruddy351934500833673111149180
MK,371134500835489103
Pavord38253450083356697134155192
ID,40293450083145969
et.41103450083345568
Efficacy4189345008333506885117149180213
and441334500833269108
Safety45323450083336583116138171
of471434500833856
Itepekimab47823450083143669107142172187244276314
in510734500831552
Patients51713450083356687101135172193220
with54033450083506587124
Moderate-to-Severe304735500835492131165186218239272295316352375406440472505526559
Asthma.36203550083416891128185217230
N3863355008345
Engl392235500833370108123
J4059355008324
Med.409735500835488127140
202142513550083346799130
Oct439535500834779102
28;385(18):1656-1668.45113550083346879113147180197228259276287316347380413436466497532566579
27.30473650085367078
Jackson31363650083245586115143180218
DJ,33653650083456677
Wechsler345436500835789120157183197231251
ME,37163650083548799
Jackson38263650083245586115143180218
DJ,40553650083456677
et414436500833355
al.42103650083324658
Twice-Yearly42793650083337893124157179210240271291306337
Depemokimab462736500834580118152209246276291348379417
in505536500831552
Severe51183650083326697131151184
Asthma53133650083416890127183215
with30473750083516587125
an318637500833169
Eosinophilic32693750083326995109146184223261275289304335
Phenotype.361837500833572106143181202235274309321
N3953375008344
Engl401137500833370108123
J4148375008324
Med.418637500835489128140
2024434037500833467100131
Dec448537500834580112
19;391(24):2337-2349.46113750083346375110142174188221252269280315349381412430461495529562572
ODBORNÝ38875790013353109164218272331378
GARANT:42855790013351105158212270315335
MUDr.38865950013370124177210232
Pavel4135595001335196139184209
Rutar43625950013352101136183216
Interní388660800131226694133160206226
oddělení,4129608001314286130170191231275295316
Nemocnice4462608001315191159201235280300333372
Na4851608001315291
Homolce,4959608001315193162204225258297317
Praha5293608001314471111156195
POŘADATEL:38876230013350106159214269320361406450476
Společnost3886640001314083125147186220265307339368
SOLEN,4272640001313989126165216236
s.4525640001313253
r.4592640001312745
o.,465064000131436382
ve4749640001313978
spolupráci4844640001313275118139182226253294327348
s38866530013132
Interním393565300131226694133160206226294
oddělením,4246653001314287131171192231276296364384
Nemocnice4647653001315291160202235280300333373
Na5037653001315191
Homolce5145653001315193161203224257297
PARTNEŘI:3407890012153114172228299353411441467
POČET4357420019689201295375459
KREDITŮ4357580019693184267376418500606
2109973000541246
Registrace16267410018485162248285346399450525592667
ZDARMA16267590018687191285372499598
TERMÍN25907420019684165256388430538
květen25907600013352107161197251312
202529257600013356111164220
až25907730013353100
duben27147730013362121183239300
202630377730013356111164218
dostupný25907860013362122165202262324385434
na30477860013361114
online.solen.cz25907990013763128159189253312340390453484543608637687740
ONLINE34243400227131262328430486617721
KURZ110243400227116245360472
OBSAH4485790014986158220296376
KURZU8465790014973154224293372
Management5615950014474120171217266312389435486519
MASLD10965950014475127172213267
–13805950014460
diagnostika1456595001445175121170221269304338361406453
jaterní1925595001442571104149180232255
brózy21965950014455105137185223268
v24805950014445
primární2542595001445183106183229261312336
péči2894595001445197134158
MUDr.5616090014169118166190205
Václav782609001414883115134170205
Šmíd,10046090014140108125167184
Ph.D.1204609001414486104152167
21.561627001444993113
století:690627001443771118142188221244267
nastal973627001445298134168214238
čas1228627001443784120
pro1365627001445182131
optimální1512627001444999132155232278302352376
suplementaci1904627001443787137161207284330380413460496520
železem2440627001444085109155194239316
doc.561642001414485118138
MUDr.7156420014169118166190205
Jiří9366420014129477189
Slíva,104164200141415975111149166
Ph.D.,1223642001414486104152167184
MBA14236420014169112160
Broncho-Vaxom561660001445486134185221272320352399443487533610
v11886600014445
prevenci1249660001445183129172217268304328
opakovaných1593660001445099146191237280326376418453505
respiračních2114660001443379115164188219266301353376412463
infekcí2594660001442475105151196231255
MUDr.5616740014169118166190205
Mojmír7826740014169110127195212236
Račanský1034674001414583115154196226262301
Přednáška56168800141426699139181221249284323
sponzorovaná900688001413170109152183220246283318357399439
společností1354688001413271110127162193234272301324341
417106880014143
Life176968800141375374109
Pharma1893688001414383123148212253
CZ,216168800141418197
s.r.o.22746880014131507588126143
Cestovní561706001444691127161208250302325
medicína9037060014478124174197233257308354
pro1274706001445182131
praxi1421706001445183129173196
–16347060014160
MUDr.17107060014169118166191205
Milan1931706001416986104141183
Trojánek,213070600141405999117154196234270289
Ph.D.2435706001414486104152167
15188411001202548
20254608501005772635197691023
Medicína34047700415285469678780933103712401426
pro34051300415201340539
praxi95751300415202340522709811