1297
HLAVNÍ506722001005185134178232252
TÉMA533422001003981147194
ANCA-asociované362433001004295135180205239268307338353392427463500536
vaskulitidy41763300100357099134172187202229245284320
–4512330010038
diagnostické45663300100385387126163202232259275306340374
a4956330010034
léčebné50063300100155081116154192227
možnosti524933001005998129167206235263279
|5584220010018
413564222001004166101
/35898040010732
Vnitř3666804001074592111139166
Lék.3851804001074184122140
2025;71(7):408-4134011804001074487128172185226267286329354368411457502530577615652
/47088040010732
VNITŘNÍ48058040010746106127172221280301
LÉKAŘSTVÍ5128804001074084130188235279325377399
www.casopisvnitrnilekarstvi.cz42580400107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
cílenou4256200107405979123172220268
na71162001074889
IL-5,8186200107195977120134
kterou97062001073869111138185233
se122162001073478
pak131762001075091129
doporučuje146462001074997147197224272312360379423
využít190562001074084132169188216
také213962001072869107150
v2307620010741
léčbě236662001071963104153198
relabující25826200107277089129179227246265305323
a425760010741
refrakterní4867600107266993121162200231273300349367
EGPA.87376001074298143190208
Závěr4251010013862123184242288
ANCA-asociované5651180010753110162216242282315363404422470510551598642
vaskulitidy1232118001074182115152200219236264282331371
jsou1628118001071952100148
vzácná1800118001074180122162210250
onemocnění,2075118001074897140214262303351395442460475
na2575118001074989
něž2689118001074892129
je2842118001072063
vhodné425132001074189136185233276
pomýšlet723132001075098171209242260303330
zejména107613200107367896168212259299
u13971320010748
pacientů1467132001075091131148191238264311
s18011320010733
celkovými1857132001074081100137183222265338356
nespecifickými2236132001074891124172216257274297316356392434508526
příznaky,278413200107507694425146001073683122158199209
nejasnou648146001074891108146178224271317
elevací979146001074361103142182221238
zánětlivých1231146001073676123165191209225265306344390
parametrů1635146001075089114154225268294319366
a20151460010740
známkami2069146001073683122193230270342359
postižení2442146001074996128156173208249295312
více276814600107405897137
orgánů.304762001074773119158204250263
Typické332462001074274123141179216257
jsou35956200107195097143
chronické375262001074086111156203220258295336
rhinosinusitidy,41026200107267390136183215231278323355371398415462501511
nejasné462762001074890108146178224266
plicní49076200107496885123169187
noduly510862001074794142188205244
či536662001073956
infiltráty,5436620010719653047760010723415884109149174214224
krvácení328576001073764105145183224270286
do358576001074894
plic36937600107496783121
a3828760010740
rychle388276001072667104150167209
progredující410576001074974119166191232280325342359397414
glomerulonefritida.453276001074865111183225250296313359405447469495513539556603641656
Diagnóza520276001075774113160206252285325
může3047900010774121157199
být327190001075089120
potvrzena341590001075099126169196234276324364
pozitivitou380490001075099133152180198238257285331379
ANCA4207900010753110161215
protilátek444790001075076123150168186226252294332
a/nebo480490001074174119163212261
provedením509090001075076123162205255298346364437
biopsie.3047104001074967114162194211253267
V33281040010746
léčbě3388104001071961101148192
se3594104001073376
uplatňuje3684104001074895114153179225271289331
kombinovaná4029104001073884156204222268315354394440479
imunosupresivní4523104001071890136182229261307355380422454471510558575
a51121040010741
biologická5167104001074967114132179227244283320360
terapie304711800107276892132179197239
(kortikosteroidy,3299118001072460105131160177213258289316357382426444491529539
cyklofosfamid,3852118001073979116135181203249280304344415432478492
rituximab),435811800107264470116153171242280328348360
nutná4731118001074893119166204
je4949118001071961
individualizace5023118001071965112129168186232278316334350385425464504
léčebného3047132001071964105147197246290339388
postupu.34601320010751100134163211261309325
Pro3811132001074671118
vzácnost3955132001074180123163212260294323
onemocnění4303132001074998142217266307355400448466
by4795132001075090
pacienti4910132001075192133151195244271289
měli52251320010775119138156
být5406132001075190122
sledování304714600107335093141187226266312329
v33901460010740
expertních3444146001074381129173197227273290329375
centrech3833146001074080127152177218258304
s41511460010733
dostupností4198146001074895127154200248295341373401418
multidisciplinárního46301460010773119136162180227244275314331379397414460499524571588636682
týmu.5326146001072869141187201
PROHLÁŠENÍ48517600974387144199239292335376430452
AUTORŮ:954176009749101143200245299316
Prohlášení128617500984573119166187229263305352373
o1674175009845
původnosti:173517500984693134179227274320354383404423
Publikace217417600954082127144161195233269308
byla24981760095447997133
zpracována264717600953378102139176218254291334371
s3034176009529
využitím307917600953775119152169195212277
uvedené337217600954380119163203246286
literatury3674176009517335997121158183226249288
a3978176009536
nebyla403017600954383127163181217
publikována426317600954487132150166200243279316359396
ani46751760095367996
zaslána478717600953270100117153197233
k5036176009534
recenznímu50861760095236299137180213257274340382
řízení4851880095244174112156172
do67618800954387
jiného7811880095173477117160203
média.1003188009565105150167203218
Střet12391870098426998141170
zájmů:142618700983679100169215234
ZH167918800954393
–1791188009540
platba18491880095446299123168205
za207218800953371
konzultace/přednášky:216118800953476120153196214239276312350380422447485530573609639673712727
CSL290618800954684119
Vifor,30441880095405981123148158
Astra322118800954778104128166
Zeneca,340518800954381125164201238253
GSK.367618800955088127144
VT383818800954183
–3940188009540
CSL399818800954684119
Vifor,41361880095405980123147158
AstraZeneca,431318800954778104128166209247290330367404419
Boehringer475018800954084124168191209252296335359
Ingelheim,512818800951760104143161204243260326340
Novartis,48520000955195131168192220237266281
Otsuka,78320000955480112154188226240
Stada,10412000095376198142179193
Travere,12522000095375693129168192230244
Vera.151320000954178102139154
Financování:168419900984161108149195232277318359406427446
Žádné.214720000954380125168207221
Poděkování:238519900984590137180221266307348395416435
N/A.283720000955180122139
Registrace299419900984688135156190219248290326368
v3378199009841
databázích:343619900984687116158205247284306342389408
N/A.386120000955180122139
Projednání401719900984573119141183231278319365387
etickou44201990098417192128170214261
komisí:469719900984186155176210231250
N/A.496520000955180122139
LITERATURA426225001234978134189250318368438498567
1.42524200853648
Jennette4912420083245997135170193217251
JC,7602420083246578
Falk8562420083326277107
RJ,9812420083356274
Bacon107324200833669101138176
PA,12672420083367387
et137224200833456
al.14472420083314760
2012152524200833468100130
revised16732420083215587103129164203
International18942420083155375108130168201222238276314346362
Chapel227424200834078110149185200
Hill2492242008344607590
Consensus260024200834077115142177215241278305
Conference42525200834077115134169190224262294328
Nomenclature76825200834583142177215247262294316354375409
of119325200833756
Vasculitides.12642520083366794126164179194217232271306332346
Arthritis16252520083416387126147162185200226
Rheum.186625200833674109147205218
2013;65(1):1-11.209925200833469100130142177211229261275287317335366394403
2.42526200853651
Redondo-Rodriguez49026200833570110148186225263286323361401422438476514549578
R,108126200833549
Mena-Vázquez114326200835489127160182218249278316354389418
N,157426200834457
Cabezas-Lucena164426200834073112147177210237258291327360393431463
AM,212026200834197110
et224326200833456
al.23122620083324760
Systematic23852620083326289112145203235257272304
Review270226200833570102118153204
and42527200833270109
Metaanalysis54827200835489112144177215247262294321336362
of92427200833756
Worldwide99427200835894116132170222237276311
Incidence13192720083155385100139174212244278
and161027200833270109
Prevalence17332720083355690122155171205244276309
of205627200833857
Antineutrophil212727200834179100116154189226249270308347386401416
Cytoplasmic25572720083406792129169185217243301316348
Antibody42528200834179101116155194233265
(ANCA)70628200831860105146188207
Associated9292820083416895133166181213235268308
Vasculitis.12522820083366794126164179194217232258272
J1539282008324
Clin15782820083405570108
Med.170228200835489129142
2022;11(9):2573.185928200833468101136148178206221254272284319354387421434
3.42529200853650
Rathmann4862920083356788125181212249286
J,78329200832435
Segelmark83029200833266104138153209240261290
M,113129200835467
Englund120929200833369107121158195233
M,145329200835466
et153129200833355
al.15972920083314658
Stable16662920083325284122137171
incidence1848292008315518297134168205236269
but21282920083387597
increase22362920083155283103136167192226
in247329200831552
prevalence25362920083385992123155169203240271304
of285129200833755
ANCA-associated42530200834084124165185216241267303335349379400432470
vasculitis9063020083316388119156170184205219244
in116130200831451
southern12233020083256299120157191211248
Sweden:148230200833280113151185221232
a1725302008332
23-year17683020083336787118151181201
study.19803020083264885122153162
RMD215330200833588133
Open.229730200834684119155167
2023;9:e002949.24753020083346798132142176188221255290322354389421430
4.42531200853651
Almaani49531200834156114146179217232
S,74531200833346
Fussner8093120083326995122159194216
LA,10433120083317589
Brodsky11503120083365794134160190224
S,139231200833346
et145631200833456
al.15313120083324760
ANCA-Associated160931200834186127170192233261287326358373405427461500
Vasculitis:21283120083356793125163179194216231257270
An241631200834179
Update.251431200834483122155176210222
J2755312008324
Clin27973120083405570108
Med.42532200835490129142
2021;10(7):1446.58332200833468101132140170202221256276288317348385421435
5.42533200853548
Sánchez4833320083326399129165198225
Álamo7183320083405484139175
B,90333200833546
Moi95833200835490104
L,107133200833143
Bajema11233320083356680112168198
I,133133200831425
et136633200833354
al.14293320083314556
Long-term149533200833066102139159180211231287
outcomes17913320083377393122157213246271
and207133200833167104
prognostic21853320083385793130166202227248261291
factors24863320083184979101136156181
for26763320083195474
survival275933200832661801131274253420083326377
of51234200833856
patients5783420083397090104138174194221
with8093420083516586123
ANCA-associated94234200834185124165186216242267304335349379400432470
vasculitis.14223420083326389119156170183204218243255
Nephrol168734200834579117154173209224
Dial19213420083456090104
Transplant.20353420083334980117142179194225261281293
2023;38(7):1655-1665.23393420083346798131141175208226259277288316346378409430459489523556566
6.42535200853652
Robson49635200833574113140178217
J,73235200832436
Doll78735200834584100115
H,92135200834457
Suppiah99735200833269109148164196234
R,125035200833549
Flossmann13183520083324785112138196228266304
O,164135200834759
et171835200833457
al.17943520083314760
Damage187335200834577135167206241
in213335200831553
the22053520083216095
anca-associated231935200833169102134157189216242281313328360382416455
vasculitides:27933520083326591425362008331698499122137176211238250
long-term6923620083155392131153175209230289
data9983620083387092125
from11403620083184178136
the12933620083226095
European14053620083336990128167203235273
vasculitis16953620083316491123161176191214229255
study19673620083265087127158
group21433620083385996134173
(EUVAS)23333620083195295132171205224
therapeutic25743620083216095116149188223261284299331
trials.425372008322435991106132146
Ann58637200834179117
Rheum71837200833674109147205
Dis.9383720083456187101
2015;74(1):177-84.105437200833468100130141174204224255270282311341375394430466479
7.42538200853645
Sanchez-Alamo48638200833265103136174209238260301317349407445
B,94738200833548
Moi101138200835493108
L,113538200833145
Bajema11963820083356883118176208
I,142038200831528
et146438200833456
al.15363820083324760
Long-term161238200833169107146168191224246304
outcome19323820083377598129166224259
of220738200833756
kidney22793820083304685123158190
function24853820083185795127151166204243
in274338200831553
patients2812382008339724253920083223772110131159
with5993920083516689127
ANCA-associated74139200834186127170192224250277315348363395417450490
vasculitis.12463920083326591124161177192214230256269
Nephrol153139200834479118157178215231
Dial17783920083456092108
Transplant.19013920083335083121147186202234272294307
2024;39(9):1483-1493.222439200833468101132144179213232264282294324355391425447478509542575587
8.42540200853551
Ooi4884020083468499
LJ,5994020083315869
Hollick6814020083438196110125156185
RJ,8794020083356172
Brix9634020083355671101
SR.10774020083326680
Challenges116940200833977108123137172209247281307
and148840200833269107
advances160740200833270102134171203235262
in188140200831451
the19454020083215892
management205040200835688125156195229286320357378
of244040200833756
antineutrophil25084020083316889104141175212234255291330368382397
cytoplasmic4254120083316489125164180212238295310341
antibody7794120083326990105144183222253
vasculitis10454120083316490122159174189211226252
in131041200831452
2025.137441200833468100135147
Curr15334120083407697118
Opin166441200834786101139
Nephrol181541200834579118156177214229
Hypertens.205741200834475115150171195229266292306
2025;34(5):375-380.237541200833468100135145180215234267285297332363396418450484518531
9.42542200853650
Gopaluni49542200834483123156171209247262
S,77842200833245
Flossmann8444220083324785112139197229267306
O,117042200834759
Little1249422008332477094110145
MA,141442200835597111
et154642200833456
al.16234220083324760
Effect17044220083335271105138162
of188742200833757
Disease19644220083466188123155182217
Activity22014220083417397113145161184218
at243942200833254
Three25144220083327293127163
and269742200833270110
Six28274220083334879
Months42543200835493131153191217
After6574320083416085119140
Diagnosis8124320083456092131169208234249275
on110243200833776
Long-Term119243200833269108147169199230251309
Outcomes151643200834785108139176234269296
in182743200831452
Antineutrophil189443200834179100116154189226249270308347386401416
Cytoplasmic23254320083406792129169185217243301316348
Antibody-Associated2688432008341791001161551944254420083387092133161188226259274306328361401
Vasculitis.8414420083366794126164179194216232258271
Arthritis11284420083416287125146161184199225
Rheumatol.136944200833573108146204236258295311324
2019;71(5):784-791.170844200833468100130143176208224257275287321354390413445478510519
10.4254520085367186
Hollick53345200834584100116131164195
RJ,7494520083366376
James84645200832457116152179
WRG,104745200835895140154
Nicoll12224520083466194132148164
A,140745200834156
et148445200833457
al.15624520083334962
Identifying16454520083155590129152167187222239277317
key19834520083306597
health210145200833974107123146185
system23074520083266087111145205
components253345200833169128168208247283322344372
associated4254620083325885123156171203225258298
with7394620083516689127
improved88346200831472111133170202236276
outcomes11754620083377598129166224259286
to147746200832259
inform15524620083155371109131189
the17574620083226095
re-configuration18694620083205477111148187204221260298319352373389427465
of235146200833756
services24234620083276283118133165199226
for26654620083185678
adults27594620083327110812442547200832249
with4924720083516689127
rare6374720083215475109
autoimmune7644720083316992129144202260297335370
rheumatic11524720083215994132190222244259291
diseases:14614720083385379114146173208235247
a1726472008332
mixed-methods177647200835772103137177199258293315353392431457
study.22514720083265088127159169
Lancet243847200833164102135168191
Rheumatol.264647200833674109147205237425482008322597487
2024;6(6):e361-e373.52848200833468101133145180199233251263297331366396415451486518552564
11.4254920085366678
Bossuyt51949200833574101127164196221
X,75549200833852
Cohen82249200834077115150188
Tervaert10264920083326384119152187208233
JW,12744920083248292
Arimura13814920083416278136173194227
Y,162449200833543
et168249200833456
al.17544920083314760
Position18294920083357298113136151189227
paper:207249200833871110146167181
Revised226849200833570103118144179219
2017250249200833468100130
international2647492008314527410812916720022123742550200833776108123
consensus56650200833168107133168206233270296
on88050200833776
testing9735020083225683106121159198
of118950200833756
ANCAs126350200834186127170198
in147950200831452
granulomatosis15495020083385992130168183221279312333370397412438
with20055020083506688127
polyangiitis21495020083397894126159197236251266288304330
and249750200833169108
microscopic2623502008358731051261631902222594255120083395486
polyangiitis.5265120083397894126159197236251266288304330343
Nat8855120083447798
Rev99951200833570102
Rheumatol.111751200833573108146204236258295311324
2017;13(11):683-692.145651200833468100130139170199218249277291303339374408430467501534547
12.4255220085366884
Hunter52252200834482120141175196
RW,73152200833694104
Welsh84852200835790106132170
N,103152200834457
Farrah11015220083336283105138176
TE,12905220083336780
et138352200833457
al.14535220083314760
ANCA152652200834186127169
associated17095220083315884123155171203224258298
vasculitis.20205220083316491123161176191214229255269
BMJ.230252200833590116128
2020;369:m1070.244352200833569101136148183218252265323353384417450462
13.4255320085356781
Chevet51853200833976110142175197
B,72753200833447
Cornec7865320083397596133168199
D,99753200834555
Casal10645320083407297130144
Moura122153200835391128148180
M,141353200835467
et149253200833355
al.15595320083314658
Diagnosing16295320083456091129166203229244280319
and196053200833168106
treating20785320083214275106127142179217
ANCA-associated230753200834084124166187218244270307339353384405438477
vasculitis:27965320083316389425542008331678296118133158170
an60754200833168
updated68754200833775113145166198237
review9365420083205385100133183
for11315420083185576
clinical1219542008330455996111142174188
practice.14195420083385991122146160191224236
Rheumatology166754200833472106142199230251287302340378409
(Oxford).20885420083186394115151172209228238
2023;62(5):1787-1803.23385420083346799133144178211227260278289318346379411429459489523555567
14.4255520085366984
McAdoo52255200835487129168206245
SP,7805520083326771
Tanna8645520083336199137169
A,104655200834155
Hrušková111455200834465104130160197229262
Z,138955200833851
et145355200833456
al.15225520083324760
Patients15955520083356789104139177198226
double-seropositive183455200833876114153169204227254289310347387426452467489505537571
for24185520083195678
ANCA250955200834186127170
and269255200833169108
anti-GBM2813552008332704255620083223759105141195
antibodies6335620083327091106145184223238272299
have94556200833769101135
varied10935620083316485100135174
renal12805620083205492124139
survival,14325620083266384119134167199214227
frequency16715620083194175114151186224256289
of197356200833756
relapse,20425620083205470102140167202214
and226856200833270109
outcomes23895620083387598128165223258284
compared2686562008331681261651984255720083215594
to53557200832158
single-seropositive6085720083274179118134168192219254275312352390417432454470502537
patients.11605720083397293109143181203231244
Kidney14205720083345190128163194
Int.1630572008314527487
2017;92(3):693-702.173257200833569100130140175208226259276288324358390412444477510522
15.4255820085366883
McCarthy52858200835487128161182207245275
E,82458200833245
Mustafa89058200835492118141174193227
M,113758200835468
Watts122558200835789111135163
M.140858200835468
ANCA-negative149758200834186127169191230265304336358373406440
Granulomatosis19585820083436598136173189227285318339376403418444
with24225820083516689127
Polyangiitis:25695820083357288120153191230245260282298324336
A425592008341
Difficult481592008346618098115147185201223
Diagnosis.7195920083466193132170208235250276290
Eur10245920083336990
J1130592008324
Case11695920083407399134
Rep131959200833570109
Intern14445920083145274108129168
Med.162759200835489129142
2017;4(8):000625.178459200833569100130140174194227245257293329365401434469481
16.4256020085366985
Kidney5316020083355190128163195
Disease:7466020083456187122154180215228
Improving99460200831573112134171203219256295
Global13106020083446098137170186
Outcomes151660200834785108139176234269296
(KDIGO)183260200831954101116161209227
ANCA207960200834186127170
Vasculitis22696020083366793126163179194216231258
Work254760200835794115146
Group.271360200834466103141180193
KDIGO4256120083358298142190
202463161200833468101133
Clinical7806120083405570108123155188203
Practice9996120083355689121145160192226
Guideline12416120083448297136171186201239274
for15316120083195678
the16256120083216095
Management173661200835487125157196231289324362384
of213661200833756
Antineutrophil220861200834179101116154189227249271308348386401416
Cytoplasmic2640612008340689313016918521824442562200835772104
Antibody54562200834179100116155194233265
(ANCA)-Associated82562200831960105146189208231272300326365397412444466500539
Vasculitis.13806220083356793125163178193216231257271
Kidney16666220083355190128163195
Int.1876622008315537488
2024;105(3S):S71-S116.197962200833468101133145175206241258292323342354388421454473504535562594607
17.4256320085366776
Hellmich5146320083447995110167182214252
B,77963200833548
Sanchez-Alamo84063200833265103135173208237259300315348405444
B,129663200833648
Schirmer135763200833365103118139197232253
JH,16236320083246982
et171863200833456
al.17876320083324760
EULAR186063200833276107151186
recommendations20596320083215587124182240275313352384406421459497524
for25966320083185677
the26866320083226095
management27946320083578942564200833870109144202237275296
of73764200833756
ANCA-associated80964200834086127169191223250276314347362394416450489
vasculitis:13146420083316491123161176191213229255267
2022159764200833468101135
update.174864200833776116148170204216
Ann197964200834179117
Rheum211164200833674109147205
Dis.23316420083456187101
2024;83(1):30-47.244764200833468101133145180214232264278290325360384420452458
18.4256520085366985
Robson52865200833574113140178217
JC,7626520083246578
Grayson8576520083446598129156194233
PC,11076520083357689
Ponte121365200833572110132166
C,139665200834053
et146665200833456
al.15396520083324861
2022161765200833468101136
American177065200834199134155171203235274
College20616520083407793108142182217
of229565200833757
Rheumatology/European2369652008335741091462042372582953113493894214444785154256620083215897133165203
Alliance642662008340567186118156188222
of87766200833857
Associations9486620083416895133166181213235250288326353
for13146620083195678
Rheumatology140666200833573108146204236258295311349388421
classification18406620083314779105132147165181214246268283321360
criteria2213662008332536991125146162194
for24206620083195678
granulomatosis251166200833860931311681842222803123343714256720083264167
with5076720083516689127
polyangiitis.6496720083397894126159197236251266288304330343
Ann100867200834179117
Rheum114067200833574109147204
Dis.13606720083456187100
2022;81(3):315-320.147667200833468101135148183215230264281293328359389411443476510522
19.4256820085366882
Suppiah52068200833270109148164196234
R,76668200833650
Robson82968200833573113139177216
JC,10586820083246577
Grayson11486820083446598129156194233
PC,13936820083367689
et149568200833456
al.15646820083324760
2022163768200833468100135
American178568200834199134155170202235273
College20716820083407793108142182217
of230068200833857
Rheumatology/European2370682008335731081462042362582943103483884204434775134256920083215897133165203
Alliance647692008341567186118156188222
of88869200833757
Associations9646920083406895133166181213235250288326353
for13366920083185677
Rheumatology143269200833574109147204237259295311350389421
classification18726920083314779105132147164181213246268283321360
criteria2251692008331526890124145161193
for24636920083185677
microscopic255969200835873105126163190222259299314346
polyangiitis.4257020083397793125158196235250265288303329343
Ann78370200834179117
Rheum91670200833573108146204
Dis.11357020083466187101
2022;81(3):321-326.125170200833468101136148184215231264281293328361392411443476510523
20.4257120085367287
Grayson5307120083446598129156194233
PC,7817120083357588
Ponte88771200833572111132166
C,107171200834053
Suppiah114271200833269109148164196234
R,139471200833549
et146171200833456
al.15357120083324760
2022161371200833468101136
American176771200834199134155171203236274
College20597120083397692107142182217
of229471200833756
Rheumatology/European2368712008335741091472042372592963113503894214454785154257220083215897133165203
Alliance645722008341577287119157189223
of88572200833757
Associations9597220083416995134166181213235250288327353
for13297220083195678
Rheumatology142472200833674109147205237259296312350389421
Classification18637220083405587114140155173190222255276292330368
Criteria2249722008339607698132153169201
for24677220083195678
Eosinophilic25627220083337097112150188228266281296311343
Granulomatosis4257320083446598136174189227286318340377403418444
with8857320083506688126
Polyangiitis.10277320083357287119152190229244259282297323337
Ann137973200834179117
Rheum151273200833573108146204
Dis.17317320083466187101
2022;81(3):309-314.184773200833468101136148184216231264281293328363398422454485516529
21.4257420085367082
Lyons5227420083316097136162
PA,6997420083357387
Rayner8017420083356899137172194
TF,10107420083326672
Trivedi1097742008333506598132172187
S,129974200833245
et135974200833456
al.14307420083324860
Genetically150574200834480118153175190222255270286317
distinct18377420083385480103118156188212
subsets206474200832664103129164187214
within22937420083516789127142180
ANCA-associated2488742008341861271701912242502773153483633954257520083225595
vasculitis.5357520083326591124161177192214229256269
N819752008345
Engl87975200833371110125
J1019752008325
Med.105975200835489129142
2012;367(3):214-23.121675200833569101130143178212245261295312324359391422445476511523
22.4257620085367288
Hilhorst5347620083445975112151172200223
M,77776200835568
van86676200833164102
Paassen9897620083356799126152187226
P,123576200833540
Tervaert12957620083336385119152187209233
JW;15497620083248294
Limburg166376200833247105144182204242
Renal192576200833671109141157
Registry.210276200833570110125151174196230240
Proteinase23627620083365694116149164202235261296
3-ANCA26797620083345697142183226
Vasculitis4257720083356693124162177192214229255
versus6927720083326687114150176
Myeloperoxidase-ANCA88177200835485119135173212247268305335350388420447481504545590630673
Vasculitis.15667720083366793125162177192214229255268
J1847772008324
Am188477200834098
Soc199577200833270102
Nephrol.211077200834479118156177214229242
2015;26(10):2314-27.23657720083346799128139174207226257288306318353387418448471502534540
23.30472420085367287
Jayne31522420083245687126161
D,333024200834556
Rasmussen34032420083356895152190216243278316
N,373624200834558
Andrassy381124200834079118139172198225258
K,408624200833449
et415224200833456
al.42252420083324760
A4302242008341
randomized43602420083215492131169228243272306345
trial4722242008322435991106
of484524200833857
maintenance491924200835790105143164198236268306339372
therapy53082420083226095116149188220
for30472520083185678
vasculitis31442520083316491123161176191213229255
associated34182520083325885123156171203225258298
with37352520083516689127
antineutrophil38812520083327091106144179217240261298338376391407
cytoplasmic43072520083316489126166182214240298313345
autoantibodies.46712520083327092129162200222237276315354370404431445
N5135252008344
Engl519825200833371110125
J5342252008324
Med.538525200835590129143
2003;349(1):36-44.304726200833468104138149184219252272303318330365399423459496509
24.30472720085367186
de314827200833873
Groot323527200834466103141163
K,341327200833549
Harper34762720083457798138173195
L,368527200833145
Jayne37442720083245687126161
DR,39192720083468296
et402927200833456
al.41002720083314760
Pulse41742720083357288114149
versus43372720083326687114152178
daily45292720083387186101133
oral46762720083375992107
cyclophosphamide47972720083326597112150190228266293332371403461476515550
for53612720083185677
induction545327200831452304728200833876108132147185224
of328528200833857
remission335728200832155113128154180195233272
in364328200831553
antineutrophil37112820083327091106144179217240261298338376391407
cytoplasmic41332820083316489126166182214240298313345
antibody-associated44932820083327091106146184224256278310337363402434449481503537576
vasculitis:50842820083326591124161177192214229255268
a5367282008332
randomized54132820083215492304729200833876135150179213252
trial.3315292008321435890106119
Ann344929200834179117
Intern35812920083155375108130168
Med.376529200835489129142
2009;150(10):670-80.392229200833468105140153183213247266298329348360395428461485521556569
25.30473020085367287
Flossmann31473020083324785112138196228266304
O,346430200834758
Berden35353020083357092130164203
A,375130200834055
de381930200833872
Groot390430200834466103141163
K,408030200833550
et414330200833456
al.42123020083324760
Long-term428530200833169107146168191224245304
patient46023020083387193108143181202
survival48173020083276485120135168201216
in504630200831552
ANCA-associated51113020083418612717019122425027731534736239430473120083225595
vasculitis.31573120083326591124161177192214229256269
Ann344131200834180118
Rheum357431200833574109146204
Dis.37943120083456086100
2011;70(3):488-94.390931200833569100128136169202222255273284319355390413448484496
26.30473220085367187
van315132200833265103
Daalen327132200834577109125160198
EE,34863220083326578
Rizzo35813220083355180111148
R,374632200833650
Kronbichler38133220083345794133172187219257273308329
A,415932200834155
et423132200833456
al.43043220083324760
Effect43813220083335270105138162
of456032200833756
rituximab4633322008321365997128144201234273
on492332200833775
malignancy501532200835890105120159197230268300333
risk5365322008321366392
in547432200831553
patients30473320083397293109143181203231
with32933320083516689127
ANCA-associated343533200834186127170191224250277315348363395416450490
vasculitis.39403320083326591123161177192214229255269
Ann422433200834179117
Rheum435733200833573108146204
Dis.45763320083466187101
2017;76(6):1064-1069.469233200833468100130139172204223256275286316348383420443474505541575586
27.30473420085367180
Stone31463420083325491129164
JH,33293420083256982
Merkel343134200835489110141175191
PA,36413420083357387
Spiera37473420083337187122143176
R,394234200833650
et401134200833456
al.40873420083314760
Rituximab41663420083355173111143158216248287
versus44733420083316687114151178
cyclophosphamide46703420083316596112150189228266293332370403460476514549
for52393420083185677
ANCA-533634200834186127169191
-associated30473520083215380106145177192224246280319
vasculitis.33823520083316491123161176191214229255269
N3666352008345
Engl372635200833270109125
J3866352008324
Med.390535200835590129143
2010;363(3):221-32.406335200833468100131144179214248266299316328363398430448481513526
28.30473620085367288
Jones315236200832462101136163
RB,33323620083357284
Tervaert34333620083336485120153187209233
JW,36833620083258393
Hauser379336200834476114140175196
T,400636200833342
et406536200833456
a.413836200833245
Rituximab42013620083355073111142158215248287
versus45053620083326687114152178
cyclophosphamide47003620083316596112150189228266293332370403460476514549
in526636200831553
ANCA-533636200834186127170191
-associated30473720083215380106145177192224246280319
renal33823720083205492125140
vasculitis.35383720083316491123161176191213229255268
N3822372008344
Engl388237200833270109124
J4022372008324
Med.406137200835590129142
2010;363(3):211-20.421937200833468100131144179214247265299316328363395422441472506519
29.30473820085367285
Guillevin31473820083448297112127162194210248
L,340938200833145
Pagnoux346838200833567106144182220252
C,373438200834053
Karras38013820083346889111144171
A,398638200834155
et405538200833456
al.41253820083324760
Rituximab41993820083355173111143158216248287
versus45003820083326687115152178
azathioprine46923820083326295117155170208248269285323358
for50643820083185677
maintenance515538200835890105143165198236269307339373
in304739200831553
ANCA-associated311539200834186127170191223250276315347362394416450490
vasculitis.36203920083316491123161176191214229255269
N3904392008345
Engl396439200833370109125
J4104392008324
Med.414439200835489129142
2014;371(19):1771-80.430139200833468100131143178210243258289319337349379409443476494530565578
30.30474020085367287
Smith314740200833290105127165
RM,332540200833691104
Jones344240200832563101136163
RB,36184020083357284
Specks371540200833371107140170198
U,392640200834455
et399440200833456
al.40634020083324760
Rituximab41364020083355173111142158216248287
versus44364020083326687114151178
azathioprine46274020083316194116154169207246268284321356
for49964020083195678
maintenance508740200835789104142164197235268306338371
of547140200833757
remission304741200832154112127153179194232270
for33304120083185577
patients34194120083397293108143181202229
with36614120083516688126
ANCA-associated380041200834186126169190222248275313345360392413447486
vasculitis42994120083316490122160175190212227253
and456541200833269108
relapsing46864120083215470102141167182219258
disease:49574120083385379114145172206219
an518841200833270
international52714120083145273107128166198220235304742200833776108123
randomised31864220083205391130169227242268303343
controlled354442200833168107128150187203218253292
trial.3851422008322445991107119
Ann398642200834179117
Rheum411842200833674109147205
Dis.43384220083456187100
2023;82(7):937-944.445442200833468101136147182216233268287299334367399418453489526538
31.30474320085366981
Podestà314043200833571110145171194227
MA,337943200835596110
Mescia350243200835488115147162193
F,370843200833238
Ricchiuto37594320083355082112150165202224260
A,403243200834155
et409943200833456
al.41684320083314659
Predictors42404320083355589128143174198235256283
of453643200833756
hypogammaglobulinemia460443200833868108146185217274332364402418455494532547562600634692706738
in535543200831452
ANCA-associated541943200834186304744200834082104136163189227260275307329362402
vasculitis34624420083316491123161176191213229255
after37304420083315075109130
a3873442008332
rituximab-based3918442008321365996128143201233272296336368395430469
induction:44004420083155392129161185201239277289
a4702442008332
multicentre474744200835795110132148179213251273294328
study.50884420083264987126158168
Rheumatology52694420083357410914620423630474520083225974113152184
(Oxford).32474520083186496117155176215234245
2023;62(8):2850-2854.350745200833569102136148184217234268286298333367401435459490523557593605
32.30474620085367186
McAdoo315146200835487130168206245
SP,34134620083326771
Pepper350146200833569108148183205
RJ,37224620083366375
Prendecki38144620083355589128167201234264281
M,411146200835568
et419646200833456
al.42694620083324860
Long-Term434646200833269107147169199230251309
Follow-Up46724620083327086101139190212258297
of498646200833756
a5059462008332
Glucocorticoid51084620083435997129166199235257282297329366381420
Minimizing304747200835470108123181196225240278317
Regimen338347200833570110125183218256
for36574720083185678
the37534720083226095
Treatment38664720083335084116138196231269291
of417547200833757
Severe425047200833368100134156190
Antineutrophil445847200834179101116154189227249271308347386401416
Cytoplasmic48934720083406792129169185217243301316348
Autoantibody-Associated526047200834178100137170208230245304748200833977117149171212240267305338353385406440480
Vasculitis.35424820083366793126164179194216232258271
Kidney38294820083345190128163194
Int40394820083145274
Rep.412848200833671110122
2025;10(6):1874-1885.426648200833468101136146176208228261279291321352385415438469500535569581
33.30474920085367185
Walsh314549200835788104129167
M,332549200835467
Merkel340549200835489110141175190
PA,36084920083357286
Peh370749200833568106
CA,38264920083408296
et393549200833456
al.40034920083324760
Plasma40764920083355082108165197
Exchange42864920083336596134166204242277
and457649200833269108
Glucocorticoids46974920083435997128165198234256280295327364379418444
in515449200831452
Severe52194920083326799133154188
ANCA-Associated542049200834085304750200834083104145173200238271286318340373413
Vasculitis.34755020083366794126164179194216232258271
N3762502008344
Engl382250200833270109124
J3962502008324
Med.400150200835590129142
2020;382(7):622-631.415950200833468101135148183217251268303322334370403438458495529560569
34.30475120085367388
Jayne31525120083245687126161
DRW,332951200834582140149
Merkel349451200835590111142176192
PA,37025120083357286
Schall380451200833365103135151166
TJ,39865120083335466
et406851200833456
al.41405120083324760
Avacopan421651200834172105137174214247285
for45175120083185677
the46105120083226095
Treatment47215120083335084116138196231269290
of502851200833756
ANCA-Associated51005120083418612717019123326128732535837340530475220083225595
Vasculitis.31575220083366794126164179194216232258271
N3444522008344
Engl350452200833270109124
J3644522008324
Med.368352200835590129142
2021;384(7):599-609.384152200833468101132141176210246266300320332367399435458496531566577
35.30475320085367186
Geetha314753200834479115137175207
D,336853200834556
Cortazar34385320083407798123156185219240
FB,36925320083326780
Bruchfeld37865320083355695127165184218234273
A,407253200834155
et414153200833456
al.42115320083324760
Treatment42855320083325084116137195230269290
With45895320083577396134
Avacopan473753200834171104136173213246284
in503553200831452
ANCA-Associated51015320083418612716919123226028732535837340530475420083225595
Vasculitis31575420083366794126164179194216232258
With34305420083587496134
Kidney35805420083345190128163194
Involvement.37905420083145284121137170204262297335357370
Kidney41755420083355190128163195
Int43855420083155374
Rep.447554200833570109122
2025;10(8):2751-2765.461254200833468101136147177209228262280292327360393424442473506538572584
36.30475520085367288
Walsh315555200835789104130168
M,334355200835468
Collister34305520083407793108123149173206228
D,367755200834657
Zeng375355200833872110149
L,392255200833145
et398655200833457
al.40635520083314760
The414255200833372107
effects42695520083345473107140164191
of448055200833857
plasma45575520083385486113171203
exchange47805520083346596134167205244279
in507855200831553
patients51515520083387193108143181203230
with54015520083516689127
ANCA-associated304756200834289132176199233261289329363379412435470512
vasculitis:35815620083336795129168185201224241268281
an388556200833373
updated398056200833879121154177213254
systematic42565620083276190114149210244266283316
review45955620083215790107143197
and481456200833373114
meta-analysis.495056200835996119154177211251285301334363378406420
BMJ.539356200833694121134
2022;376:e064604.304757200833468101136148183215247260294330366402438474510522
37.30475820085367180
Lyons31485820083326098137164
PA,33325820083367388
Peters34405820083366992126147175
JE,36365820083245871
Alberici37285820083415696132153169201216
F,396558200833339
et402458200833557
al.41025820083324760
Genome-wide418358200834480118157216251274327342382417
association46205820083325986125158173205227243281320
study49615820083264988127159
of514158200833757
eosinophilic52195820083347310011515319223227028630475920083153062
granulomatosis31275920083386093131168184222280312334371398413439
with35845920083516689127
polyangiitis37305920083387793125158196235250265287303329
reveals40775920083215587122154169195
genomic429159200833873111149207222254
loci45645920083155386101
stratified46835920083265071104126141159176211250
by495259200833870
ANCA504059200834186127170
status.52295920083264982103141168181
Nat54295920083447799
Commun.304760200834077135193231269282
2019;10(1):5120.334460200833468100130143173205224256270282318349379413425
38.30476120085367288
Wechsler314861200835790123161187202237258
ME,341961200835488101
Akuthota353361200834171109131169207229262
P,380861200833539
Jayne38606120083255787126161
D,403461200834556
et410361200833456
al.41726120083314760
Mepolizumab424561200835489128167183198227265322355394
or465261200833758
Placebo47236120083355082114148187226
for49626120083185577
Eosinophilic50526120083327096111149187226265280295310342
Granulomatosis5407612008343659830476220083387590129187219241278305319346
with34086220083506688127
Polyangiitis.35506220083357288119152190229245260282297324337
N3902622008345
Engl396262200833371110125
J4102622008325
Med.414262200835490129142
2017;376(20):1921-1932.430062200833468100129139174206238257291325343355385415448480498529559592625637
39.30476320085367184
Wechsler314463200835790123161187202237258
ME,341563200835487100
Nair35286320083447792113
P,365463200833539
Terrier37066320083326384106121156177
B,389663200833548
et395663200833457
al.40256320083324760
Benralizumab409863200833570108129162177192221259317349388
versus44996320083326687114151177
Mepolizumab468963200835489128167183198227265322354394
for50956320083195678
Eosinophilic51856320083337097112149187227265280295310342
Granulomatosis30476420083446598136174189227286318340377403418444
with35076420083506688126
Polyangiitis.36496420083357287119152190229244259282297323337
N4001642008345
Engl406164200833371110125
J4201642008324
Med.424164200835489129142
2024;390(10):911-921.439864200833469101133145180213249269300332350362397429457476511544575585
40.30476520085367489
Chung315265200834078115153192
SA,33616520083327387
Langford346565200833164102142161199220258
CA,37406520083408296
Maz385365200835487116
M,398665200835468
et407065200833456
al.41436520083314760
2021421965200833468101133
American436865200834199134155171203236274
College46586520083407793108143182217
of489265200833756
Rheumatology/Vasculitis4965652008335731081462042362582953113493894214444845155413047662008331698499122137163
Foundation322366200833370108146185217239254292331
Guideline35676620083448297136171186201239274
for38546620083195678
the39456620083216095
Management405366200835487125157196231289324362384
of445066200833756
Antineutrophil451966200834179101116154189227249271308348386401417
Cytoplasmic49496620083406792129169185217243301316348
Antibody-Associated53106620083417910111615519430476720083387092133161188226259274306328361401
Vasculitis.34636720083366794126164179194216232258271
Arthritis37506720083416287125146161184199225
Rheumatol.399167200833573108146204236258295311324
2021;73(8):1366-1383.433067200833468101133141174208226260278290319349384419443474504538572585
41.30476820085366981
Biddle31486820083355189129144179
K,334668200833550
Jade34156820083255796131
J,356568200832436
Wilson-Morkeh36216820083577489115153192214270308330361395433
H,407468200834456
et415068200833456
al.42266820083324760
The430668200833271106
2025443268200833468101136
British4588682008335567294110136174
Society478168200833371104119153176209
for50106820083185678
Rheumatology510768200833674109147205237259296312350389421
management304769200835789127159198233291326363385
recommendations34456920083205487123182239274312351383405420458496522
for39806920083185677
ANCA-associated407069200834186127169190223249275314346361393415448488
vasculitis.45706920083326591123161176191213228254268
Rheumatology485169200833573108146203235257294310348387419
(Oxford).52836920083186496117154176214233244
2025;64(8):4470-4494.304770200833468101136147183219238272290302336373406439462499536569605617
42.30477120085366983
Suppiah314171200833268106144159189226
R,337771200833648
Mukhtyar343671200835491119157177210241261
C,370771200834052
Flossmann37697120083334683108133190220257294
O,407371200834757
et414071200833455
al.42067120083314557
A4273712008341
cross-sectional43257120083315187112137157182216247270284321358389402
study47387120083264884122153
of490171200833755
the49677120083215892
Birmingham50697120083365069126140176214251282338
Vasculitis541871200833565903047722008331668093114127151
Activity32087220083407092105136150170202
Score34197220083326397117149
version35787220083316382108121157193
33780722008334
in382472200831450
systemic38837220083265782103135190204233
vasculitis.41267220083316287117153166179200213237249
Rheumatology438572200833471104139195225245280294330367397
(Oxford).47927220083186292111147166202220229
2011;50(5):899-905.50317220083336595121127160192210241258268301333366388421454486497
43.30477320085367186
Suppiah315173200833270109149164196234
R,340373200833549
Flossman34707320083334785112139196229267
O,375573200834658
Mukhtyar383073200835593123162184217250272
C,411973200834053
et419073200833456
al.42647320083324760
Measurement434273200835590121148185206240298333372393
of475373200833756
damage482773200833871129161200235
in508073200831452
systemic51507320083265986109143201216248
vasculitis:541573200833265923047742008331698499122137163176
a3240742008332
comparison328974200833168126165198220235261300338
of364474200833757
the37187420083226095
Vasculitis38307420083366793126163179194216231258
Damage410574200834577135168207241
Index43647420083145291126158
with45397420083516689127
the46837420083226095
Combined479574200834077135174190228263302
Damage511574200834577135167206241
Assessment53747420083406895130304775200832653110145183205
Index.32677520083155392127159172
Ann345575200834179117
Rheum358775200833574109147204
Dis.38077520083456187100
2011;70(1):80-5.392375200833468100127136168202221253267279314349373407419
44.30477620085367490
Robson315376200833574113140178217
JC,33867620083246578
Dawson348176200834577128155193232
J,372976200832436
Doll37827620083458499115
H,391376200834457
et398676200833457
al.40597620083324760
Validation4136762008335668297136168190205243281
of443476200833756
the45077620083226095
ANCA-associated461876200834186127170191224250277315348363395417450490
vasculitis51247620083326591124161177192214229256
patient-reported5396762008339729310930477720083347294113135169209247269294327367
outcomes34297720083377698129166224259286
(AAV-PRO)373077200831960103137157194229277295
questionnaire.404077200833876111138161176214253291323338359393405
Ann446177200834179117
Rheum459377200833674109147205
Dis.48137720083456187100
2018;77(8):1157-1164.492977200833468100131143176210227260278290320348378411430461488519556568