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PŘEHLEDOVÉ479422001004388130181216258306358404446
ČLÁNKY525622001003973122176223272
Hypertenze477333001004885124159184213248285317351
u5140330010037
mužů519333001005997128166
a5376330010033
žen542533001003165103
|5584220010018
99564222001004284
/36318040010732
Vnitř3708804001074592111139166
Lék.3893804001074184122140
2026;72(2):99-1034053804001074487128170185227270291334356371415460490528568609
/47078040010732
VNITŘNÍ48058040010745106127171220280301
LÉKAŘSTVÍ5127804001074084130188235280325377399
www.casopisvnitrnilekarstvi.cz42580400107651332012142542953293774274464795215705896176436927117307748128548809159449871007102310631101
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Hypertenze425980027515228040852762071383095910631180
u16829800275122
mužů18519800275182310415541
a24699800275116
žen26329800275100216345
Barbora4251370013766125167232296338396
Nussbaumerová8431370013776140188236302361424519578620684741799
Centrum4251520013364117178213248309400
preventivní848152001336399153205258319354379432493518
kardiologie,13891520013352106141202227287313374436461515537
II.194915200133265276
interní2048152001332686121175211272296
klinika2368152001335178103164188239293
LF26841520013352105
a28121520013353
FN28891520013353123
v30351520013353
Plzni,3112152001335882129190215237
UK33721520013371130
v35261520013353
Praze3602152001335893146193248
Práce425203001215386135181231
shrnuje676203001214096129186241266317
současné1013203001214096152198248288344395
poznatky14282030012157114157213262295343394
týkající1842203001213384132183207231277301
se2163203001213991
epidemiologie,22742030012150108132190241326350406431487544569620641
diagnostiky,2935203001215680129186242298338373397445496513
léčby3468203001212375121178226
a37142030012148
potenciálu37822030012157114147198254300324373397453
rozvoje4255203001213388131183238262313
poškození45882030012157114154202256299350407431
cílových503920300121456995151199251295351
orgánů54102030012155894252170012156104160215
při660217001215690114
hypertenzi7932170012155101160211245281331387431455
u12682170012154
žen1342217001214293149
a15112170012148
mužů15782170012183138182237
s18352170012139
důrazem18942170012156111144193237287371
na22852170012155104
rozdílnost2408217001213388130187211237293348388423
mezi28502170012183134178202
pohlavími,30722170012156113169193242289313397421442
vycházející3533217001214899144199248292343367391436460
z40122170012143
aktuálních4074217001214896132187236260316340385440
odborných45342170012154112169226259316362406462
doporučení.50152170012156112170226259315361410467490512
Ženy4252310012155106162209
mají6612310012183132157181
v8692310012148
nižším944231001215579123165189273
věku1244231001214898146203
nižší1474231001215579123165189
prevalenci1690231001215791142190240264315372418442
hypertenze,21592310012155102160213246283334390434485506
ale2692231001214873124
po28432310012157114
menopauze29832310012184135192248306356411456507
mohou35162310012184140197253309
i38522310012123
převažovat3902231001215791142190240284340388437471
nad43992310012156105163
muži.45882310012184140183208230
Ženy48442310012156106163209
s50802310012140
vysokým51462310012148100141197245296382
normálním4252450012155112146230279304360384468
tlakem917245001213357106154204289
mohou12292450012184140197253309
mít15622450012183108142
větší1727245001214999133174199
pravděpodobnost,1949245001215791141188245296354411469525583640696736771793
že2766245001214394
se2884245001213991
u29982450012156
nich3077245001215680126182
vyvine3283245001214899152177233284
hypertenze,35912450012156102161213247284334391435486507
než41212450012156107152
u42962450012155
mužů.43752450012184139183239261
Ženy46592450012156106163209
mohou48922450012183139196252309
být52252450012156104141
náchylnější539024500121551044252590012145101147173229280305345369
k8212590012147
poškozeních8952590012157114154202257300351407431477533
cílových145525900121456995152200251296352
orgánů1835259001215488145194250306
při2168259001215791115
hypertenzi23112590012155102160212246283334390434459
více2797259001214873119169
než29932590012155107151
muži31712590012184139183208
a34062590012148
současně3482259001213995152198247287343395
u39042590012155
nich3986259001215680126182
hypertenze41952590012156102161213247284334391435486
může47082590012183139183234
představovat4969259001215791142200240275325372427475525558
vyšší4252730012148100140180204
riziko651273001213257101125173228
rozvoje900273001213388131183238263314
ischemické1236273001212363109165217301325371419469
choroby17262730012145101157191247305352
srdeční2100273001213972130181228284308
a24292730012148
cévní2499273001214595143200225
mozkové27452730012183140182230285333383
příhody3150273001215791115173229288336
než35082730012155107151
u36802730012155
mužů.37572730012183139183239260
Základ40392730012155105153179228286
terapie4346273001213383117167225249300
tvoří4668273001213385140173198
u48872730012155
obou49642730012155113169226
pohlaví52112730012157114171195244292317
režimová425287001213384128152236292341390
opatření8432870012154113162196229280337361
a12312870012149
farmakoterapie1307287001212979113198247294349383433467517574599650
podle19852870012157113172196247
aktuálních2260287001214896133189238262318342388444
doporučení27322870012156112170227261317363413470494
(inhibitory3254287001212852108164188246270304360393445
ACE37262870012162118167
(angiotenzin3921287001212874131188212268302352409453477533
konvertujícího44822870012147102158206256290327382407431477501559615
enzymu)/51252870012150107151202287343369402
sartany,425301001214091125162213270317334
diuretika,790301001215782138172224259283332383405
blokátory1226301001215783140189240274330364416
kalciových1673301001214798123170194251300352398455
kanálů,2158301001214899156205230287309
betablokátory),24983010012157110145195254279336385436470526561613641661
s31903010012140
výjimkami32603010012149101127152237286337422446
v37373010012149
těhotenství3817301001213384141198233284341382417470495
a43433010012148
při4422301001215892117
jeho4570301001212476134191
plánování.4792301001215783132189246295345402427449
Léčba5272301001214799146204255
hypertenze4253150012155102160212246283333390434485
u9303150012155
žen1005315001214293150
musí11753150012183139179203
zohledňovat1398315001214398155179231289345401449498532
reprodukční1950315001213283141175230288344392436492516
plán,2486315001215782131187209
možnost27153150012183139182239295335370
těhotenství3105315001213383139195229279336376411462487
a36123150012148
změny36803150012143127179235281
spojené3981315001214097154179230287338
s43393150012140
menopauzou.43993150012183134191247305355410454510566588
Personalizovaný50073150012153102136177233290339363387431487425329001214898154200
přístup646329001215791116156190246304
a9713290012148
využití10403290012149100157201225259284
nejnovějších13453290012155107131188244292342367407431476533
doporučení18993290012156112170227261318363413470494
mohou24143290012184140197253309
zlepšit2744329001214368119177217241275
kardiovaskulární3040329001214797131188212268316366406454510535583617674698
prognózu.3759329001215791146204260317359416437
K42183290012154
ozřejmění4293329001215598131182207291342399423
pohlavních47373290012157114171195244292349373419475
rozdílů5233329001213288131188212239294
u4253430012155
hypertenze5033430012156102161213247284334391435486
je1012343001212476
třeba1111343001213366117175225
další13593430012156106130170194
výzkum.15763430012148100146194250335357
Klíčová425360001235885111155211261312
slova:761360001234268124174225248
hypertenze,10333600012155101159210243279328384427477496
mezipohlavní15543600012183134177201257313369392440487543566
rozdíly,2144360001213388130186209235282298
těhotenství,2466360001213383138193226276331370404455479499
farmakoterapie,2990360001212978110194242289343375425458506563586637657
hormonální36713600012155111143227282338386410465488
léčba,4183360001212474120176225246
menopauza,44533600012184134190245302351405448498519
odborná49973600012155112169224257313361
doporučení.538236000121571124253740012157113146201246295351374394
Hypertension4253990015083151220283332381444513568603670738
in12013990015033101
women13413990015091157257320389
and17683990015063132201
men20073990015099162231
This4254190012150106129168
paper6214190012157106163214247
summarizes896419001213994177260308341364407457497
current1421419001214599132165215270303
knowledge17524190012147104159232256306363419470
on22504190012155110
the2388419001213389139
epidemiology,25554190012150107131188238321345400424479536583599
diagnosis,3182419001215780128184239294333356395417
treatment,3627419001213365115163196279329385417439
and40944190012148103160
the4282419001213388138
potential44494190012156112145194250283306353377
development48544190012156107154203227282340423474529562
of5444419001215584
target425433001213382114170220254
organ705433001215588144192247
damage9794330012156104187235291342
in1347433001212479
hypertension14524330012156101159210243279328384423446501556
in2035433001212378
women21404330012174128211262318
and24844330012148104160
men,26714330012183134189210
with2908433001217397130185
an31204330012148103
emphasis32504330012150133190246294333356395
on36724330012155110
sex-related3809433001213990137166200250274322354403461
differences,4296433001215780109142192225275330375424464485
based48084330012156105144195252
on50874330012154110
current5224433001214499132165215270303
clinical42544700121456890145168212261284
guidelines.7274470012155110133189239263286340391430451
Women11964470012184136219269325
have15384470012156103150198
a17544470012148
lower1820447001212378150200232
prevalence2070447001215789139186234257307363407456
of2544447001215483
hypertension26454470012155101158209241277326381420443497553
at3215447001214881
a33134470012148
younger33794470012147101156211266316349
age;37464470012148103153173
however,39364470012156110183232279328361376
after4330447001214877113162195
menopause,45424470012183134189244300349403442492512
prevalence5072447001215689138186234257307362407456
may4254610012183132177
equal6264610012150107162210233
or882461001215588
even994461001215097147202
exceed1220461001215097141190241298
that1541461001213388136169
in1733461001212479
men.18354610012184134190211
Women20694610012185138221272327
with2420461001217397130185
high-normal2629461001215578134190222278333366450498522
blood3174461001215781136192249
pressure3446461001215790140180219273306355
may38254610012183131177
be40254610012157108
more41574610012183138171221
likely440146100121244794142166214
to4638461001213387
develop47494610012156107154203227282340
hypertension51124610012155101159210243278328383425475001214062118173
than623475001213389137192
men.8404750012183134190211
Compared10764750012158111195252301333383440
with1541475001217498131186
men,17524750012183134190210
women19884750012173127211262317
may23304750012184132178
be25334750012157108
more26664750012183138171221
susceptible2912475001214094133179228285318341397421472
to3409475001213387
hypertension-related35214750012156101159210243279328384423446501556589622672696744777826883
target4429475001213382115170221254
organ4708475001215588144192247
damage,49804750012157105188236292342362
and53674750012148104160
hypertension4254890012155101159210243279328383422445500556
in1002489001212479
women11024890012174128212262318
may14414890012183132177
be16394890012157108
associated1768489001214988127182228251298331380438
with2227489001217397130185
a24334890012149
higher2503489001215579134190240273
risk279748900121335696142
of2960489001215584
ischemic3066489001212362107162213296319364
heart34514890012156106154187223
disease3695489001215680119169217256307
and40234890012148103160
stroke.4204489001214074106161208257277
In425503001212479
both5315030012157113145201
sexes,758503001214090138186226247
the1032503001213388138
cornerstone1197503001214599132187238271311345399455505
of1729503001215584
therapy1840503001213388138171220276323
consists2189503001214599155194217256290330
of2546503001215584
lifestyle265750300121234675126165199249273323
interventions3007503001212479111160193244294349381405460515554
and35885030012148103160
pharmacological37755030012157113161193277325370424448503559583627676699
treatment4501503001213366116164196279330386418
in4946503001212378
accordance5051503001214893137190223279327383428477
with425517001217396129184
current626517001214599131164213268300
guidelines9445170012155109132188238262284339389428
(ACE1389517001212988143191
inhibitors/angiotensin1597517001212478133156212235268321354394428472527583605660692741796835857912
receptor2526517001213382127176232265319351
blockers,2895517001215680135180226274306346367
diuretics,3280517001215678133165214247270314354375
calcium3672517001214593116161183237320
channel4009517001214599147201256306330
blockers,4356517001215780135180226275307347368
and47415170012148103159
beta-blockers),49175170012157107140189220278301356401447495528568592611
with425531001217497130186
specific629531001213996147192215245271316
exceptions963531001215097141190247280303358414453
during14345310012156111143167222278
pregnancy1730531001215790140196252300355400450
and21985310012148103160
pregnancy2376531001215790139196252299355400449
planning.2843531001215781129185240263318374395
The32565310012150106156
management34305310012184132187235291341425476531564
of4012531001215484
hypertension41145310012155101158209242278327383422445500556
in4688531001212378
women47845310012174128212262318
must51205310012183138177211
take5349531001213382129178
into425545001212379111165
account618545001214893136190245301333
reproductive978545001213383140173228285339385420443491540
plans,1546545001215781129184223244
the1818545001213388138
possibility19845450012157113152191214271294318340374423
of2435545001215584
pregnancy,2547545001215789139196251299355400449465
and30405450012148103160
menopause-related32285450012183134189244301350405444494528562611635683716765822
changes.40785450012145100148203259310349370
A44765450012161
personalized45655450012157108141181236292340363386429479536
approach51295450012148105162195250298343398
and4255590012148103160
the604559001213389139
implementation7625590012124107163187238321372427460509541564619675
of1456559001215584
the1559559001213389139
most17175590012184139178212
recent1948559001213383128177233265
guidelines22335590012156110133190240264287343393432
may26855590012183131177
improve28815590012123106163196251298347
cardiovascular3247559001214594126182205260308356395440495518566599
prognosis.3865559001215790144201257312351374413434
Further43185590012149102134170225276309
research4646559001213382122172220253297352
is5017559001212463
needed50995590012156106157214265322
to5440559001213387
elucidate425573001215074129174197253301334383
sex829573001214090138
differences988573001215679109142192225275330375424464
in1473573001212378
hypertension.15735730012155101158209242278328383422445500556577
Key4255900012358108158
words:6045900012374130166224266290
hypertension,9155900012155101159210243279328384423445500556577
intersex1513590001212479111160193234284331
difference,1866590001215679109141192224274330375424444
pregnancy,2331590001215790140196252300355400450466
pharmacotherapy,28185900012157113161193277325370424456512562595643700746762
hormonal36025900012155110143227282338386409
treatment,4032590001213366116164196280330386418439
menopause,44935900012183133189244301350405444494514
guidelines.50285900012156111134191241265288343394433455
Úvod4256330013874137198262
Hypertenze565650001075696146190216247289336373415
patří997650001074990117143162
mezi11756500010773117153172
nevýznamnější1364650001074891131174212261301374421465483515533
rizikové191365000107274682101138185224267
faktory2196650001072465103133179206248
kardiovaskulárních246165000107377910515317121925829933236941742566400107196086135153193241
(KV)683664001072468118145
onemocnění.845664001074796140214262303351395443462478
Prevalence1339664001074571114155196215259307348390
a17466640010741
klinický180366400107385977125144184222264
průběh2084664001075077125174219267
včetně2368664001074080122150198242
pravděpodobnosti2627664001074976118158206250425678001075099149197247296344378407426
poškození868678001074999132170217252295343362
cílových124767800107405979128168211251299
orgánů1563678001074875123164212259
se1839678001073378
u19346780010747
žen1998678001073780128
a21436780010741
mužů22016780010773121158206
liší24246780010719377088
v25296780010741
závislosti2587678001073678118137170189237271300318
na3047636001074889
věku,3153636001074184122170186
reprodukčním3356636001072769119146193243291329368416434508
statusu3881636001073463104131179212259
a41576360010741
hormonálních4215636001074997124198247296336355403421462510
vlivech.474263600107406079120163204252268
Tento5028636001074180128155202
přehled5247636001075076119167186230280
shrnuje3047650001073481108157204223267
moderní33356500010774122172216243292310
přístupy366665000107507796129158206255295
k39826500010738
diagnostice4041650001074968108157205254287316335375418
a44806500010741
léčbě4542650001071963104154198
u47616500010748
žen,4830650001073780128143
včetně4994650001074181123151199243
specifik5258650001073483128169188212232269
v30476640010741
období3104664001074898147195245264
okolo3385664001074786133152200
těhotenství3601664001072870118166193236284316345388408
a40256640010741
peri-/postmenopauze,4082664001075094121140167198245294327356429473521569619661708744787801
na4900664001074888
základě5005664001073678116136177226269
evropských52916640010743841111582073047678001073471114154202
a32686780010741
mezinárodních33296780010774118155174222263289336387435453493541
doporučení3890678001074997147196223272312354403421
(1,433167800107246374
2).442567800107436679
MUDr.425740009562112164189200
Barbora64374000954077101146190214252
Nussbaumerová,91274000955194124154198235278343383407449485523537
Ph.D.14677400095408297150163
Centrum42575200954684127151175219284
preventivní72775200954468107143182225250267304348364
kardiologie,11097520095347295139156199216260304321361374
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