Vnitr Lek 1991, 37(9-10):761-767
[Multicenter study with gliquidone in type 2 diabetes mellitus].
- Endokrinologický ústav, Lubochna.
The effectiveness and tolerance of the new sulphonyl urea antidiabetic gliquidone (commercial name Glurenorm) was tested by three-month administration of this preparation in a group of 39 type 2 diabetics. Gliquidone proved a medium-strength beta-cytotropic antidiabetic preparation. As to side-effects, the authors noted only dyspepsia in one patient (2.5%). Symptomatic hypoglycaemia did not develop in any of the patients. In the subgroup of six patients with diabetic nephropathy the indicators of renal functions did not deteriorate. In a sub-group of 6 patients with concurrent hepatopathy the originally elevated gamma-glutamyl transpeptidase activity receded. The authors confirmed thus the good tolerance of gliquidone in diabetes associated with nephropathy and diabetes with hepatopathy.
Keywords: Adult; Aged; Diabetes Mellitus, Type 2, blood, ; Female; Humans; Hypoglycemic Agents, adverse effects, ; Male; Middle Aged; Sulfonylurea Compounds, adverse effects,
Published: September 1, 1991 Show citation