Vnitr Lek 2010, 56(12):1292-1295

Extremly low SHBG level in consequence of Pro156Leu SHBG polymorphism - case reports of two women with polycystic ovary syndrome

M. Vaňková*, S. Pražáková, P. Lukášová, J. Včelák, D. Vejražková, O. Bradnová, K. Dvořáková, J. Vrbíková, B. Bendlová
Oddělení molekulární endokrinologie Endokrinologického ústavu Praha, ředitel doc. MUDr. Vojtěch Hainer, CSc.

Presented case reports illustrate clinical manifestations of two women with polycystic ovary syndrome who had extremly low serum SHBG levels (Sex Hormone Binding Globulin) due to homozygote carriership of the rare Pro156Leu SHBG polymorphism.

Keywords: SHBG; polymorphism; polycystic ovary syndrome

Received: October 4, 2010; Published: December 1, 2010  Show citation

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Vaňková M, Pražáková S, Lukášová P, Včelák J, Vejražková D, Bradnová O, et al.. Extremly low SHBG level in consequence of Pro156Leu SHBG polymorphism - case reports of two women with polycystic ovary syndrome. Vnitr Lek. 2010;56(12):1292-1295.
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