Vnitr Lek 1992, 38(2):155-159

[Feldene in local therapy of deforming gonarthroses].

J Vachtenheim: Vnitrní oddĕlení II, nemocnice s poliklinikou OUNZ, Jihlava.

The author submits the results of Feldene gel therapy which contains 5 mg piroxicam per 1 g. The preparation was applied to patients with deforming gonarthrosis, always on one joint three times per day for two weeks. The evaluation was made before the unset of treatment and on the 7th and 14th day. It was an open clinical therapeutic trial. In 97.5% the tolerance was excellent. Undesirable manifestations developed only in one female patients who had sensations of irritation which disappeared in three days and interruption of treatment was not necessary. The authors evaluated pain, mobility, required assistance during change of position-sitting and standing up and when climbing stairs. The evaluation was made by the physician and the patient. Significant results were achieved in particular as regards pain but also in the other parameters. In more than 90% regression of all evaluated criteria was recorded. The preparation is evaluated very favourably. It helps not only in treatment proper but has also a comprehensive effect. Feldene gel is an important asset to local treatment in rheumatology and will be most probably valuable also in orthopaedics, surgery and sports medicine.