Vnitr Lek 1993, 39(2):136-142

[The effect of creatine phosphate (Neoton) in acute myocardial infarct (a prospective multicenter pilot study].

M Stejfa, K Zeman, L Groch, J Marek, J Komárek, T Janota, F Vávra, F Kölbel, I Charvát, O Weinbergová

I. interní klinika FN u sv. Anny, Brno.

The authors investigated in a group of 106 patients with a first myocardial infarction treated by thrombolysis the effect of i.v. administration of creatine phosphate (a new drug with cardioprotective action--Neoton Alfa Schiapparelli Wassermann Co). In the course of treatment electrocardiographic changes were recorded and the presence of arrhythmias examined by the Holter technique. The Neoton group displayed a statistically insignificant but nevertheless obvious trend of electrocardiographically less serious forms of infarction and a lower incidence of infarctions, as compared with the control group.

Keywords: Female; Humans; Male; Middle Aged; Myocardial Infarction, drug therapy, ; Phosphocreatine, therapeutic use, ; Pilot Projects; Prospective Studies; Thrombolytic Therapy

Published: February 1, 1993  Show citation