Vnitr Lek 1993, 39(2):172-177

[The present status of nitrates in the treatment of ischemic heart disease].

M Stejfa, J Vítovec
I. interní klinika FN u sv. Anny, Brno.

The authors describe the development of nitrates from substances of the first generation (nitroglycerin and isosorbit dinitrate) to the second generation (isosorbit-5-mononitrate). They explain the mechanism of their action, haemodynamic effects and the problem of nitrate tolerance. Indications of their rational use are given.

Keywords: Coronary Disease, drug therapy, ; Hemodynamics, drug effects, ; Humans; Nitrates, pharmacology,

Published: February 1, 1993  Show citation

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Stejfa M, Vítovec J. [The present status of nitrates in the treatment of ischemic heart disease]. Vnitr Lek. 1993;39(2):172-177.
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