Vnitr Lek 1995, 41(6):367-370

[Serum gastrin and somatostatin in diseases of the stomach].

J Payer, M Huorka, I Duris, V Randus, P Ondrejka, H Kratochvíµová
I. interná klinika FN, Bratislava.

Gastrin and somatostatin are enterohormones which influence several physiological processes in the gastrointestinal tract. Gastrin has a pro-malignant and pro-ulcerogenic effect, while somatostatin deficiency has a similar effect. The authors examined in their investigation the 24-hour secretion of both hormones in patients with gastric ulcer and atypical gastric conditions. They revealed a significant difference in the 24-hour somatostatin level which was higher in patients with atypical gastric conditions (p < 0.05). The finding may suggest a more intense reaction of somatostatin to malignant than to non-malignant disease. In the other compared parameters no statistically significant difference was revealed.

Keywords: Adult; Aged; Female; Gastrins, blood, ; Humans; Male; Middle Aged; Peptic Ulcer, blood, ; Somatostatin, blood, ; Stomach Diseases, blood,

Published: June 1, 1995  Show citation

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Payer J, Huorka M, Duris I, Randus V, Ondrejka P, Kratochvíµová H. [Serum gastrin and somatostatin in diseases of the stomach]. Vnitr Lek. 1995;41(6):367-370.
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