Vnitr Lek 1996, 42(8):537-539

[Determination of free radical activity in workers at risk for styrene exposure].

J Kohout, V Holecek, V Machartová, J Racek, Z Jerábek, V Senft
Klinika pracovního lékarstvi, FN Plzen.

The authors examined indicators of the effect of free radicals (MDA, SOD, GSHPx, selenium) in 38 workers exposed to styrene. They revealed a statistically significant (p < 0.01) correlation of SOD activity and the period of exposure to styrene and also a statistically significant correlation (p < 0.05) between urinary selenium excretion and the period of exposure to styrene as well as a statistically significant correlation (p < 0.01) between the MDA serum concentration and urinary selenium excretion. There is no statistically significant difference between the MDA plasma concentration among smokers and non-smokers, the SOD activity is significantly higher in non-smokers (p < 0.05). Based on the revealed findings the authors assume that free radicals may also play a part in the action of styrene on the organism.

Keywords: Adult; Female; Free Radicals, metabolism, ; Glutathione Peroxidase, blood, ; Humans; Male; Malondialdehyde, blood, ; Middle Aged; Occupational Exposure; Risk Factors; Selenium, metabolism, ; Styrene; Styrenes, adverse effects, ; Superoxide Dismutase, blood,

Published: August 1, 1996  Show citation

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Kohout J, Holecek V, Machartová V, Racek J, Jerábek Z, Senft V. [Determination of free radical activity in workers at risk for styrene exposure]. Vnitr Lek. 1996;42(8):537-539.
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