Vnitr Lek 1998, 44(7):409-414

[The short-acting insulin analog Lispro (Humalog) in the treatment of diabetes--comparison of preprandial and postprandial administration and comparison with treatment using Humulin R].

J Perusicová, J M Svehelka

Diabetologické centrum VFN, III. interní klinika 1, Praha.

The results of a clinical trial comprising 162 type 1 and 2 diabetics who took for 12 weeks Humalog in cartridges revealed that administration of this insulin before or 20 minutes after a meal does not affect the blood sugar level in a major way. None of the patients developed after Humalog administration local or general allergic manifestations. Hypoglycaemic episodes grade I and II were not more frequent during treatment with human insulins. The mean compensation of diabetes (HbA1c) remained unchanged. 80% of the diabetics are statistically significantly satisfied with Humalog treatment as compared with Humulinem R administration.

Keywords: Adult; Diabetes Mellitus, drug therapy, ; Drug Administration Schedule; Female; Humans; Hypoglycemic Agents, administration & dosage, ; Insulin, administration & dosage, ; Insulin Lispro; Male

Published: July 1, 1998  Show citation