Vnitr Lek 2005, 51(2):167-174

Pulse pressure in the young population detected by ABPM and it's relation to metabolic and anthropometric parameters

J. Pařenica^1,*, L. Pinková², O. Ludka¹, P. Fráňa², H. Němcová², J. Špinar¹

¹ Interní kardiologická klinika Lékařské fakulty MU a FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Jindřich Špinar, CSc.

² II. interní klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta doc. MUDr. Miroslav Souček, CSc.

Elevated value of pulse pressure (PP) is a predictor of increased cardiovascular mortality and morbidity. Ambulatory twenty four hour blood pressure monitoring (ABPM) shows a close correlation with end organ damage comparing with office blood pressure. The aim of this trial was to determine mean values of PP detected by ABPM in population aged 18-30 years, to determine variability of PP during day, to determine correlation between PP and systolic and diastolic blood pressure, heart rate and some risk factors of atherosclerosis. We have examined 252 probands (average age 23.6 ± 3.8, 55.2% were women). In this study the men population had significantly higher value of PP compare with women (53.4 ± 6.2 mm Hg vs 45.5 ± 4.5 mm Hg, p < 0.01). There was not different between ABPM and office value of PP. During day there was minimal variability of PP. The value of PP correlated with systolic but no with diastolic BP (correlation coefficient of PP and systolic blood pressure r = 0.62 for young men, r = 0.59 for young women, both p < 0.01). We have found inversion correlation of PP and HDL (r = -0.22, p < 0.05) for men and correlation of PP and BMI, waist circumference and waist-hip ratio for women on the border of statistical significance.

Keywords: pulse pressure; ambulatory twenty four hour blood pressure monitoring; young population

Received: April 6, 2004; Accepted: April 14, 2004; Published: February 1, 2005  Show citation