Vnitr Lek 2011, 57(12):1038-1044

Survival of patients after TIPS in the University Hospital Hradec Kralove

Š. Šembera^1,*, V. Jirkovský², T. Fejfar², V. Šafka², O. Renc³, J. Raupach³, V. Chovanec³, M. Lojík³, A. Krajina³, P. Hůlek²

¹ Lékařská fakulta UK Hradec Králové, děkan prof. MUDr. RNDr. Miroslav Červinka, CSc.

² II. interní klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Jaroslav Malý, CSc.

³ Radiologická klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Pavel Eliáš, CSc.

Aim:
To analyze survival of patients after TIPS (transjugular intrahepatic portosystemic shunt).


Patient sample and methodology:
Between September 1992 and August 2010, TIPS was created in 848 patients of the University Hospital Hradec Kralove. These patients were divided into groups. Survival was analyzed using Kaplan-Meier survival curves. Differences between groups were evaluated using log-rank test.

Results:
Ten percent of patients do not survive one month after TIPS, 40% of patients survive 5 years and 20% of patients survive 10 years. There were statistically significant differences between groups divided according to Child-Pugh classification (A vs B p = 0.0053; B vs. C p < 0.0001), indication for surgery [prevention of bleeding recurrence differed from refractory ascites (p = 0.0001) and the indication to stop acute bleeding (p = 0.026)]; aetiology of the liver disease [patients with alcoholic cirrhosis differed from patients with Budd-Chiari syndrome (p < 0.0001) and from patients with chronic viral hepatitis (p = 0.024)].

Conclusion:
Survival of patients after TIPS is influenced by Child-Pugh score, indication and aetiology of the liver disease.

Keywords: transjugular intrahepatic portosystemic shunt; liver disease; Child-Pugh score; indication

Received: October 2, 2011; Published: December 1, 2011  Show citation