Vnitr Lek 2012, 58(5):386-389

Vitamin D and cardiovascular risk

O. Mayer jr.
II. interní klinika Lékařské fakulty UK a FN Plzeň, přednosta prof. MUDr. Jan Filipovský, CSc.

The pathogenesis of cardiovascular disease is without any doubt multifactorial, and it is generally accepted, that conventional risk factors determined only about 80% of cardiovascular risk. There is accumulating evidence that vitamin D exerts important pathophysiological effects on cardiovascular system. Low vitamin D was associated with increased cardiovascular risk in several reports. This review summarizes recent epidemiological evidence and possible pathophysiological mechanism for a role of low vitamin D in cardiovascular diseases. Moreover, available data concerning vitamin D supplementation are depicted.

Keywords: vitamin D; cardiovascular disease; vascular calcification; arterial stiffness; cardiomyocyte

Received: September 30, 2011; Published: May 1, 2012  Show citation

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Mayer O. Vitamin D and cardiovascular risk. Vnitr Lek. 2012;58(5):386-389.
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