Vnitr Lek 2012, 58(5):393-395

Vitamin D and neurological diseases

J. Polívka^1,*, J. Polívka jr.², M. Peterka¹, V. Rohan¹, P. Ševčík¹, O. Topolčan³

¹ Neurologická klinika Lékařské fakulty UK a FN Plzeň, přednosta MUDr. Jiří Polívka, CSc.

² Fakulta aplikovaných věd Západočeské univerzity Plzeň, děkan doc. Ing. František Vávra, CSc.

³ Oddělení nukleární medicíny FN Plzeň, úsek imunoanalýzy, přednosta MUDr. Dagmar Slípková

We provide an overview of the association between vitamin D and some neurological diseases where the correlation has repeatedly been described. The majority of literature refers to cerebrovascular diseases, followed by multiple sclerosis and cognitive disorders. Vitamin D hypovitaminosis might be associated with the diseases directly or it might contribute to the disease risk factors (typically in cerebrovascular events). Vitamin D hypovitaminosis may also play a role in patients with residual functional involvement due to a neurological disorder (movement disorders, lack of self-sufficiency) and worsen functional status owing to muscle weakness, instability and falls.

Keywords: vitamin D; cerebrovascular disorders; multiple sclerosis; cognitive disorders

Received: October 24, 2011; Published: May 1, 2012  Show citation