Vnitr Lek 2014, 60(5-6):514-519
Extraadrenal paraganglioma
- 1 V. interná klinika LF UK a UN Bratislava, Slovenská republika, prednosta prof. MUDr. Juraj Payer, PhD., FRCP
- 2 Urologická klinika LF UK a UN Bratislava, Slovenská republika, prednosta prof. MUDr. Ján Breza, DrSc.
Various symptoms may be present in pheochromocytoma and paraganglioma. The tumor can imitate numbers of diseases and often leads to misdiagnosis. Current advances in laboratory techniques (determination of free plasma metanephrines), tumor localization (using positron emission tomography) and surgery techniques together with better understanding of pathophysiology and genetics (role of subunit B of succinate dehydrogenase) lead to earlier diagnosis, changes in strategy and treatment options. Authors introduce case report of retroperitoneal paraganglioma in 59 years old patient. In conclusion, interdisciplinary cooperation in diagnosis and treatment was successful.
Keywords: diagnosis; paraganglioma; pheochromocytoma
Received: February 16, 2013; Accepted: February 19, 2014; Published: May 1, 2014 Show citation
References
- Elder E, Elder G, Larsson C. Pheochromocytoma and functional paraganglioma syndrome: no longer the 10% tumor. J Surg Oncol 2005; 89(3): 193-201.
Go to original source...
Go to PubMed...
- Pacák K. Feochromocytóm. Galén: Praha 2008. ISBN 978-80-7262-519-2.
- Daub KF. Pheochromocytoma: challenges in diagnosis and nursing care. Nurs Clin North Am 2007; 42(1): 101-111.
Go to original source...
Go to PubMed...
- Pacák K, Lazúrová I et al. Endokrinní nádory nadledvin v současné klinické praxi. Galén: Praha 2011; 1: 131-133. ISBN 978-80-7262-819-3.
- Lenders JW, Eisenhofer G, Mannelli M et al. Pheochromocytoma. Lancet 2005; 366 (9486): 665-675.
Go to original source...
Go to PubMed...
- Amar L, Servais A, Gimenez-Roqueplo AP et al. Year of diagnosis, features at presentation, and risk of recurrence in patients with pheochromocytoma or secreting paraganglioma. J Clin Endocrinol Metab 2005; 90(4): 2110-2116.
Go to original source...
Go to PubMed...
- Neumann HP, Bausch B, McWhinney SR et al. Germ-line mutations in nonsyndromic pheochromocatoma. N Engl J Med 2002; 346(19): 1459-1466.
Go to original source...
Go to PubMed...
- Mantero F, Terzolo M, Arnaldi G et al. A survey on adrenal incidentaloma in Italy. Study Group on Adrenal Tumors of the Italian Society of Endocrinology. J Clin Endocrinol Metab 2000; 85(2): 637-644.
Go to original source...
- Manger WM, Gifford RW. Pheochromocytoma. J Clin Hypertens (Greenwich) 2002; 4(1): 62-72.
Go to original source...
Go to PubMed...
- Pacak K, Linehan WM, Eisenhofer G et al. Recent advances in genetics, diagnosis, localization and treatment of pheochromocytoma. Ann Intern Med 2001; 134(4): 315-329.
Go to original source...
Go to PubMed...
- Pacak K, Ilias I, Adams KT et al. Biochemical diagnosis, localization and management of pheochromocytoma: focus on multiple endocrine neoplasia type 2 in relation to other hereditary syndromes and sporadic forms of the tumour. J Intern Med 2005; 257(1): 60-68.
Go to original source...
Go to PubMed...