Vnitr Lek 2016, 62(4):334-337

DRESS syndrome

Monika Adamcová*, Igor Šturdík, Tomáš Koller, Juraj Payer
V. interná klinika LF UK a UN Bratislava, Nemocnica Ružinov, Slovenská republika

DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is severe drug-induced allergic-type reaction which occurs few days to weeks after taking a drug in a predisposed patient. Organ damage, eosinophilia and skin rash are typical at presentation. Corticotherapy is often necessary in severe cases. In this report we describe a case of 56-year old female with fever, elevated liver tests and skin rash. DRESS syndrome was diagnosed and allopurinol was indentified as a causative drug. Due to possible fatal outcome, DRESS syndrome should be considered in a differential diagnosis of all patients presenting with similar signs and symptoms.

Keywords: allopurinol; DRESS syndrome; hepatopathy

Received: September 30, 2015; Accepted: January 8, 2016; Published: April 1, 2016  Show citation

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Adamcová M, Šturdík I, Koller T, Payer J. DRESS syndrome. Vnitr Lek. 2016;62(4):334-337.
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