Vnitr Lek 2016, 62(7-8):568-574

Sepsis - how to recognize and what to focus on - back to basics in the light of the new definition

Jan Horák1,2, Martin Harazim1, Thomas Karvunidis1,2, Jaroslav Raděj1,2, Ivan Novák1, Martin Matějovič1,2,*
1 I. interní klinika LF UK a FN Plzeň
2 Biomedicínské centrum LF UK, Plzeň

Sepsis is the primary cause of death from infection. However, its early recognition remains a fundamental challenge in clinical practice. In February 2016, a newly revised sepsis definition has been published (SEPSIS-3). Sepsis has been redefined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In this article, we introduce the updated definition of sepsis, discuss its pros and cons and suggest practical implications. The emphasis is put on basic and comprehensive clinical assessment.

Keywords: definition; early recognition of sepsis; infection; sepsis; septic shock

Received: July 18, 2016; Accepted: August 1, 2016; Published: July 1, 2016  Show citation

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Horák J, Harazim M, Karvunidis T, Raděj J, Novák I, Matějovič M. Sepsis - how to recognize and what to focus on - back to basics in the light of the new definition. Vnitr Lek. 2016;62(7-8):568-574.
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