Vnitr Lek 2019, 65(5):377-378 | DOI: 10.36290/vnl.2019.067
Use of idarucizumab in clinical practice: a case report
- Centrum kardiovaskulární a transplantační chirurgie, Brno
Budd-Chiari syndrome is a serious condition which in chronic course leads to the development of liver cirrhosis. Anti-coagulant treatment of this syndrome is fully indicated and in the treatment can be used dabigatran. Advanced cirrhosis of the liver due to this disease can be an indication for a liver transplant. In this case, it is a great advantage the existence of an antidote to dabigatran (idarucizumab) in order to adjust the coagulation ratios and prevent bleeding disorders. Referred to a case report describes the first experience with idarucizumab in context with liver transplant in a patient with Budd-Chiari syndrome
Keywords: antidote; bleeding; dabigatran; direct oral anticoagulants (DOAC); idarucizumab; liver transplant
Received: August 28, 2018; Accepted: November 7, 2018; Published: May 1, 2019 Show citation
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