Vnitr Lek 2019, 65(6):416-424 | DOI: 10.36290/vnl.2019.075

Extracorporeal removal techniques in toxicology: part 1

Jaroslav Raděj1,2,*, Jan Horák1,2, Martin Harazim1,2, Martin Matějovič1,2
1 I. interní klinika LF UK a FN Plzeň
2 Biomedicínské centrum LF UK Plzeň

Supporting clearance of a toxic substance by an extracorporeal removal technique is one of the advanced treatment methods applied in poisoned patient management. General indications stem from toxicokinetics of the poison while individual indications are determined by poisoning severity. The first part of this review deals in detail with particular options of extracorporeal treatment in toxicology and also with its specific application when treating lithium and salicylates poisoning or dabigatran overdose. The aim of this review is to facilitate the clinician's and nephrologist's decision making whether to indicate this invasive procedure, to communicate and summarize the existing recommendations and to highlight the most important ways of how to treat poisoning by specific toxic substances.

Keywords: extracorporeal treatment; hemodialysis; intoxication; overdose; poisoning

Received: July 4, 2018; Accepted: January 28, 2019; Published: June 1, 2019  Show citation

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Raděj J, Horák J, Harazim M, Matějovič M. Extracorporeal removal techniques in toxicology: part 1. Vnitr Lek. 2019;65(6):416-424. doi: 10.36290/vnl.2019.075.
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