Vnitr Lek 2020, 66(7):e20-e25 | DOI: 10.36290/vnl.2020.134

Risk of cardiovascular complications related to blood glucose concentration: from diabetes to prediabetes

Michael Jenšovský1, Jana Malinovská1, Ludmila Brunerová2, Veronika Vejtasová3, Rhea Saldanha1, Kristýna Kučera4, Jan Brož1
1 Interní klinika 2. LF UK a FN Motol, Praha
2 Diabetologické centrum II. interní kliniky 3. LF UK a FN Královské Vinohrady, Praha
3 Kardiologická klinika 2. LF UK a FN Motol
4 Arbeitsgemeinschaft der Belegärzte am Alice-Hospital, Darmstadt, Germany

Diabetes is an established risk factor of cardiovascular disease including the coronary heart disease (CHD) and elevates the risk of cardiovascular death 2 times. Based on current evidence the risk of acquiring the CHD increases accordingly to the level of fasting blood glucose even in the prediabetic range. In the range of 5.6-6.0 mmol/l the risk is 1.11, in the range of 6.1-6.9 mmol/l the risk is 1.17. In the range of HbA1c of 42-47 mmol/l the risk of the CHD is 1.28. The probability of the CHD occurrence therefore does indeed increase in conjunction with the fasting blood glucose levels but the dependence is not linear.

Keywords: blood glucose concentration, cardiovascular disease, diabetes mellitus, prediabetes.

Published: November 3, 2020  Show citation

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Jenšovský M, Malinovská J, Brunerová L, Vejtasová V, Saldanha R, Kučera K, Brož J. Risk of cardiovascular complications related to blood glucose concentration: from diabetes to prediabetes. Vnitr Lek. 2020;66(7):e20-25. doi: 10.36290/vnl.2020.134.
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