Vnitr Lek 2025, 71(3):E17-E25 | DOI: 10.36290/vnl.2025.038
Health aspect of airplane travel
- PaF ambulancia Internej kliniky FN Nitra
Almost 2 billion people travel aboard commercial airlines every year. Health-care providers and travellers need to be aware of the potential health risks associated with air travel. Changes resulting from three physical laws about gas occur during routine commercial flights. They lead most often to mild hypoxia and gas expansion (risk od hypoxemia, barotrauma and decompression), which can exacerbate chronic medical conditions or incite acute in-flight medical events. The association between venous thromboembolism and long-haul flights, trapping gas, jet lag, and cabin-air quality are growing health-care issues associated with air travel. In-flight medical events are increasingly frequent because a growing number of individuals (incl. elderly people and children) with pre-existing medical conditions travel by air. Resources are available onboard to assist flight crew and volunteering physicians in the management of in-flight medical emergencies. Fitness for air travel is a growing issue because many passengers are unaware of health implications associated with commercial air travel. Physicians are often expected to identify individuals unfit for air travel and give them useful advice.
Keywords: air travel, risk of hypoxemia, risk of barotrauma, risk of decompression, pulmonary hypertension, health complications.
Accepted: April 28, 2025; Published: May 16, 2025 Show citation
References
- Hodkinson PD, Smith TG. Implications of the hypobaric cabin environment during commercial air travel for passenger fitness to fly. Thorax. 2024;79(10):897-898. https://doi: 10.1136/thorax-2024-221468. PMID: 39153861.
Go to original source...
Go to PubMed...
- Franzen D, Seiler O. Der Patient als Flugpassagier. Schweiz Med Forum. 2008; 8(38):898-704.
Go to original source...
- Boyle's law. NASA. Available from https://www.grc.nasa.gov/www/BGH/boyle.html
- Wet van Dalton. Available from https://nl.wikipedia.org/wiki/Wet_van_DaltonBendz B, Rostrup M, Sevre K, Andersen TO, Sandset PM. Association between acute hypobaric hypoxia and activation of coagulation in human being. Lancet. 2000;356(9242):1657-1658. https://doi: 10.1016/S0140-6736(00)03165-2. PMID: 11089830.
Go to original source...
Go to PubMed...
- Schreijer AJ, Cannegieter SC, Meijers JC, Middeldorp S, Büller HR, Rosendaal FR. Activation of coagulation system during air travel: a crossover study. Lancet. 2006;367(9513):832-838. https://doi: 10.1016/S0140-6736(06)68339-6 PMID: 16530577.
Go to original source...
Go to PubMed...
- Malý J, Widimský J. Prevence plicní embolie a žilní trombózy. In: Widimský, J, Malý, J et al. Akutní plicní embólie a žilní trombóza. Praha: Triton. 2002;24-25, 234.
- Musil, D. Žilní onemocnění na cestách. Medical Tribune. 2019. https://www.tribune.cz/archiv/zilni-onemocneni-na-cestach/?articleNavigation=1&titleVolumeContent=1
- Coker RK, Armstrong A, Church AC, Holmes S, Naylor J, Pike K, Saunders P, Spurling KJ, Vaughn P. BTS Clinical Statement on air travel for passengers with respiratory disease. Thorax. 2022;77(4):329-350. https://doi: 10.1136/thoraxjnl-2021-218110. Epub 2022 Feb 28 PMID: 35228307; PMCID: PMC8938676.
Go to original source...
Go to PubMed...
- Muhm JM, Rock PB, McMullin DL, Jones SP, Lu IL, Eilers KD, Space DR, McMullen A. Effect of aircraft-cabin altitude on passenger discomfort. N Engl J Med. 2007;357(1),357:18-27. https://doi: 10.1056/NEJMoa062770 PMID: 17611205.
Go to original source...
Go to PubMed...
- Siedenburg J. Aktuelle Empfehlungen zur Flugreisetauglichkeit. "Herr Doktor, darf ich fliegen?". MMW Fortsch Med. 2001;143(19):22-28.
- Nicholson TT, Sznajder JI. Fitness to Fly in Patients with Lung Disease. Ann Am Thorac Soc. 2014;11(10):1614-1622. https://doi.org/10.1513/AnnalsATS.201406-234PS PMID: 25393882.
Go to original source...
Go to PubMed...
- Scarpa A, Ralli M, De Luca P, Gioacchini FM, Cavaliere M, Re M, Cassandro E, Cassandro C. Inner ear disorders in scuba divers: a review. J Int Adv Otol. 2021; 17(3):260-264. https://doi: 10.5152/iao.2021.8892. PMID: 34100753; PMCID: PMC9450052.
Go to original source...
Go to PubMed...
- West JB. High-Altitude Medicine. Am J Respir Crit Care Med. 2012;186(12):1229-1237. doi: 10.1164/rccm.201207-1323CI. Epub 2012 Oct 26.
Go to original source...
Go to PubMed...
- Henry's law. Available from https://www.researchgate.net/figure/Henrys-law-at-a-constant-temperature-the-amount-of-dissolved-gas-in-a-liquid-is_fig2_352147682Koh CH. Commercial Air Travel for Passengers With Cardiovascular Disease: Stressors of Flight and Aeromedical Impact. Curr Probl Cardiol. 2021;46(3),100746. https://doi: 10.1016/j.cpcardiol.2020.100746 Epub 2020 Nov 2. PMID: 33213942; PMCID: PMC8514285.
Go to original source...
Go to PubMed...
- The International Air Transport Association (IATA) - home. Available from https://www.iata.org/Nicholson TT, Sznajder JI. Fitness to Fly in Patients with Lung Disease. Ann Am Thorac Soc. 2014;11(10):1614-1622. https://doi.org/10.1513/AnnalsATS.201406-234PS PMID: 25393882.
Go to original source...
Go to PubMed...
- Burtscher M, Mairer K, Wille M, Gatterer H, Ruedl G, Faulhaber M, Sumann G. Short-term exposure to hypoxia for work and leisure activities in health and disease: which level of hypoxia is safe? Sleep Breath. 2012;16(2):435-442. doi: 10.1007/s11325-011-0521-1 Epub 2011 Apr 16. PMID: 21499843.
Go to original source...
Go to PubMed...
- Parsi K McGrath MA, Lord RSA. Traveller's venous thrombembolism: a review of world literature a survey of world airlines and Australian perspectives. Autr N Zealand J Phlebology. 2021;5:32-53. https://doi: 10.1016/s0967-2109(00)00116-2. PMID: 11250182.
Go to original source...
Go to PubMed...
- Rusnáková H. Trombóza cestovateľov. Via practica, Bratislava: SOLEN. 2012;9(2): 54-56. ISSN 1336-4790.
- Gavorník P. Všeobecná angiológia. Angiologická propedeutika. Cievne choroby. 2. rozšírené a doplnené vydanie. Bratislava: Univerzita Komenského - Vydavateľstvo UK.2001;268 s. ISBN10: 8022316083 ; ISBN13: 9788022316088.
- Gavorník P, Dukát A. Endotel a jeho dysfunkcia - etiopatogenéza, diagnóza, prevencia a liečba - mimoriadne aktuálny klinický problém v oblasti cievnych chorôb. Prakt Lek. 2003;83(1):6-12. https://www.internimedicina.cz/pdfs/int/2008/05/04.pdf
- Labaš P. Intervenčná liečba chronickej žilovej insuficiencie. 1. vyd. Bratislava: Vyd. Polygrafia SAV. 1999; 95 s. ISBN 80-88780-28-4.
- Lauková D. Lietadlom na dovolenku - pohľad pneumológa. 57. Nitrianske lekárske dni. 23.-24.10.2024. https://lekarskedni.sk/wp-content/uploads/2024/10/57-NLD-Oficialny-program-5_compressed.pdf.