Vnitr Lek 2026, 72(1):15-20 | DOI: 10.36290/vnl.2026.002

Current and emerging therapies in obstructive lung diseases

Kristián Brat^{1, 2, 3}

¹ Centrum pneumologie a intervenční bronchologie, Masarykův onkologický ústav, Brno

² Klinika komplexní onkologické péče, Lékařská fakulta Masarykovy univerzity, Brno

³ Katedra fyzioterapie a rehabilitace, Lékařská fakulta Masarykovy univerzity, Brno

Chronic obstructive pulmonary disease (COPD) and bronchial asthma are the two most common chronic lung diseases with an estimated global prevalence of over 300 million people each. For both diseases, updates of global strategies are published annually (the GOLD document for COPD and the GINA document for asthma) to establish a general framework for the management of these diseases. Both documents are cornerstones for the Czech national guidelines for the diagnosis and management of COPD and asthma. In recent years, a substantial scientific progress has been made in the field, that outlines the current and future directions of their management. This article presents a summary of the current guidelines in the Czech Republic. Also, modern trends from the GOLD and GINA documents are presented, along with evidence from recent studies with new pharmacological and non-pharmacological strategies.

Keywords: chronic obstructive pulmonary disease, bronchial asthma, biological treatment, exacerbation.

Accepted: February 3, 2026; Published: February 12, 2026  Show citation