Vnitr Lek 2026, 72(6):E1-E5 | DOI: 10.36290/vnl.2026.077
Changes in diabetes care assessed from the number of HbA1c assays performed during COVID pandemic in Slovakia
- 1 Faculty of Medicine, Comenius University Bratislava, Bratislava, Slovakia,
- 2 JAL Ltd., Diabetologic Outpatient Clinic, Trnava, Slovakia
- 3 Medical Faculty, Safarik University, Kosice, Slovakia
- 4 Faculty of Health Sciences, Miskolc University, Miskolc, Hungary
- 5 Cumulus Ltd., Biochemical Laboratory, Kosice, Slovakia
- 6 Institute of Health Analyses, Health Ministry of Slovak Government, Bratislava, Slovakia
- 7 Medirex Group Laboratories Inc., Pezinok, Slovakia
Introduction: In Slovakia during the first two years of COVID-19 pandemic a significant increase of mortality in diabetic patients occurred, which returned near to the initial values in its last stage (2022). Patients with diabetes mellitus need regular assessment of HbA1c. The aim of this study was evaluation of the effect of pandemic on the number of HbA1c measurements performed before (2019), during (2020; 2021), and in the last stage (2022) of pandemic.
Methods: 382 803 HbA1c measurements from Medirex Inc. laboratory chain and 23 779 assays from a local laboratory (Cumulus Inc.) were evaluated.
Results: The number of HbA1c measurements in Medirex dropped down in 2020 by 18,7%, returned slightly in 2021 and increased by 4,4% in 2022. In Cumulus the decrease in 2020 was similar to Medirex, but in the next two years no full recovery occurred. Analysis according to type of diabetes (Medirex dataset) revealed that the recovery in 2022 was present only in T2DM patients and not in those with T1DM. Analysis according to age showed a broad distribution, with a 28,3% drop in the oldest T1DM (> 75 years) and an increase by 12,6% in oldest T2DM patients. Despite the changes in assay number the overall level of compensation, assessed by HbA1c levels, remained stable.
Conclusions: The pandemic was a load test for laboratories providing biochemical assays The increased mortality of diabetic patients during the pandemic was probably not due to deteriorating of basic disease as assessed by HbA1c, but by COVID-19 and its complications.
Keywords: COVID-19, diabetes mellitus, HbA1c, glycaemic compensation
Accepted: September 16, 2026; Published: October 2, 2026 Show citation
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References
- Laires PA, Dias S, Gama A, et al. The association between chronic disease and serious COVID-19 outcomes and its influence on risk perception: Survey study and database analysis. JMIR Public Health & Surveillance [Internet]. 2021;7(???):11e22794. Available from: .
Go to original source...
Go to PubMed... - Chudasama YV, Gillies CL, Zaccardi F, et al. Impact of COVID-19 on routine care for chronic diseases: A global survey of views from healthcare professionals. Diabetes Metabol Syndr Clin Res Rev. 2020;14(???):965-967. doi: 10/1016/J.dsx.2020. 06. 042
Go to original source...
Go to PubMed... - American Diabetes Association Professional Practice Committee. Standards of Care in Diabetes - 2026. Glycemic goals, hypoglycemia, and hyperglycemic crises. Diabetes Care [Internet]. 2026;49(???):S132-S149. Available from: .
Go to original source...
Go to PubMed... - Banerjee M, Chakraborty S, Pal R. Diabetes self-management amid COVID-19 pandemic. Diabetes Metabol Syndr Clin Res Rev. 2020;14(???):351-354. doi: 10.1016//J.dsx.2020. 04. 013
Go to original source... - Chen JL, Krupp GR, Lo JY. The COVID-19 pandemic and changes in health care utilization among patients with type 2 diabetes. Diabetes Care [Internet]. 2022;45(???):e74-e76. Available from: .
Go to original source... - Palanca A, Quinones-Torrelo C, Girbés J, et al. Impact of COVID-19 lockdown on diabetes management and follow-up in a broad population in Spain. Eur J Clin Invest [Internet]. 2022;52(???):e13771. Available from: .
Go to original source...
Go to PubMed... - Amsah N, Isa ZM, Ahmad N, et al. Impact of COVID-19 pandemic on healthcare utilization among patients with type 2 diabetes mellitus: A systematic review. Int. J. Environ. Res. Public Health [Internet]. 2023;20(???):4577. Available from: .
Go to original source...
Go to PubMed... - WHO Regional Office for Europe, European Commission, European Observatory on Health Systems and Policies. COVID-19 Health Systems Response Monitor - Slovakia (2021). [Internet]. [cit.???]. Available from: .
- OECD/European Observatory on Health Systems and Policies (2021), Slovakia: Country Health Profile 2023, State of Health in the EU, OECD Publishing, Paris/European Observatory on Health Systems and Policies, Brussels. 61. ISBN 978-92-64837645. doi:10.2875/835293.
Go to original source... - Lacka J, Martinka E, Ištokovičová P, et al. Prevalence and mortality of patients with type 2 diabetes mellitus in years in years 2010-2015 and mortality during COVID-19 pandemic, April 2020 - March 2023. Diab Obez. 2023;23(???):91-100 (In Slovak).
- Cuschieri S, Grech S. COVID-19 and diabetes: The why, the what and the how J. Diabetes Comp. 2020;34(???):107637. doi.org/10.1016/j.diacomp.2020.
Go to original source...
Go to PubMed... - He Y, Zheng Q, Zhifang Z, et al. When COVID-19 meets diabetes: A bibliometric analysis. Diabetes Res Clin Pract. 2025;223(???):112118v. doi.org/10.1016/j.diabres.2025.112118
Go to original source...
Go to PubMed... - Hartmann-Boyce J, Highton P, Rees K, et al. The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review. Lancet Diab & Endocrin [Internet]. 2024;12(???):132-148. Available from: .
Go to original source... - Breznoščáková D, Pallayová M. Uncovering the untold emotional toll of living with diabetes in the COVID-19 era. Psychother Psychosom [Internet]. 2022;91(???):286-287. Available from: .
Go to original source...
Go to PubMed... - Lippi F, Henry BM, Bovo C, et al. Health risks and potential remedies during prolonged lockdowns for coronavirus disease 2019 (COVID-19). Diagnosis [Internet]. 2020;7(???):85-90. Available from: .
- Gruson D, Ko G, Luu D. COVID-19: Armageddon before light? eJIFCC. 2020;31(???):103-105. eJIFCC2020Vol31:103-105
- Holt E. COVID-19 testing in Slovakia. Lancet Infect Dis [Internet]. 2020;21(???):32. Available from: .
Go to original source...
Go to PubMed... - Luo YT, Wang HL, Zhang MM, et al. COVID-19-another influential event impacts on laboratory medicine management. J Clin Lab Anal [Internet]. 2021;35(???):e23804. Available from: .
Go to original source... - Humphries R, Sefers S, Schmitz J, et al. Clinical laboratory experiences during the COVID-19 pandemic. Clin Infect Dis [Internet]. 2024;78(???):1093-1096. Available from: .
Go to original source...
Go to PubMed... - Levin AT, Hanage WP, Owusu-Boaitey N, et al. Assessing the age specificity of infection fatality rates for COVID-19: systematic review, meta-analysis, and public policy implications. Eu J Epidem [Internet]. 2020;35(???):1123-1138. Available from: .
Go to original source...
Go to PubMed... - Abraham SA, Agyare DF, Yeboa NK, et al. The Influence of COVID-19 Pandemic on the health seeking behaviors of adults living with chronic conditions: A view through the health belief model. J Primary Care & Community Health. 2023;14(???):1-10. doi:10.1177/215013/9231/59459
Go to original source... - D'Onofrio L, Pieralice S, Maddaloni E, et al. Effects of the COVID-19 lockdown on glycaemic control in subjects with type 2 diabetes: the glycalock study. Diabetes Obes Metab. 2021;23(???):1624-1630. doi:10,1111/dom14380
Go to original source... - Eberle C, Stichling S. Impact of COVID-19 lockdown on glycemic control in patients with type 1 and type 2 diabetes mellitus: a systematic review. Diabetol Metab Syndr. 2021;13(???):1-8. doi.org/10.1186/s13098-021-00705/9
Go to original source... - Falcetta P, Aragona M, Ciccarone A, et al. Impact of COVID-19 lockdown on glucose control of elderly people with type 2 diabetes in Italy. Diab Res Clin Pract. 2021;174(???):108750. doi.org/10.1016/j.diabres.2021.108750
Go to original source...
Go to PubMed... - Ludwig L, Scheyer N, Remen T, et al. The impact of COVID-19 lockdown on metabolic control and access to healthcare in people with diabetes: the CONFI-DIAB cross-sectional study. Diabetes Ther [Internet]. 2021;12(???):2207-2221. Available from: .
Go to original source...
Go to PubMed... - Biancalana E, Parolini F, Mengozzi A, et al. Short-term impact of COVID-19 lockdown on metabolic control of patients with well-controlled type 2 diabetes: a single-centre observational study. Acta Diabetol. 2021;58(???):431-436. doi.org/10.1007/s00592-020-01367-y
Go to original source...
Go to PubMed... - Frieden TR, Lee CT, Lamorde M, et al. The road to achieving epidemic-ready primary health care. Lancet Public Health. 2023;8(???):e383-e390.
Go to original source...
Go to PubMed...




