Vnitr Lek 2013, 59(9):841-845

Regional migrating osteoporosis - a case report

I. Žofková1,*, J. Hrbáč3, J. Dostál4, J. Šprindrich2
1 Endokrinologický ústav Praha, ředitelka doc. MUDr. Běla Bendlová, CSc.
2 Radiodiagnostická klinika 3. lékařské fakulty UK a FN Královské Vinohrady Praha, přednosta doc. MUDr. Václav Janík, CSc.
3 Oddělení nukleární medicíny Slezské nemocnice v Opavě, p.o., Opava, přednosta prim. MUDr. Jiří Hrbáč
4 Oddělení radiologické Slezské nemocnice v Opavě, p.o., Opava, přednosta prim. MUDr. Milan Cvek

Regional migrating osteoporosis (RMO) was observed in young man with episodes of bone pain in bearing joints, which migrated from hip to leg and subsequently to knee on the unilateral side. Dynamic scintigraphy (SPECT) carried out during relapse of pain demonstrated increased accumulation of radioizotope in Lisfrank joint, distal epiphysis of femur and proximal epiphysis of tibia on the unilateral side due to hyperperfusion and high metabolic turnover in these regions of the skeleton. Diagnosis of RMO was confirmed by magnetic resonance (MRI), which showed bone marrow edema of corresponding regions. Although RMO is relatively benign disease with spontaneous remisions, infection etiology or the more serious avascular necrosis should be taken into account.

Keywords: regional migrating osteoporosis; bone marrow edema; avascular necrosis; dynamic scintigraphy; magnetic resonance

Received: April 3, 2013; Accepted: May 4, 2013; Published: September 1, 2013  Show citation

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Žofková I, Hrbáč J, Dostál J, Šprindrich J. Regional migrating osteoporosis - a case report. Vnitr Lek. 2013;59(9):841-845.
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