Vnitr Lek 2005, 51(10):1096-1101

Prevalence and associated factors of self medication with antibiotics in Czech Republic

R. Andrajati1,2, J. Vlček1,*, F. M. Haaijer-Ruskamp3
1 Katedra sociální a klinické farmacie Farmaceutické fakulty UK, Hradec Králové, přednosta doc. RNDr. Jiří Vlček, CSc.
2 Pharmacy Department University of Indonesia, Indonesia, přednosta Dr. Maksum Raji Ph.D.
3 Clinical Pharmacology Department University of Groningen, Netherlands, přednosta prof. Dr. D. de Zeeuw

Self medication with antibiotics (ATB) in Czech Republic (CR) is not approved by law. During the past era a very strong ATB policy and strict control of ATB use in the CR. The objectives of this study were to determine prevalence and to identified factors related of actual self medication with antibiotics and 'at risk' self medication with antibiotics.

Method:
crosss sectional design, two stage sampling, selecting a representative region, a middle size city (urban) and rural area sampling. Self administered postal questionnaire were randomly sent to to adults age ≥ 18, 1 000 respondents in urban and 1000 in rural area. Descriptive, bivariate and multivariate analysis was completed using SPSS 11.5 version.

Results:
The prevalence of ATB use with prescription was 28.0 % and actual ATB self medication was 0.5 %. The prevalence at risk of self medication with ATBs: storage ATB at home was 7.5 % and intended ATB use for themselves was 16.9 %. Amoxicillin was the most frequent of antibiotic use whereas throat symptom/complain was the most frequent reasons for use ATBs. Storage ATBs at home sources were from medical prescription, relative and from pharmacy without any prescription. The most frequent of storage ATBs at home was co-trimoxazol. The most comonly indication to use ATB without consultation with a physician was sore throath. The predictor of the ATB use with prescription were male, people which had children at home, suffered from chronic diseases, and storage ATB at home. Respondents less 35 years old, who used ATB with prescription, intended use ATB, were determinants of storage ATB at home. The people with ATB at home was predicted to be actual self medication. The predictors of intended use ATB by adults were people age less than 65 years and storage ATB home.
In

conclusion, the prevalence of actual self medication with AB was low but "at risk" self medication was higher in the ČR. The people with age less than 35 years were strong predictor for storage ATB at home and intended use ATB without consulting a physician. The people which storage ATB at home were predicted to be actual self medication.

Keywords: self medication; antibiotic; Czech Republic

Received: October 13, 2004; Accepted: February 21, 2005; Published: October 1, 2005  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Andrajati R, Vlček J, Haaijer-Ruskamp FM. Prevalence and associated factors of self medication with antibiotics in Czech Republic. Vnitr Lek. 2005;51(10):1096-1101.
Download citation

References

  1. Figueiras A, Caamano F, Gestal-Otero JJ. Sociodemographic factors related to self-medication in Spain. Eur J Epidemiol 2000; 16: 19-26. Go to original source... Go to PubMed...
  2. Gonzalez AO, Lozano MAR, Nunez JG. Analysis of automedication with antibiotics in Spain Enferm. Index Microbiol Clin 1998; 16: 328-333.
  3. Grigoryan L, Haaijer-Ruskamp FM. 18 co-investigators in Europe on behalf of Self Medication with Antibiotic. Self medication with Antibiotics in Europe. Pharmacoepidemiol Drug Safety 2004; 13: S19.
  4. Liu YC, Huang WK, Kunin CM. Inappropriate use of antibiotics and the risk for delayed admission and masked diagnosis of infectious diseases. Arch Intern Med 2001; 16: 2366-2370. Go to original source... Go to PubMed...
  5. Macfarlane J, Holmes W, Macfarlane R et al. Influence of patients' expectations on antibiotic management of acute lower respiratory tract illness in general practice: questionnaire study. BMJ 1997; 315: 1211-1214. Go to original source... Go to PubMed...
  6. Mainous III AG, Hueston WJ, Davis MP et al. Trends in antimicrobial prescribing for bronchitis and upper respiratory infections among adults and children. Am J Public Health 2003; 93: 1910-1914. Go to original source... Go to PubMed...
  7. Marliere GLL, Ferraz MB, Quirino dos Santos J. Antibiotic consumption patterns and drug leftovers in 6000 Brazilian household. Adv Ther 2000; 17: 32-44. Go to original source... Go to PubMed...
  8. McCaig LF, Besser RE, Hughes JM. Trends in antimicrobial prescribing rates for children and adolescents. JAMA 2002; 287: 3096-3102. Go to original source... Go to PubMed...
  9. Richman PB, Garra G, Eskin B et al. Oral antibiotic use without consulting a physician: A survey of ED patients. Am J Emerg Med 2001; 19: 57-60. Go to original source... Go to PubMed...
  10. Steinman MA, Landefeld CS, Gonzales R. Predictors of broad-spectrum antibiotic prescribing for acute respiratory tract infections in adult primary care. JAMA 2003; 6: 719-725. Go to original source... Go to PubMed...
  11. Steinman MA, Gonzales R, Linder JA et al. Changing use of antibiotics in community-based outpatient practice. Ann Intern Med 2003; 138: 525-533. Go to original source... Go to PubMed...
  12. Stratchounski LS, Andreeva IV, Ratchina SA et al. The inventory of antibiotics in Russian home medicine cabinets. Clin Infect Diseas 2003; 37: 498-505. Go to original source... Go to PubMed...
  13. WHO fact sheet no 194 revised January 2002: Antimicrobial resistance. http://www.who.int
  14. WHO global strategy for containment of antimicrobial resistance. 2001: http://www.who.int/emc




Vnitřní lékařství

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.