Vnitr Lek 2016, 62(12):1021-1027

Takotsubo cardiomyopathy: incidence, etiology, complications, therapy and prognosis

Milan Babický1,*, František Holm1,2, Miroslav Erbrt1
1 Kardiologie na Bulovce, s.r.o., Praha
2 Ústav zdravotnických studií Technické univerzity v Liberci

Takotsubo syndrome is presented by acute heart failure and looks like acute coronary syndrome and truly mimics its clinical and ECG features. It is characterised by transient contractility disorder of mostly apical part of left ventricle without any presence of occlusive coronary disease. It is found in 1-2 % patients admitted to the hospital care for acute coronary syndrome. Prognosis is very excellent within complete recovery of left ventricle in several weeks. The etiology is unknown and therapy just symptomatic. Transient dynamic obstruction of left ventricle output tract can be sometimes present as well as hemodynamic instability and arrhythmias. Death was rarely described. We introduce a case of takotsubo syndrome complicated by extreme high transient gradient in left ventricle output tract followed complete recovery in short time.

Keywords: complication; etiology; incidence; takotsubo syndrome; therapy

Received: April 21, 2016; Accepted: September 6, 2016; Published: December 1, 2016  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Babický M, Holm F, Erbrt M. Takotsubo cardiomyopathy: incidence, etiology, complications, therapy and prognosis. Vnitr Lek. 2016;62(12):1021-1027.
Download citation

References

  1. Sato H, Tateishi H, Uchida T. Takotsubo-type cardiomyopathy due to multivessel spasm. In: Kodama K, Haze K, Hon M, eds. Clinical Aspect of Myocardial Injury: From Ischemia to Heart Failure. Kagakuhyouronsha:Tokyo 1990: 56-64.
  2. Lyon RA, Bossone E, Schneider B et al. Current state of knowledge on takotsubo syndrome: a position statement from the task force on takotsubo syndrome of the Heart Failure Association of the European Society of Cardiology. Eur J of Heart Failure 2016; 18(1): 8-27. Dostupné z DOI: <http://dx.doi.org/10.1002/ejhf.424>. Go to original source... Go to PubMed...
  3. Kuběna P, Bohatá Š, Maňoušek J et al. Takotsubo kardiomyopatie, klinické zkušenosti s onemocněním a jednoletá prognóza pacientů. Vnitř Lék 2015; 61(7-8): 619-625. Go to PubMed...
  4. Negahban AQ, Máchal J, Panovský R et al. Neobvyklý typ takotsubo kardiomyopatie - kasuistika a aktuální přehled problematiky. Cor Vasa 2014; 56(5): e403-e410. Dostupné z DOI: <http://dx.doi.org/10.1016/j.crvasa.2013.09.004>. Go to original source...
  5. Kawai S, Kitabatake A, Tomoike H. [Takotsubo Cardiomyopathy Group]. Guidelines for diagnosis of takotsubo (ampulla) cardiomyopathy. Circ J 2007; 71(6): 990-992. Go to original source... Go to PubMed...
  6. Lindsay J, Paixao A, Chao T et al. Pathogenesis of the Takotsubo syndrome: a unifying hypothesis. Am J Cardiol 2010; 106(9): 1360-1363. Dostupné z DOI: <http://dx.doi.org/10.1016/j.amjcard.2010.06.068>. Go to original source... Go to PubMed...
  7. Afonso L, Bachour K, Awad K et al. Takotsubo cardiomyopathy: pathogenetic insights and myocardial perfusion kinetics using myocardial contrast echocardiography. Eur J Echocardiogr 2008; 9(6): 849-854. Dostupné z DOI: <http://dx.doi.org/10.1093/ejechocard/jen192>. Go to original source... Go to PubMed...
  8. Khallafi H, Chacko V, Varveralis N et al. "Broken heart syndrome": catecholamine surge or aborted myocardial infarction? J Invasive Cardiol 2008; 20(1): E9-E13. Go to PubMed...
  9. Dorfman TA, Iskandrian AE. Takotsubo cardiomyopathy: State-of-the-art review. J Nucl Cardiol 2009; 16(1): 122-134. Dostupné z DOI: <http://dx.doi.org/10.1007/s12350-008-9015-3>. Go to original source... Go to PubMed...
  10. Buchholz S, Rudan G. Tako-tsubo syndrome on the rise: a review of the current literature. Postgrad Med J 2007; 83(978): 261-264. Dostupné z DOI:<http://dx.doi.org/10.1136/pgmj.2006.052423>. Go to original source... Go to PubMed...
  11. Boland TA, Lee VH, Bleck TP. Stress-induced cardiomyopathy. Crit Care Med 2015; 43(3): 686-693. Dostupné z DOI: <http://dx.doi.org/10.1097/CCM.0000000000000851>. Go to original source... Go to PubMed...
  12. Citro R, Previtali M, Bossone E. Tako-tsubo cardiomyopathy and drowning syndrome: is there a link? Chest 2008; 134(2): 469. Dostupné z DOI: <http://dx.doi.org/10.1378/chest.08-0541>. Go to original source... Go to PubMed...
  13. Bybee KA, Prasad A, Barsness GW et al. Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome. Am J Cardiol 2004; 94(3): 343-346. Go to original source... Go to PubMed...
  14. Ito K, Sugihara H, Katoh S et al. Assessment of Takotsubo (ampulla) cardiomyopathy using 99mTc-tetrofosmin myocardial SPECT - comparison with acute coronary syndrome. Ann Nucl Med 2003; 17(2): 115-122. Go to original source... Go to PubMed...
  15. Donohue D, Movahed MR. Clinical characteristics, demographics and prognosis of transient left ventricular apical ballooning syndrome. Heart Fail Rev 2005; 10(4): 311-316. Go to original source... Go to PubMed...
  16. Buchholz S, Rudan G. Tako-tsubo syndrome on the rise: a review of the current literature. Postgrad Med J 2007; 83(978): 261-264. Go to original source... Go to PubMed...
  17. Pilgrim TM, Wyss TR. Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome: A systematic review. Int J Cardiol 2008; 124(3): 283-292. Go to original source... Go to PubMed...
  18. Prasad A, Lerman A, Rihal CS. Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 2008; 155(3): 408-417. Dostupné z DOI: <http://dx.doi.org/10.1016/j.ahj.2007.11.008>. Go to original source... Go to PubMed...
  19. Singh K, Carson K, Usmani Z et al. Systematic review and meta-analysis of incidence and correlates of recurrence of takotsubo cardiomyopathy. Int J Cardiol 2014; 174(3): 696-701. Dostupné z DOI: <http://dx.doi.org/10.1016/j.ijcard.2014.04.221>. Go to original source... Go to PubMed...
  20. Gianni M, Dentali F, Grandi AM et al. Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 2006; 27(13): 1523-1529. Go to original source... Go to PubMed...
  21. Bybee KA, Kara T, Prasad A et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann Intern Med 2004; 141(11): 858-865. Go to original source... Go to PubMed...
  22. Merchant EE, Johnson SW, Nguyen P et al. Takotsubo cardiomyopathy: a case series and review of the literature. West J Emerg Med 2008; 9(2): 104-111.
  23. Thiele G, Zeymer U, Neumann FJ et al. Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock. N Engl J Med 2012; 367(14): 1287-1296. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMoa1208410>. Go to original source... Go to PubMed...
  24. De Backer O, Debonnaire P, Gevaert S et al. Prevalence, associated factors and management implications of left ventricular outflow tract obstruction in takotstubo cardiomyopathy: a two-year, two-center experience. Cardiovascular Disorders 2014; 14: 147. Dostupné z DOI: <http://dx.doi.org/10.1186/1471-2261-14-147>. Go to original source... Go to PubMed...




Vnitřní lékařství

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.