At the intensive care unit of the hospital and policlinical department in Zilina the authors treated between May 29, 1985 and Dec. 31, 1990, 87 patients with AIM by systemic administration of streptokinase which was injected after an average period of 2.5 hours following the onset of stenocardia. As to the selection of patients for thrombolysis and tactics of treatment, the authors proceeded according to an elaborated protocol. The upper borderline of the age range is not limited. Non-invasive markers of reperfusion of the heart muscle (regression of stenocardia, regression of ECG changes, reperfusion arrhythmias) were observed in 25-80% of the patients. There was only a small number of complications in the patients of the described group; they were not serious and did not call for therapeutic intervention. Thrombolytic treatment of AIM by streptokinase is a safe and effective method which can be successfully used also in intensive care units of district hospitals.

Keywords: Adult; Aged; Female; Humans; Male; Middle Aged; Myocardial Infarction /drug therapy/; Streptokinase /therapeutic use/; Thrombolytic Therapy