Vnitr Lek 1995, 41(8):555-559

[Regulation of HDL lipoprotein plasma levels in relation to atherogenesis].

V Růzek: Interní klinika FN, Praha-Motol.

Klíčová slova: Arteriosclerosis, blood, ; Humans; Lipoproteins, HDL, blood,

There is no doubt nowadays on the importance of HDL lipoproteins in atherogenesis. In the submitted review the author presents information on the regulation of HDL lipoprotein plasma levels and their sub-classes. First he deals with metabolic relations, in particular synthesis and catabolism of HDL lipoproteins. He mentions then factors which influence plasma levels of HDL lipoproteins and their sub-classes--external and internal factors. As to internal factors the author discusses genetic predisposition, sex, age, obesity, adipose tissue distribution; as to external factors the effect of diet, exercise, alcohol, smoking and drugs.