A multicentric study was conducted in March to September 1995 to test the effectiveness and tolerance of a new insulin series. A total of 281 diabetics above 15 years of age were followed up, 144 men and 137 women, mean age 63 years with a duration of diabetes from 0.5 to 51 years, without serious organ complications and capable to recognise symptoms of hypoglycaemia. During the investigation a total of five examinations of the investigated parameters were made. The authors revealed a statistically insignificant decline of body weight, blood sugar level on fasting and HbA1c and a significant drop of the postprandial blood sugar level. The BP reading and urinary findings were unaltered. The authors found a significant drop of the daily insulin dose in MONO N, D and ID and an insignificant rise of the daily dose in MONO SD. The investigation provided evidence of a satisfactory effectiveness and tolerance of the new insulin series. In MONO N, D and ID there was also a decline in the total consumption.

Keywords: Adult; Aged; Aged, 80 and over; Blood Glucose /analysis/; Diabetes Mellitus, Type 1 /blood/; Female; Humans; Insulin /administration & dosage/; Male; Middle Aged