Vnitr Lek 2016, 62(2):100-104

Chronic pancreatitis diagnosed after the first attack of acute pancreatitis

Martina Bojková^1,*, Petr Dítě¹, Magdalena Uvírová², Nina Dvořáčková³, Bohuslav Kianička⁴, Tomáš Kupka¹, Pavel Svoboda¹, Pavel Klvaňa¹, Arnošt Martínek¹

¹ Akademické centrum gastroenterologie, Interní klinika LF OU a FN Ostrava

² CGB laboratoř a LF OU Ostrava

³ Oddělení klinické genetiky, FN Ostrava

⁴ Gastreonterologické oddělení II. interní kliniky LF MU a FN u sv. Anny Brno

Introduction:
One of the diseases involving a potential risk of developing chronic pancreatitis is acute pancreatitis.

Material:
Of the overall number of 231 individuals followed with a diagnosis of chronic pancreatitis, 56 patients were initially treated for acute pancreatitis (24.2 %). Within an interval of 12-24 months from the first attack of acute pancreatitis, their condition gradually progressed to reached the picture of chronic pancreatitis. The individuals included in the study abstained (from alcohol) following the first attack of acute pancreatitis and no relapse of acute pancreatitis was proven during the period of their monitoring.

Results:
The etiology of acute pancreatitis identified alcohol as the predominant cause (55.3 %), biliary etiology was proven in 35.7 %. According to the revised Atlanta classification, severe pancreatitis was established in 69.6 % of the patients, the others met the criterion for intermediate form, those with the light form were not included.

Conclusion:
Significant risk factors present among the patients were smoking, obesity and 18 %, resp. 25.8 % had pancreatogenous diabetes mellitus identified. 88.1 % of the patients with acute pancreatitis were smokers. The majority of individuals with chronic pancreatitis following an attack of acute pancreatitis were of a productive age from 25 to 50 years. It is not only acute alcoholic pancreatitis which evolves into chronic pancreatitis, we have also identified this transition for pancreatitis of biliary etiology.

Keywords: acute pancreatitis; chronic pancreatitis; smoking; obesity; pancreatogenous diabetes mellitus

Received: September 23, 2015; Accepted: November 21, 2015; Published: February 1, 2016  Show citation