Vnitr Lek 2022, 68(3):172-177 | DOI: 10.36290/vnl.2022.034

Hypertension and dyslipidemia treament in stroke

Barbora Nussbaumerová

Centrum preventivní kardiologie, II. interní klinika LF a FN v Plzni

Stroke is the second most common cause of mortality worldwide and the third most common cause of disability. Arterial hypertension is the most prevalent risk factor for stroke. A precise management of arterial hypertension prevents the first episode of stroke and the recurrence. Blood pressure must be decreased carefully and not very vigorously in the acute phase of the stroke. Recommended blood pressure goals in chronic tratment are at least 140 / 90 mm Hg and lower if tolerated. ACE inhibitors or angiotensin receptor blockers in combination with calcium channel blockers or indapamide are favorable antihypertensive drugs. Dyslipidemia is also a strong risk factor for ischaemic stroke and has no relatioship to the other etiologies of stroke. The cardiovascular risk in patients after a stroke is very high. An intensive hypolipidemic treatment by statins, ezetimibe and PCSK9i to LDL-cholesterol goals < 1,4 mmol/l and a 50% decrease was proved to decrease the incidence of recurrent stroke.

Keywords: arterial hypertension, dyslipidemia, stroke, antihypertensive drugs, hypolipidemic drugs, statin, ezetimibe, PCSK9i, secondary prevention.

Published: April 26, 2022  Show citation