Vnitřní lékařství, 1998 (vol. 44), issue 8
[Effect of H. pylori eradication regimes on the proliferation index of gastric mucosa].
A Hep, J Zaloudík, J Janáková, B Habanec, J Prásek, J Dolina, P Dítě
Vnitr Lek 1998, 44(8):447-450
Eradication regimes with the blocking agent of the proton pump and without it do not influence the activity of cell division after treatment of Helicobacter pylori (H.p.) when using cytoflowmetric evaluation. The non-significant difference in proliferation activity of the gastric mucosa after treatment of H.p. can be also a sign of more rapid repair of the gastric mucosa after elimination of the inflammatory elements.
[Erythropoietin in non-specific intestinal inflammation].
M Hertlová, V Zboril, J Kautská, A Pokorný, L Prokopová
Vnitr Lek 1998, 44(8):451-455
In 39 patients with non-specific intestinal inflammations the authors examined the erythropoietin level. They found a significantly higher level of serum erythropoietin in patients during relapse, when the organism responds to more severe anaemia by increased erythropoietin production. The idea that the reactivity of the bone marrow or effectiveness of erythropoietin is influenced by mediators of the inflammation is supported by the fact that the group comprised patients with high erythropoietin values of 102, 106.6, 109 and 445 ImU/l but their anaemia did not improve markedly. The theory on an inadequate erythropoietin secretion is supported by the...
[The fatigue syndrome in autoimmune thyroiditis with polyglandular activation of autoimmunity].
I Sterzl, T Fucíková, P Hrdá, P Matucha, V Zamrazil
Vnitr Lek 1998, 44(8):456-460
The authors compared in a group of 118 patients with autoimmune thyroiditis and a positive antibody titre against ovaries the grade of fatigue with the presence of organ specific and non-specific autoantibodies in the peripheral blood stream, antibodies against EBV and CMV, immunoglobulin concentrations, biochemical parameters of the lipid metabolism, glucose tolerance, ion balance and melatonin and serotonin levels. Patients with autoimmune thyroiditis were differentiated according to the degree of fatigue into three groups: 38 with fatigue typical for CFS, 30 with occasional fatigue and 50 without the feeling of fatigue. Fatigue of the CSF type was...
[Treatment of Graves' ophthalmopathy with irradiation].
P Slampa, V Spurný, Z Seneklová, D Krákorová
Vnitr Lek 1998, 44(8):461-463
Orbital radiation therapy appears to be an effective and safe treatment of Graves' ophthalmopathy. Five patients with Graves' ophtalmopathy were treated with external beam radiotherapy during 1996 and 1997 in St. Ann University Hospital. Four of them patients had a past history of hyperthyreoidism, one hypothyreoidism. The radiotherapy was performed with high-energy beam of a linear accelerator. The technique of irradiation employs 2 opposed beams tilted 5 degrees posteriorly. The use of the asymetric jaws is necessary to protect surrounding normal tissues. A course of radiotherapy 20.0 Gy (2.0 Gy per fraction) was given to the patients. The therapy...
[Effect of Kliogest on bone metabolism, bone mineral density and quality of life in postmenopausal patients].
J Wendlová
Vnitr Lek 1998, 44(8):464-468
UNLABELLED: The author investigated postmenopausal patients (with a natural menopause) (n = 32) where ammenorrhoea persisted for 1-2.2 years. They found a reduced bone mineral density (BMD) (ostoeopenia or osteoporosis) and laboratory tests revealed signs of increased bone turnover (so-called "fast losers"). Before administration of Kliogest R tablets, Novo Nordisk, Denmark, (1 tablet per day) and after 12 months the following parameters were evaluated: 1. Laboratory parameters of bone turnover: serum osteocalcin (OC) amino-terminal N-telopeptide of collagen I in 24-hour diuresis (NTx). 2. Bone mineral desnity (BMD) in lumbal vertebrae L1-L4 assessed...
[Gaucher's disease in a 22-year-old female patient].
A Gaja, N Hejlová, Z Churý, H Franková
Vnitr Lek 1998, 44(8):469-471
Gaucher's disease is a sphingolipidosis with a genetically conditioned deficiency of cerebroside-beta-glucosidase which can be encountered in everyday practice and not only in paediatrics. The authors submit the case-history of a 22-year-old Ukrainian patient with a fully developed type 1 Gaucher disease, and a brief review of the diagnostic and therapeutic possibilities. Due to the more extensive migration of the population on the territory of the Czech Republic a more frequent occurrence of the disease can be envisaged.
[Sarcoidosis of the liver, a granulomatous process with an unclear prognosis].
Z Frysák, V Kolek, Y Hrcková, V Jezdinská
Vnitr Lek 1998, 44(8):472-474
The authors demonstrate on two patients the pitfalls of the diagnosis and prognostic uncertainty of systemic sarcoidosis. The typical pulmonary finding was in the background due to the very extensive and serious affection of the liver.
[Malnutrition in a patient with short-bowel syndrome].
J Vecer, H Kubátová, J Hoch, Z Jech, M Kvapil, J Charvát
Vnitr Lek 1998, 44(8):475-477
The short bowel syndrome is a relatively frequent complication of extensive resection and by reducing the absorption capacity the function of the gut is markedly impaired. An important part of postoperative care is therefore to ensure nutrition of these patients. The authors demonstrate on the case-history of a 40-year-old patient after repeated revision of the abdominal cavity on account of adhesions the development of severe malnutrition after jejunotransversoanastomosis. As the small intestine was not resected (concurrent blind loop syndrome), the patient was indicated for surgery. After surgery all complaints disappeared and the nutritional status...
[CA 125 in the department of internal medicine--a marker of ovarian tumor, thoracic fluid or ascites?].
P Kasalický, J Kocián
Vnitr Lek 1998, 44(8):478-480
The authors describe three cases of falsely elevated values of the tumour marker CA 125 which in medical practice is considered above all a sign of ovarian tumours. In one case CA 125 was elevated in fibrinopurulent pleuropneumonia and refractory ascites and in one instance haemorrhagic fluidothorax was involved associated with pleuritis and in one instance an abscess of the subhepatic region. From data in the literature ensues that this increase can be associated with activation of mesothelioma cells (either in the pleura or peritoneum) in non-malignant diseases. Therefore in patients with elevated CA 125 and fluidothorax or ascites, unless ovarian...
[Thrombophilic states].
L Chrobák, P Dulícek
Vnitr Lek 1998, 44(8):481-486
Thrombophilia is defined as an increased tendency to thrombosis and can be inherited or acquired. The thrombotic events in patients with inherited thrombophilia tend to occur at a young age, are often idiopathic, recurrent and may occur at unusual sites (e.g. mesenteric, portal and cerebral veins and in inferior vena cava). The most common of the hereditary defects appear to be antithrombin, protein C, protein S deficiency, which account for 10% of individuals presenting with venous thromboembolism, resistance to anticoagulant effect of activated protein C (APC-R), which is present in 17 to 64% of patients with thrombosis and prothrombin 20210 G-->A...
[Ultrasonic tissue characterisation in cardiology].
J Meluzín, J Toman
Vnitr Lek 1998, 44(8):487-490
Ultrasonic tissue characterization is a relatively new non-invasive examination method the application of which in cardiology is steadily increasing. It is therefore the objective of the present work to summarize hitherto assembled knowledge on the use of this method in clinical practice. Ultrasonic tissue characterization uses scattering of ultrasonic waves which penetrate into the heart muscle. This scatter is due to particles inside the heart muscle, their size being smaller than the wave length of the incident ultrasonic undulation. Evaluation of the intensity of the backscatter makes it possible to evaluate structural and functional changes of...
[Electrophysiologic mechanisms of atrial rhythm disorders. I. Atrial fibrillation].
B Stancák
Vnitr Lek 1998, 44(8):491-495
Atrial fibrillation (AF) is a frequent finding in clinical practice. In advanced age its incidence is rising and according to the literature the prevalence is as high as 3.2-11%. AF doubles the mortality and brings a fivefold risk of the most frequent embolic complication--a cerebrovascular attack. The typical electrophysiological feature are intra-atrial defects of the conduction and the absence of refractory period adaptation with regard to the cycle length. In 1962 Moe, based on experimental work, postulated the hypothesis on multiple independent wavelets which move in a random fashion through the myocardium round several islets or strips of refractory...
[Differential diagnosis of mushroom poisoning].
P Gavorník
Vnitr Lek 1998, 44(8):496-501
Mushroom poisoning is a very urgent problem of internal medicine. Mushroom picking is one of the most popular hobbies in the Czech and Slovak Republic. This is one of the main reasons of the rising incidence of mushroom poisoning, incl. fatal cases. Mushroom poisoning is characterized by a very varied clinical picture which is reflected also in recent classification systems. The main objective of the present work is to draw attention to cardinal symptoms and signs of different types of mushroom poisoning which respect new findings in the diagnosis and differential diagnosis of mushroom poisoning.
[Minocycline in the treatment of rheumatoid arthritis].
S Alusík
Vnitr Lek 1998, 44(8):502-504
The author presents a review of contemporary knowledge on the treatment of rheumatoid arthritis with minocycline. He analyzes the assumed mechanism of action, dosage and the most frequently encountered undesirable effects of treatment. He informs the reader on the results of the most important studies with minocycline.