Mým kolegům!

Richard Češka

Vnitr Lek 2006, 52(11):1001  

Pozitronová emisní tomografie v diagnostice vaskulitid velkých cév - jedné z příčin horeček neznámého původu - editorial

P. Koranda, M. Mysliveček

Vnitr Lek 2006, 52(11):1002-1003  

C-reaktivní protein - editorial

Š. Svačina

Vnitr Lek 2006, 52(11):1004-1005  

Mitrální regurgitace 2006 - editorial

R. Čerbák

Vnitr Lek 2006, 52(11):1006-1009  

Mužská hormonální antikoncepce - editorial

V. Kubíček

Vnitr Lek 2006, 52(11):1010-1011  

Klinické důsledky TRIM (Transfusion related immunomodulation) - editorial

M. Průcha

Vnitr Lek 2006, 52(11):1012-1013  

Risky medication and contrast media-induced nephropathy in patients with diabetes and hypertension

D. Krusová, K. Ševela, D. Králová, P. Žák, V. Olšovská

Vnitr Lek 2006, 52(11):1014-1020  

Contrast media-induced nephropathy (CMIN) is accompanied by high morbidity, lengthy hospitalization, and a higher mortality rate. In proportion to the rising number of diagnostic and interventional radiological procedures, the prevalence of this complication is also rising The study briefly tackles the currently known pathophysiological mechanisms that lead to CMIN and deals with various risk factors which increase the probability of development of contrast nephropathy. Among these factors are, in the first place, diabetes mellitus, a pre-existing renal illness and hypertension. In addition, the risk of developing CMIN significantly increases in patients...

Late complications of chronic respiratory infections in patients with common variable immunodeficiency

O. Kopecký, Š. Lukešová, V. Koblížek, V. Vroblová, J. Novotný

Vnitr Lek 2006, 52(11):1021-1029  

Common variable immunodeficiency (CVID) is the most frequent serious humoral deficiency manifested in adulthood in the form of acute and chronic respiratory infections which in most patients lead to respiratory failure. Retrospective analysis of 28 CVID patients was made. Mean age at time of diagnosis was 38.6 ± 18.6 years. The time which elapsed from the first symptoms to determining the diagnosis was three times as long as that indicated in other studies, i.e. 14.1 ± 10.2 years. Twenty-three patients (82.1 %) had respiratory complications. Chronic obstructive pulmonary diseases, n = 16 (57.1 %), and bronchiectasis, n = 10 (35.7 %),...

The importance of anamnesis in differential diagnosis of reflex and cardiogenic syncope

P. Mitro, P. Kirsch, Z. Zausinová

Vnitr Lek 2006, 52(11):1030-1036  

The aim of the study was to establish the difference in the anamnestic data in cardiogenic and reflex syncope during a systematic gathering of data using a structured questionnaire and to measure the benefits of structured clinical history in differential diagnosis of syncope. Methodology:70 patients with syncope of undetermined etiology (average age 51 years, 26 men and 44 women) underwent a standard diagnostic protocol procedure. Cardiogenic syncope was diagnosed in 16 patients (23 %), vasovagal syncope in 34 patients (49 %), in 20 patients (28 %) the cause of the syncope remained uncertain. Anamnestic data was collected through a...

¹⁸F-FDG PET in the diagnosis of large vessel vasculitis

Z. Řehák, Z. Fojtík, J. Staníček, K. Bolčák, L. Fryšáková

Vnitr Lek 2006, 52(11):1037-1044  

Introduction:Positron emission tomography (PET) is a non-invasive diagnostic method which shows the bio-distribution of positron emitter labelled radiopharmaceuticals in the body. Due to the fact that not only timorous, but in certain conditions also some inflammatory cells may exhibit increased accumulation of 18F-FDG, 18F-FDG PET can be used in the diagnosis of both tumours and certain types of inflammations. Objective:The objective of the study is to asses the benefits of 18F-FDG PET in the patients examined for symptoms of fever of uncertain origin whose results suggested the possibility of large vessel vasculitis. Sample...

Prevalence of C-reactive protein levels in adult population in two regions in the Czech Republic and their relation to body composition

J. Čeřovská, P. Hoskovcová, M. Vosátková, H. Zamrazilová, V. Zamrazil

Vnitr Lek 2006, 52(11):1045-1050  

Increased concentration of high sensitivity C-reactive protein (hsCRP) is the new predictor of myocardial infarction, brain strokes, damage peripheral veins and sudden death. The aim of the study was to give an overview of current prevalence of individual risky concentrations of hsCRP in the adult population in two regions in the Czech Republic and to find a relationship to the indicators of fat tissue quantity. Methods:test involved a representative sample of 516 adults aged 18 to 65 years (191 men and 322 women), with permanent residence in the Jablonec nad Nisou a Příbram regions. Period of testing: spring of 2004 and 2005. HsCRP...

Dyslipidemia in patients being treated with peritoneal dialysis

A. Zharfbin

Vnitr Lek 2006, 52(11):1051-1057  

Dyslipidemia endangers nephrological patients by its aterogenic effect as well as by the possibility of acceleration of renal damage progression. The aim of our work was:1. To determine the influence of peritoneal dialysis (PD) with standard (glucose) dialysis solution on concentration of blood lipids and lipoproteins during 30 months of treatment. 2. To compare these results with a group of patients on hemodialysis (HD) and in pre-dialysis (in patients with plasmatic creatinine 250-400 μmol/l). Methods:Concentrations of total cholesterol, LDL-cholesterol, HDL-cholesterol, non-HDL-cholesterol, triglycerides, lipoproteins(a),...

Mitral regurgitation: are we able to properly time the surgical procedure?

H. Línková, M. Pěnička, P. Gregor

Vnitr Lek 2006, 52(11):1058-1065  

This overview study assesses the current view on mitral regurgitation from a theoretical, but more so, a clinical perspective. The aim of the study is to divide the different types of mitral regurgitation from the point of view of the causes and to shed light on the contrasting approaches to surgical procedure indications in individual types of mitral regurgitation.

Tako-tsubo syndrome - new addition in the family of acute states in cardiology. Current report

J. Vopelková, J. Veselka

Vnitr Lek 2006, 52(11):1066-1068  

Tako-tsubo syndrome is most often described as temporary disorder in the kinetics in the apical part of the left ventricle. Typical of this state is pronounced dyskinesis, coupled in certain cases with intraventricular obstruction. The symptom can be accompanied by a dramatic clinical picture resembling myocardial infarction. However, the findings on the coronary veins tend to be normal and the patient's prognosis is favourable. To do a proper diagnosis, it is of primary importance to bear in mind the possibility of tako-tsubo syndrome.

Affection of cardiovascular system in diabetic patients with thyroid dysfunctions

Z. Schroner, I. Lazúrová

Vnitr Lek 2006, 52(11):1069-1076  

Affection of cardiovascular system is one of the most frequent and - especially in higher age groups - the most serious clinical manifestations of thyroid dysfunction. Moreover, diabetics, mainly type 2 diabetes patients, have a marked predisposition to cardiovascular diseases, especially to atherosclerosis and its visceral complications. Simultaneous occurrence of diabetes mellitus (DM) and thyroid dysfunctions involves a very high risk of development and progression of various forms of cardiovascular diseases. There are two basal aspects of the influence of hypothyreosis on cardiovascular system. Decreasing basal metabolism in the whole organism...

Male hormonal contraception

I. Poršová-Dutoit

Vnitr Lek 2006, 52(11):1077-1084  

Human reproduction is a complex phenomenon remaining at the center of interest of many medical and extra-medical disciplines and the search for new contraceptive methods is an important part of research effort. The development of effective forms of male hormonal contraception (MHC) is one of the priorities of the World Health Organization (WHO Task Force on Methods of Regulation of Male Fertility). The principle of MHC consists in the suppression of spermatogenesis while preserving all other functional aspects of the male glands (especially the sexual functions, bone metabolism and lean muscle mass). It is possible to stop spermatogenesis by blocking...

Transfusion-induced immunomodulation and infectious complications

M. Bucová, M. Mistrík

Vnitr Lek 2006, 52(11):1085-1092  

Transfusions are not without risk. One of the side effects of transfusions is the development of transfusion-induced immunomodulation (TRIM) - primarily immunosuppression, but also a strong proinflammatory effect. This may be the cause of acute lung injury (TRALI), multiorgan failure (MOF), transfusion related acute-graft-versus-host-disease (TR AGvHD), as well as of the development of secondary nosocomial infections, mostly pulmonary infections, sepsis and wound infections, and also of elevated number of tumour relapses in oncological patients. The causes of TRIM development are the induction of microchimerism, different cells and also soluble factors...

Massive pulmonary embolism - attempt at embolectomy following the failure of thrombolytic treatment

M. Třetina, E. Petrikovits, B. Slaná, P. Rotterová, J. Černý, M. Kala, M. Orban

Vnitr Lek 2006, 52(11):1093-1096  

We report a case of a 61-year old woman with progressive dyspnoea, fatigue and tiredness over the last two weeks. Based on physical examination on admission, ECHO and CT exams, a diagnosis of massive pulmonary embolism was confirmed and the patient received thrombolytic treatment. Since no response to thrombolysis was apparent and the patient was clinically unstable with persisting signs of right ventricular dysfunction in echocardiography, a rescue surgical embolectomy was ordered and performed using cardiopulmonary bypass. Multiple large clots were removed from both pulmonary arteries. Following embolectomy, severe irreversible right ventricular...

XIII. sjezd České internistické společnosti, Brno, 1.-4. listopadu 2006. Sborník abstrakt k přednáškám

Vnitr Lek 2006, 52(11):1099-1134